Literature DB >> 30675010

Mutant p53 enhances leukemia-initiating cell self-renewal to promote leukemia development.

Sarah C Nabinger1, Sisi Chen2, Rui Gao1, Chonghua Yao1,3, Michihiro Kobayashi1, Sasidhar Vemula1, Aidan C Fahey1, Christine Wang1, Cecil Daniels1, H Scott Boswell4, George E Sandusky5, Lindsey D Mayo1, Reuben Kapur1, Yan Liu6,7.   

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Year:  2019        PMID: 30675010      PMCID: PMC9202234          DOI: 10.1038/s41375-019-0377-0

Source DB:  PubMed          Journal:  Leukemia        ISSN: 0887-6924            Impact factor:   12.883


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  15 in total

Review 1.  Targeting leukemic stem cells by breaking their dormancy.

Authors:  Marieke Alida Gertruda Essers; Andreas Trumpp
Journal:  Mol Oncol       Date:  2010-06-09       Impact factor: 6.603

Review 2.  Molecular therapy for acute myeloid leukaemia.

Authors:  Catherine C Coombs; Martin S Tallman; Ross L Levine
Journal:  Nat Rev Clin Oncol       Date:  2015-12-01       Impact factor: 66.675

3.  Profiling of somatic mutations in acute myeloid leukemia with FLT3-ITD at diagnosis and relapse.

Authors:  Manoj Garg; Yasunobu Nagata; Deepika Kanojia; Anand Mayakonda; Kenichi Yoshida; Sreya Haridas Keloth; Zhi Jiang Zang; Yusuke Okuno; Yuichi Shiraishi; Kenichi Chiba; Hiroko Tanaka; Satoru Miyano; Ling-Wen Ding; Tamara Alpermann; Qiao-Yang Sun; De-Chen Lin; Wenwen Chien; Vikas Madan; Li-Zhen Liu; Kar-Tong Tan; Abhishek Sampath; Subhashree Venkatesan; Koiti Inokuchi; Satoshi Wakita; Hiroki Yamaguchi; Wee Joo Chng; Shirley-Kow Yin Kham; Allen Eng-Juh Yeoh; Masashi Sanada; Joanna Schiller; Karl-Anton Kreuzer; Steven M Kornblau; Hagop M Kantarjian; Torsten Haferlach; Michael Lill; Ming-Chung Kuo; Lee-Yung Shih; Igor-Wolfgang Blau; Olga Blau; Henry Yang; Seishi Ogawa; H Phillip Koeffler
Journal:  Blood       Date:  2015-10-05       Impact factor: 22.113

4.  TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome.

Authors:  Frank G Rücker; Richard F Schlenk; Lars Bullinger; Sabine Kayser; Veronica Teleanu; Helena Kett; Marianne Habdank; Carla-Maria Kugler; Karlheinz Holzmann; Verena I Gaidzik; Peter Paschka; Gerhard Held; Marie von Lilienfeld-Toal; Michael Lübbert; Stefan Fröhling; Thorsten Zenz; Jürgen Krauter; Brigitte Schlegelberger; Arnold Ganser; Peter Lichter; Konstanze Döhner; Hartmut Döhner
Journal:  Blood       Date:  2011-12-20       Impact factor: 22.113

Review 5.  Targeting the FMS-like tyrosine kinase 3 in acute myeloid leukemia.

Authors:  R Swords; C Freeman; F Giles
Journal:  Leukemia       Date:  2012-04-27       Impact factor: 11.528

Review 6.  Dysfunctional diversity of p53 proteins in adult acute myeloid leukemia: projections on diagnostic workup and therapy.

Authors:  Miron Prokocimer; Alina Molchadsky; Varda Rotter
Journal:  Blood       Date:  2017-06-12       Impact factor: 22.113

Review 7.  Drugging the p53 pathway: understanding the route to clinical efficacy.

Authors:  Kian Hoe Khoo; Khoo Kian Hoe; Chandra S Verma; David P Lane
Journal:  Nat Rev Drug Discov       Date:  2014-03       Impact factor: 84.694

Review 8.  When mutants gain new powers: news from the mutant p53 field.

