Literature DB >> 3067981

Immunohistochemical localization of glutathione peroxidase in ocular tissue.

L R Atalla1, A Sevanian, N A Rao.   

Abstract

In this study enzyme glutathione peroxidase was localized in ocular tissue of Lewis rats using the peroxidase antiperoxidase immunohistochemical technique. Antisera to glutathione peroxidase was raised in a rabbit. Immunoreactive glutathione peroxidase was found to be distributed predominantly in the corneal epithelium and endothelium, choroid, inner segment of photoreceptors and retinal pigmented epithelium. Its presence in these sites suggests an adaptation to oxidative stress where this antioxidant enzyme along with other antioxidant systems serves to prevent damage.

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Year:  1988        PMID： 3067981     DOI： 10.3109/02713688809015149

Source DB:  PubMed          Journal:  Curr Eye Res        ISSN： 0271-3683            Impact factor:   2.424


  10 in total

1.  "Oxidative protector" enzymes in the macular retinal pigment epithelium of aging eyes and eyes with age-related macular degeneration.

Authors:  R N Frank
Journal:  Trans Am Ophthalmol Soc       Date:  1998

Review 2.  Focus on molecular events in the anterior chamber leading to glaucoma.

Authors:  Sergio Claudio Saccà; Alberto Izzotti
Journal:  Cell Mol Life Sci       Date:  2013-10-19       Impact factor: 9.261

Review 3.  Retinal light damage: mechanisms and protection.

Authors:  Daniel T Organisciak; Dana K Vaughan
Journal:  Prog Retin Eye Res       Date:  2009-12-03       Impact factor: 21.198

Review 4.  Ultraviolet radiation: cellular antioxidant response and the role of ocular aldehyde dehydrogenase enzymes.

Authors:  Satori A Marchitti; Ying Chen; David C Thompson; Vasilis Vasiliou
Journal:  Eye Contact Lens       Date:  2011-07       Impact factor: 2.018

5.  Antioxidant enzymes in the human iris: an immunogold study.

Authors:  G E Marshall
Journal:  Br J Ophthalmol       Date:  1997-04       Impact factor: 4.638

6.  Influence of oxygen free radicals and free radical scavengers on the growth behaviour and oxidative tissue damage of bovine retinal pigment epithelium cells in vitro.

Authors:  A J Augustin; S Hunt; W Breipohl; T Böker; M Spitznas
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1996-01       Impact factor: 3.117

Review 7.  Antioxidant defenses in the ocular surface.

Authors:  Ying Chen; Gaurav Mehta; Vasilis Vasiliou
Journal:  Ocul Surf       Date:  2009-10       Impact factor: 5.033

Review 8.  Role of oxygen free radicals in retinal damage associated with experimental uveitis.

Authors:  N A Rao
Journal:  Trans Am Ophthalmol Soc       Date:  1990

Review 9.  Oxidative stress to the cornea, changes in corneal optical properties, and advances in treatment of corneal oxidative injuries.

Authors:  Cestmir Cejka; Jitka Cejkova
Journal:  Oxid Med Cell Longev       Date:  2015-03-11       Impact factor: 6.543

10.  Role of Schwann Cells in Preservation of Retinal Tissue Through Reduction of Oxidative Stress.

Authors:  Alireza Lashay; Raziyeh Mahmoudzadeh; Saeed Heidari Keshel; Asieh Naderi; Roghiyeh Omidi; Fahimeh Asadi Amoli
Journal:  Med Hypothesis Discov Innov Ophthalmol       Date:  2019-10-01
  10 in total

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