Reyhaneh Yousefi1, Atoosa Saidpour2, Azadeh Mottaghi3. 1. M.Sc. in Nutrition, Preventive Medicine and Public Health Research Center, Iran University of Medical Sciences, Tehran, Iran. Electronic address: r.yousefi@sbmu.ac.ir. 2. Assistant Professor (PhD) of Nutrition, Department of Clinical Nutrition & Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: a.saidpour@sbmu.ac.ir. 3. Assistant Professor (PhD) of Nutrition, Research Center for Prevention of Cardiovascular Diseases, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran. Electronic address: Mottaghi.a@iums.ac.ir.
Abstract
AIMS: The aim of this systematic review was to assess the effects of Spirulina supplementation on metabolic syndrome components, its liver manifestation and related inflammatory markers. METHODS: We searched PubMed and Scopus (up to August 2017) to identify relevant studies. English randomized controlled trials (RCTs) investigating the effects of Spirulina supplementation on factors associated with metabolic syndrome in human models, were included in the review. RESULTS: Among 720 articles related to Spirulina in the primary search, 22 of them were eligible human RCTs and finally 18 of them were included in the review. The systematic review revealed that oral dosage range of 1-19gr/day for 0.5-6 months of Spirulina supplementation have positive effects on metabolic syndrome components. CONCLUSION: Spirulina can be possibly administered as a safe and efficient supplementation in the case of metabolic syndrome components, although determining the optimal dosage and period of supplementation still needs further investigations.
AIMS: The aim of this systematic review was to assess the effects of Spirulina supplementation on metabolic syndrome components, its liver manifestation and related inflammatory markers. METHODS: We searched PubMed and Scopus (up to August 2017) to identify relevant studies. English randomized controlled trials (RCTs) investigating the effects of Spirulina supplementation on factors associated with metabolic syndrome in human models, were included in the review. RESULTS: Among 720 articles related to Spirulina in the primary search, 22 of them were eligible human RCTs and finally 18 of them were included in the review. The systematic review revealed that oral dosage range of 1-19gr/day for 0.5-6 months of Spirulina supplementation have positive effects on metabolic syndrome components. CONCLUSION: Spirulina can be possibly administered as a safe and efficient supplementation in the case of metabolic syndrome components, although determining the optimal dosage and period of supplementation still needs further investigations.