Authors:  Ran Brosh; Varda Rotter
Journal:  Nat Rev Cancer       Date:  2009-08-20       Impact factor: 60.716

9.  p53 regulates hematopoietic stem cell quiescence.

Authors:  Yan Liu; Shannon E Elf; Yasuhiko Miyata; Goro Sashida; Yuhui Liu; Gang Huang; Silvana Di Giandomenico; Jennifer M Lee; Anthony Deblasio; Silvia Menendez; Jack Antipin; Boris Reva; Andrew Koff; Stephen D Nimer
Journal:  Cell Stem Cell       Date:  2009-01-09       Impact factor: 24.633

10.  Genotoxic stresses promote clonal expansion of hematopoietic stem cells expressing mutant p53.

Authors:  S Chen; R Gao; C Yao; M Kobayashi; S Z Liu; M C Yoder; H Broxmeyer; R Kapur; H S Boswell; L D Mayo; Y Liu
Journal:  Leukemia       Date:  2017-11-16       Impact factor: 11.528

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  6 in total

1.  Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML.

Authors:  C D DiNardo; I S Tiong; A Quaglieri; S MacRaild; S Loghavi; F C Brown; R Thijssen; G Pomilio; A Ivey; J M Salmon; C Glytsou; S A Fleming; Q Zhang; H Ma; K P Patel; S M Kornblau; Z Xu; C C Chua; Xufeng Chen; P Blombery; C Flensburg; N Cummings; I Aifantis; H Kantarjian; D C S Huang; A W Roberts; I J Majewski; M Konopleva; A H Wei
Journal:  Blood       Date:  2020-03-12       Impact factor: 22.113

Review 2.  AML chemoresistance: The role of mutant TP53 subclonal expansion and therapy strategy.

Authors:  Bowen Yan; David Claxton; Suming Huang; Yi Qiu
Journal:  Exp Hematol       Date:  2020-06-20       Impact factor: 3.084

Review 3.  Drug Resistance Mechanisms of Acute Myeloid Leukemia Stem Cells.

Authors:  Jialan Niu; Danyue Peng; Lingbo Liu
Journal:  Front Oncol       Date:  2022-07-05       Impact factor: 5.738

4.  A unique role of p53 haploinsufficiency or loss in the development of acute myeloid leukemia with FLT3-ITD mutation.

Authors:  Min Yang; Zengkai Pan; Kezhi Huang; Guntram Büsche; Hongyun Liu; Gudrun Göhring; Regina Rumpel; Oliver Dittrich-Breiholz; Steven Talbot; Michaela Scherr; Anuhar Chaturvedi; Matthias Eder; Julia Skokowa; Jianfeng Zhou; Karl Welte; Nils von Neuhoff; Ligen Liu; Arnold Ganser; Zhixiong Li
Journal:  Leukemia       Date:  2021-11-03       Impact factor: 11.528

5.  Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway.

Authors:  Sisi Chen; Qiang Wang; Hao Yu; Maegan L Capitano; Sasidhar Vemula; Sarah C Nabinger; Rui Gao; Chonghua Yao; Michihiro Kobayashi; Zhuangzhuang Geng; Aidan Fahey; Danielle Henley; Stephen Z Liu; Sergio Barajas; Wenjie Cai; Eric R Wolf; Baskar Ramdas; Zhigang Cai; Hongyu Gao; Na Luo; Yang Sun; Terrence N Wong; Daniel C Link; Yunlong Liu; H Scott Boswell; Lindsey D Mayo; Gang Huang; Reuben Kapur; Mervin C Yoder; Hal E Broxmeyer; Zhonghua Gao; Yan Liu
Journal:  Nat Commun       Date:  2019-12-11       Impact factor: 17.694

Review 6.  Fate of Hematopoiesis During Aging. What Do We Really Know, and What are its Implications?

Authors:  Hal E Broxmeyer; Yan Liu; Reuben Kapur; Christie M Orschell; Arafat Aljoufi; James P Ropa; Thao Trinh; Sarah Burns; Maegan L Capitano
Journal:  Stem Cell Rev Rep       Date:  2020-11-03       Impact factor: 5.739

  6 in total

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