Ilker Gül1, Levent Cerit1, Bihter Senturk2, Mustafa Zungur3, Mustafa Beyazıt Alkan4, Hatice Kemal1, Zeynep Cerit5, Belma Yaman1, Songul Usalp1, Hamza Duygu1. 1. Near East University, Faculty of Medicine, Department of Cardiology, Nicosia, Cyprus. 2. Dokuz Eylül University, Faculty of Medicine, Department of Cardiology, Izmir, Turkey. 3. Kent Hospital, Cardiology Clinic, Izmir, Turkey. 4. Kas State Hospital, Antalya, Turkey. 5. Near East University, Faculty of Medicine, Department of Pediatric Cardiology, Nicosia, Cyprus.
Abstract
OBJECTIVE: To evaluate the predictive value of mean perfusion pressure (mPP) in the development of acute kidney injury (AKIN) after transcatheter aortic valve implantation (TAVI). METHODS: One hundred and forty seven consecutive patients with aortic stenosis (AS) were evaluated for this study and 133 of them were included. Mean arterial pressure (mAP) and central venous pressure (CVP) were used to calculate mPP before TAVI procedure (mPP = mAP-CVP). The occurrence of AKIN was evaluated with AKIN classification according to the Valve Academic Research Consortium-2 recommendations. The patients were divided into two groups according to the receiver operating characteristic (ROC) analysis of their mPP levels (high-risk group and low-risk group). RESULTS: The AKIN prevalence was 22.6% in this study population. Baseline serum creatinine level, glomerular filtration rate, amount of contrast medium, and the level of mPP were determined as predictive factors for the development of AKIN. CONCLUSION: The occurrence of AKIN is associated with increased morbidity and mortality rates in patients with TAVI. In addition to the amount of contrast medium and basal kidney functions, our study showed that lower mPP was strongly associated with development of AKIN after TAVI.
OBJECTIVE: To evaluate the predictive value of mean perfusion pressure (mPP) in the development of acute kidney injury (AKIN) after transcatheter aortic valve implantation (TAVI). METHODS: One hundred and forty seven consecutive patients with aortic stenosis (AS) were evaluated for this study and 133 of them were included. Mean arterial pressure (mAP) and central venous pressure (CVP) were used to calculate mPP before TAVI procedure (mPP = mAP-CVP). The occurrence of AKIN was evaluated with AKIN classification according to the Valve Academic Research Consortium-2 recommendations. The patients were divided into two groups according to the receiver operating characteristic (ROC) analysis of their mPP levels (high-risk group and low-risk group). RESULTS: The AKIN prevalence was 22.6% in this study population. Baseline serum creatinine level, glomerular filtration rate, amount of contrast medium, and the level of mPP were determined as predictive factors for the development of AKIN. CONCLUSION: The occurrence of AKIN is associated with increased morbidity and mortality rates in patients with TAVI. In addition to the amount of contrast medium and basal kidney functions, our study showed that lower mPP was strongly associated with development of AKIN after TAVI.
Authors: George Dangas; Ioannis Iakovou; Eugenia Nikolsky; Eve D Aymong; Gary S Mintz; Nicholas N Kipshidze; Alexandra J Lansky; Issam Moussa; Gregg W Stone; Jeffrey W Moses; Martin B Leon; Roxana Mehran Journal: Am J Cardiol Date: 2005-01-01 Impact factor: 2.778
Authors: Rutger-Jan Nuis; Josep Rodés-Cabau; Jan-Malte Sinning; Leen van Garsse; Joelle Kefer; Johan Bosmans; Antonio E Dager; Nicolas van Mieghem; Marina Urena; Georg Nickenig; Nikos Werner; Jos Maessen; Parla Astarci; Sergio Perez; Luis M Benitez; Eric Dumont; Ron T van Domburg; Peter P de Jaegere Journal: Circ Cardiovasc Interv Date: 2012-10-09 Impact factor: 6.546
Authors: Rodrigo Bagur; John G Webb; Fabian Nietlispach; Eric Dumont; Robert De Larochellière; Daniel Doyle; Jean-Bernard Masson; Marcos J Gutiérrez; Marie-Annick Clavel; Olivier F Bertrand; Philippe Pibarot; Josep Rodés-Cabau Journal: Eur Heart J Date: 2009-12-27 Impact factor: 29.983