Youssef Mouhayar1, Jason M Franasiak2, Fady I Sharara3,4. 1. Department of OB/GYN, University of Miami/Jackson Memorial Hospital, Miami, FL, USA. ymouhayar@med.miami.edu. 2. IVI RMA New Jersey, Basking Ridge, NJ, USA. 3. Virginia Center for Reproductive Medicine, Reston, VA, USA. 4. Department of OB/GYN, George Washington University, Washington, DC, USA.
Abstract
PURPOSE: The aim of the systematic review is to describe the obstetrical complications associated with pregnancies in the context of a thin endometrial lining. METHODS: Systematic review of the literature. RESULTS: Patients who conceive in the setting of a thin endometrium have a significantly increased risk of early pregnancy loss, namely miscarriage and ectopic pregnancy. These patients also have a twofold increase in low birth weight and preterm delivery, as well as a significantly higher risk of intrauterine growth restriction and composite adverse perinatal outcomes. CONCLUSIONS: In addition to the lower probability of conception, a thin endometrium in assisted reproductive technologies appears to be associated with both early and late pregnancy complications. These pregnancies thus warrant special attention and close follow-up from obstetricians.
PURPOSE: The aim of the systematic review is to describe the obstetrical complications associated with pregnancies in the context of a thin endometrial lining. METHODS: Systematic review of the literature. RESULTS:Patients who conceive in the setting of a thin endometrium have a significantly increased risk of early pregnancy loss, namely miscarriage and ectopic pregnancy. These patients also have a twofold increase in low birth weight and preterm delivery, as well as a significantly higher risk of intrauterine growth restriction and composite adverse perinatal outcomes. CONCLUSIONS: In addition to the lower probability of conception, a thin endometrium in assisted reproductive technologies appears to be associated with both early and late pregnancy complications. These pregnancies thus warrant special attention and close follow-up from obstetricians.
Authors: Karine Chung; Christos Coutifaris; Raffi Chalian; Kathleen Lin; Sarah J Ratcliffe; Arthur J Castelbaum; Martin F Freedman; Kurt T Barnhart Journal: Fertil Steril Date: 2006-10-30 Impact factor: 7.329
Authors: Annemieke Kasius; Janine G Smit; Helen L Torrance; Marinus J C Eijkemans; Ben Willem Mol; Brent C Opmeer; Frank J M Broekmans Journal: Hum Reprod Update Date: 2014-03-23 Impact factor: 15.610