Literature DB >> 3064356

Luminography--an alternative assay for detection of von Willebrand factor multimers.

R Schneppenheim1, H Plendl, U Budde.   

Abstract

A luminescence assay was adapted for detection of von Willebrand factor multimers subsequent to SDS-agarose gel electrophoresis and electroblotting onto nitrocellulose. The method is as fast as chromogenic detection methods and appears to be as sensitive as autoradiography without the disadvantages of the latter.

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Year:  1988        PMID: 3064356

Source DB:  PubMed          Journal:  Thromb Haemost        ISSN: 0340-6245            Impact factor:   5.249


  14 in total

1.  Shear-Induced Unfolding and Enzymatic Cleavage of Full-Length VWF Multimers.

Authors:  Svenja Lippok; Matthias Radtke; Tobias Obser; Lars Kleemeier; Reinhard Schneppenheim; Ulrich Budde; Roland R Netz; Joachim O Rädler
Journal:  Biophys J       Date:  2016-02-02       Impact factor: 4.033

2.  The mutation N528S in the von Willebrand factor (VWF) propeptide causes defective multimerization and storage of VWF.

Authors:  Sandra L Haberichter; Ulrich Budde; Tobias Obser; Sonja Schneppenheim; Cornelia Wermes; Reinhard Schneppenheim
Journal:  Blood       Date:  2010-03-24       Impact factor: 22.113

3.  Mutation G1629E Increases von Willebrand Factor Cleavage via a Cooperative Destabilization Mechanism.

Authors:  Camilo Aponte-Santamaría; Svenja Lippok; Judith J Mittag; Tobias Obser; Reinhard Schneppenheim; Carsten Baldauf; Frauke Gräter; Ulrich Budde; Joachim O Rädler
Journal:  Biophys J       Date:  2017-01-10       Impact factor: 4.033

4.  Exponential size distribution of von Willebrand factor.

Authors:  Svenja Lippok; Tobias Obser; Jochen P Müller; Valentin K Stierle; Martin Benoit; Ulrich Budde; Reinhard Schneppenheim; Joachim O Rädler
Journal:  Biophys J       Date:  2013-09-03       Impact factor: 4.033

5.  Defective dimerization of von Willebrand factor subunits due to a Cys-> Arg mutation in type IID von Willebrand disease.

Authors:  R Schneppenheim; J Brassard; S Krey; U Budde; T J Kunicki; L Holmberg; J Ware; Z M Ruggeri
Journal:  Proc Natl Acad Sci U S A       Date:  1996-04-16       Impact factor: 11.205

6.  Analysis of von Willebrand factor multimers using a commercially available enhanced chemiluminescence kit.

Authors:  A M Cumming; R T Wensley
Journal:  J Clin Pathol       Date:  1993-05       Impact factor: 3.411

7.  Functional analysis of a type IIB von Willebrand disease missense mutation: increased binding of large von Willebrand factor multimers to platelets.

Authors:  K A Cooney; S E Lyons; D Ginsburg
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-01       Impact factor: 11.205

8.  Identification of type 1 von Willebrand disease patients with reduced von Willebrand factor survival by assay of the VWF propeptide in the European study: molecular and clinical markers for the diagnosis and management of type 1 VWD (MCMDM-1VWD).

Authors:  Sandra L Haberichter; Giancarlo Castaman; Ulrich Budde; Ian Peake; Anne Goodeve; Francesco Rodeghiero; Augusto B Federici; Javier Batlle; Dominique Meyer; Claudine Mazurier; Jenny Goudemand; Jeroen Eikenboom; Reinhard Schneppenheim; Jorgen Ingerslev; Zdena Vorlova; David Habart; Lars Holmberg; Stefan Lethagen; John Pasi; Frank G H Hill; Robert R Montgomery
Journal:  Blood       Date:  2008-03-14       Impact factor: 22.113

9.  Identification and characterization of the elusive mutation causing the historical von Willebrand Disease type IIC Miami.

Authors:  T Obser; M Ledford-Kraemer; F Oyen; M A Brehm; C V Denis; R Marschalek; R R Montgomery; J E Sadler; S Schneppenheim; U Budde; R Schneppenheim
Journal:  J Thromb Haemost       Date:  2016-08-20       Impact factor: 5.824

10.  Genetic heterogeneity of severe von Willebrand disease type III in the German population.

Authors:  R Schneppenheim; S Krey; F Bergmann; D Bock; U Budde; M Lange; R Linde; U Mittler; E Meili; G Mertes
Journal:  Hum Genet       Date:  1994-12       Impact factor: 4.132

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