Literature DB >> 29263439

Genotoxic stresses promote clonal expansion of hematopoietic stem cells expressing mutant p53.

S Chen1, R Gao2, C Yao2,3, M Kobayashi2, S Z Liu2, M C Yoder2, H Broxmeyer4, R Kapur2, H S Boswell5, L D Mayo1,2, Y Liu1,2.   

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Year:  2017        PMID： 29263439      PMCID： PMC5842141          DOI： 10.1038/leu.2017.325

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  18 in total

Review 1.  Molecular pathophysiology of myelodysplastic syndromes.

Authors:  R Coleman Lindsley; Benjamin L Ebert
Journal:  Annu Rev Pathol       Date:  2012-08-28       Impact factor: 23.472

2.  p53-mediated hematopoietic stem and progenitor cell competition.

Authors:  Tanya Bondar; Ruslan Medzhitov
Journal:  Cell Stem Cell       Date:  2010-04-02       Impact factor: 24.633

3.  TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome.

Authors:  Frank G Rücker; Richard F Schlenk; Lars Bullinger; Sabine Kayser; Veronica Teleanu; Helena Kett; Marianne Habdank; Carla-Maria Kugler; Karlheinz Holzmann; Verena I Gaidzik; Peter Paschka; Gerhard Held; Marie von Lilienfeld-Toal; Michael Lübbert; Stefan Fröhling; Thorsten Zenz; Jürgen Krauter; Brigitte Schlegelberger; Arnold Ganser; Peter Lichter; Konstanze Döhner; Hartmut Döhner
Journal:  Blood       Date:  2011-12-20       Impact factor: 22.113

4.  Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence.

Authors:  Giulio Genovese; Anna K Kähler; Robert E Handsaker; Johan Lindberg; Samuel A Rose; Samuel F Bakhoum; Kimberly Chambert; Eran Mick; Benjamin M Neale; Menachem Fromer; Shaun M Purcell; Oscar Svantesson; Mikael Landén; Martin Höglund; Sören Lehmann; Stacey B Gabriel; Jennifer L Moran; Eric S Lander; Patrick F Sullivan; Pamela Sklar; Henrik Grönberg; Christina M Hultman; Steven A McCarroll
Journal:  N Engl J Med       Date:  2014-11-26       Impact factor: 91.245

5.  Prognostic Mutations in Myelodysplastic Syndrome after Stem-Cell Transplantation.

Authors:  R Coleman Lindsley; Wael Saber; Brenton G Mar; Robert Redd; Tao Wang; Michael D Haagenson; Peter V Grauman; Zhen-Huan Hu; Stephen R Spellman; Stephanie J Lee; Michael R Verneris; Katharine Hsu; Katharina Fleischhauer; Corey Cutler; Joseph H Antin; Donna Neuberg; Benjamin L Ebert
Journal:  N Engl J Med       Date:  2017-02-09       Impact factor: 91.245

6.  Role of p53 in hematopoietic recovery after cytotoxic treatment.

Authors:  P Wlodarski; M Wasik; M Z Ratajczak; C Sevignani; G Hoser; J Kawiak; A M Gewirtz; B Calabretta; T Skorski
Journal:  Blood       Date:  1998-04-15       Impact factor: 22.113

7.  p53 regulates hematopoietic stem cell quiescence.

Authors:  Yan Liu; Shannon E Elf; Yasuhiko Miyata; Goro Sashida; Yuhui Liu; Gang Huang; Silvana Di Giandomenico; Jennifer M Lee; Anthony Deblasio; Silvia Menendez; Jack Antipin; Boris Reva; Andrew Koff; Stephen D Nimer
Journal:  Cell Stem Cell       Date:  2009-01-09       Impact factor: 24.633

8.  p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis.

Authors:  C J Kemp; T Wheldon; A Balmain
Journal:  Nat Genet       Date:  1994-09       Impact factor: 38.330

9.  p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.

Authors:  Hoseok Song; Monica Hollstein; Yang Xu
Journal:  Nat Cell Biol       Date:  2007-04-08       Impact factor: 28.824

Review 10.  Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer.

Authors:  Peter D Adams; Heinrich Jasper; K Lenhard Rudolph
Journal:  Cell Stem Cell       Date:  2015-06-04       Impact factor: 24.633
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  12 in total

1.  Pediatric ALL relapses after allo-SCT show high individuality, clonal dynamics, selective pressure, and druggable targets.

