Literature DB >> 30630829

Mapping Physical Tumor Microenvironment and Drug Delivery.

Hadi T Nia1, Lance L Munn1, Rakesh K Jain2.   

Abstract

The physical microenvironment of pancreatic tumors is highly abnormal, and this causes significant challenges for drug delivery through multiple mechanisms. Measurements of tissue elasticity could be used as a physical biomarker to assess aberrant drug delivery, and potentially guide stroma-targeting treatment strategies and patient stratification.See related article by Wang et al., p. 2136. ©2019 American Association for Cancer Research.

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Year:  2019        PMID： 30630829      PMCID： PMC6445672          DOI： 10.1158/1078-0432.CCR-18-3724

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   12.531


  5 in total

1.  Role of extracellular matrix assembly in interstitial transport in solid tumors.

Authors:  P A Netti; D A Berk; M A Swartz; A J Grodzinsky; R K Jain
Journal:  Cancer Res       Date:  2000-05-01       Impact factor: 12.701

2.  Elastography Can Map the Local Inverse Relationship between Shear Modulus and Drug Delivery within the Pancreatic Ductal Adenocarcinoma Microenvironment.

Authors:  Hexuan Wang; Reem Mislati; Rifat Ahmed; Phuong Vincent; Solumtochukwu F Nwabunwanne; Jason R Gunn; Brian W Pogue; Marvin M Doyley
Journal:  Clin Cancer Res       Date:  2018-10-23       Impact factor: 12.531

Review 3.  The role of mechanical forces in tumor growth and therapy.

Authors:  Rakesh K Jain; John D Martin; Triantafyllos Stylianopoulos
Journal:  Annu Rev Biomed Eng       Date:  2014-07-11       Impact factor: 9.590

4.  Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels.

Authors:  Vikash P Chauhan; John D Martin; Hao Liu; Delphine A Lacorre; Saloni R Jain; Sergey V Kozin; Triantafyllos Stylianopoulos; Ahmed S Mousa; Xiaoxing Han; Pichet Adstamongkonkul; Zoran Popović; Peigen Huang; Moungi G Bawendi; Yves Boucher; Rakesh K Jain
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

5.  Solid stress and elastic energy as measures of tumour mechanopathology.

Authors:  Hadi T Nia; Hao Liu; Giorgio Seano; Meenal Datta; Dennis Jones; Nuh Rahbari; Joao Incio; Vikash P Chauhan; Keehoon Jung; John D Martin; Vasileios Askoxylakis; Timothy P Padera; Dai Fukumura; Yves Boucher; Francis J Hornicek; Alan J Grodzinsky; James W Baish; Lance L Munn; Rakesh K Jain
Journal:  Nat Biomed Eng       Date:  2016-11-28       Impact factor: 25.671
  5 in total
  9 in total

1.  Enhancing carrier flux for efficient drug delivery in cancer tissues.

Authors:  Andrés Arango-Restrepo; J Miguel Rubi; Signe Kjelstrup; Bjørn Atle J Angelsen; Catharina de Lange Davies
Journal:  Biophys J       Date:  2021-10-30       Impact factor: 4.033

2.  The Unfolded Protein Response Sensor PERK Mediates Stiffness-Dependent Adaptation in Glioblastoma Cells.

Authors:  Mohammad Khoonkari; Dong Liang; Marina Trombetta Lima; Tjitze van der Land; Yuanke Liang; Jianwu Sun; Amalia Dolga; Marleen Kamperman; Patrick van Rijn; Frank A E Kruyt
Journal:  Int J Mol Sci       Date:  2022-06-10       Impact factor: 6.208

Review 3.  Reciprocity of Cell Mechanics with Extracellular Stimuli: Emerging Opportunities for Translational Medicine.

Authors:  Yiwei Li; Ian Y Wong; Ming Guo
Journal:  Small       Date:  2022-03-23       Impact factor: 15.153

Review 4.  Physics of Brain Cancer: Multiscale Alterations of Glioblastoma Cells under Extracellular Matrix Stiffening.

Authors:  Mohammad Khoonkari; Dong Liang; Marleen Kamperman; Frank A E Kruyt; Patrick van Rijn
Journal:  Pharmaceutics       Date:  2022-05-10       Impact factor: 6.525

5.  Preclinical Imaging Using Single Track Location Shear Wave Elastography: Monitoring the Progression of Murine Pancreatic Tumor Liver Metastasis In Vivo.

Authors:  Rifat Ahmed; Jian Ye; Scott A Gerber; David C Linehan; Marvin M Doyley
Journal:  IEEE Trans Med Imaging       Date:  2020-02-03       Impact factor: 10.048

Review 6.  Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies.

Authors:  Luman Liu; Prakash G Kshirsagar; Shailendra K Gautam; Mansi Gulati; Emad I Wafa; John C Christiansen; Brianna M White; Surya K Mallapragada; Michael J Wannemuehler; Sushil Kumar; Joyce C Solheim; Surinder K Batra; Aliasger K Salem; Balaji Narasimhan; Maneesh Jain
Journal:  Theranostics       Date:  2022-01-01       Impact factor: 11.600

7.  Longitudinal Monitoring of Simulated Interstitial Fluid Pressure for Pancreatic Ductal Adenocarcinoma Patients Treated with Stereotactic Body Radiotherapy.

Authors:  Ramesh Paudyal; Eve LoCastro; Marsha Reyngold; Richard Kinh Do; Amaresha Shridhar Konar; Jung Hun Oh; Abhay Dave; Kenneth Yu; Karyn A Goodman; Amita Shukla-Dave
Journal:  Cancers (Basel)       Date:  2021-08-26       Impact factor: 6.639

Review 8.  Integration of Genomic Biology Into Therapeutic Strategies of Gastric Cancer Peritoneal Metastasis.

Authors:  Yong Xiang Gwee; Daryl Kai Ann Chia; Jimmy So; Wim Ceelen; Wei Peng Yong; Patrick Tan; Chin-Ann Johnny Ong; Raghav Sundar
Journal:  J Clin Oncol       Date:  2022-06-01       Impact factor: 50.717

9.  Glutathione Pulse Therapy: Promote Spatiotemporal Delivery of Reduction-Sensitive Nanoparticles at the "Cellular Level" and Synergize PD-1 Blockade Therapy.

Authors:  Songtao Dong; Yuan Zhang; Xiangnan Guo; Chuang Zhang; Zhaomeng Wang; Jiang Yu; Yubo Liu; Chang Li; Yuting Hu; Bingjun Sun; Mengchi Sun; Haotian Zhang; Defang Ouyang; Zhonggui He; Yongjun Wang
Journal:  Adv Sci (Weinh)       Date:  2022-07-27       Impact factor: 17.521
  9 in total

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