Authors:  Jessica I Hoell; Sebastian Ginzel; Michaela Kuhlen; Andreas Kloetgen; Michael Gombert; Ute Fischer; Daniel Hein; Salih Demir; Martin Stanulla; Martin Schrappe; Udo Zur Stadt; Peter Bader; Florian Babor; Friedhelm Schuster; Brigitte Strahm; Julia Alten; Anja Moericke; Gabriele Escherich; Arend von Stackelberg; Ralf Thiele; Alice C McHardy; Christina Peters; Beat Bornhauser; Jean-Pierre Bourquin; Stefan Krause; Juergen Enczmann; Lüder Hinrich Meyer; Cornelia Eckert; Arndt Borkhardt; Roland Meisel
Journal:  Blood Adv       Date:  2019-10-22

Review 2.  Exploring the Associations Between Clonal Hematopoiesis of Indeterminate Potential, Myeloid Malignancy, and Atherosclerosis.

Authors:  Juan Bautista Menendez-Gonzalez; Neil P Rodrigues
Journal:  Methods Mol Biol       Date:  2022

Review 3.  Importance of clonal hematopoiesis in heart failure.

Authors:  Nicholas W Chavkin; Kyung-Duk Min; Kenneth Walsh
Journal:  Trends Cardiovasc Med       Date:  2021-04-20       Impact factor: 6.677

4.  TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis.

Authors:  Madeline Niederkorn; Kathleen Hueneman; Kwangmin Choi; Melinda E Varney; Laurel Romano; Mario A Pujato; Kenneth D Greis; Jun-Ichiro Inoue; Ruhikanta Meetei; Daniel T Starczynowski
Journal:  Cell Rep       Date:  2020-02-25       Impact factor: 9.423

5.  Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation.

Authors:  Derek S Park; Afua A Akuffo; David E Muench; H Leighton Grimes; Pearlie K Epling-Burnette; Philip K Maini; Alexander R A Anderson; Michael B Bonsall
Journal:  PLoS Comput Biol       Date:  2019-04-26       Impact factor: 4.475

6.  TP53 mutated AML subclones exhibit engraftment in a humanized bone marrow ossicle mouse model.

Authors:  Gabriel Pabst; Karin Lind; Ricarda Graf; Armin Zebisch; Friedrich Stölzel; Konstanze Döhner; Ellen Heitzer; Andreas Reinisch; Heinz Sill
Journal:  Ann Hematol       Date:  2020-01-30       Impact factor: 3.673

7.  Mutant p53 enhances leukemia-initiating cell self-renewal to promote leukemia development.

Authors:  Sarah C Nabinger; Sisi Chen; Rui Gao; Chonghua Yao; Michihiro Kobayashi; Sasidhar Vemula; Aidan C Fahey; Christine Wang; Cecil Daniels; H Scott Boswell; George E Sandusky; Lindsey D Mayo; Reuben Kapur; Yan Liu
Journal:  Leukemia       Date:  2019-01-23       Impact factor: 12.883

8.  Clinical implications of subclonal TP53 mutations in acute myeloid leukemia.

Authors:  Katharina T Prochazka; Gudrun Pregartner; Frank G Rücker; Ellen Heitzer; Gabriel Pabst; Albert Wölfler; Armin Zebisch; Andrea Berghold; Konstanze Döhner; Heinz Sill
Journal:  Haematologica       Date:  2018-10-11       Impact factor: 9.941

9.  Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway.

Authors:  Sisi Chen; Qiang Wang; Hao Yu; Maegan L Capitano; Sasidhar Vemula; Sarah C Nabinger; Rui Gao; Chonghua Yao; Michihiro Kobayashi; Zhuangzhuang Geng; Aidan Fahey; Danielle Henley; Stephen Z Liu; Sergio Barajas; Wenjie Cai; Eric R Wolf; Baskar Ramdas; Zhigang Cai; Hongyu Gao; Na Luo; Yang Sun; Terrence N Wong; Daniel C Link; Yunlong Liu; H Scott Boswell; Lindsey D Mayo; Gang Huang; Reuben Kapur; Mervin C Yoder; Hal E Broxmeyer; Zhonghua Gao; Yan Liu
Journal:  Nat Commun       Date:  2019-12-11       Impact factor: 17.694

Review 10.  Fate of Hematopoiesis During Aging. What Do We Really Know, and What are its Implications?

Authors:  Hal E Broxmeyer; Yan Liu; Reuben Kapur; Christie M Orschell; Arafat Aljoufi; James P Ropa; Thao Trinh; Sarah Burns; Maegan L Capitano
Journal:  Stem Cell Rev Rep       Date:  2020-11-03       Impact factor: 5.739
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