Literature DB >> 3062576

Cloning and characterization of the Saccharomyces cerevisiae CDC6 gene.

J Lisziewicz1, A Godany, D V Agoston, H Küntzel.   

Abstract

The yeast cell division cycle gene CDC6 was isolated by complementation of a temperature-sensitive cdc6 mutant with a genomic library. The amino acid sequence of the 48 kDalton CDC6 gene product, as deduced from DNA sequence data, includes the three consensus peptide motifs involved in guanine nucleotide binding and GTPase activity, a target site for cAMP-dependent protein kinase and a carboxy-terminal domain related to metallothionein sequences. A plasmid-encoded CDC6-beta-galactosidase hybrid protein was located at the plasma membrane by indirect immunofluorescence. Disruption experiments indicate that the CDC6 gene product is essential for mitotic growth.

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Year:  1988        PMID： 3062576      PMCID： PMC339061          DOI： 10.1093/nar/16.24.11507

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  34 in total

1.  Repetitive segmental structure of the transducin beta subunit: homology with the CDC4 gene and identification of related mRNAs.

Authors:  H K Fong; J B Hurley; R S Hopkins; R Miake-Lye; M S Johnson; R F Doolittle; M I Simon
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

2.  Three-dimensional structure of an oncogene protein: catalytic domain of human c-H-ras p21.

Authors:  A M de Vos; L Tong; M V Milburn; P M Matias; J Jancarik; S Noguchi; S Nishimura; K Miura; E Ohtsuka; S H Kim
Journal:  Science       Date:  1988-02-19       Impact factor: 47.728

3.  Three additional genes required for deoxyribonucleic acid synthesis in Saccharomyces cerevisiae.

Authors:  L H Hartwell
Journal:  J Bacteriol       Date:  1973-09       Impact factor: 3.490

4.  Genetic Control of the Cell Division Cycle in Yeast: V. Genetic Analysis of cdc Mutants.

Authors:  L H Hartwell; R K Mortimer; J Culotti; M Culotti
Journal:  Genetics       Date:  1973-06       Impact factor: 4.562

5.  Mammalian keratin gene families: organisation of genes coding for the B2 high-sulphur proteins of sheep wool.

Authors:  B C Powell; M J Sleigh; K A Ward; G E Rogers
Journal:  Nucleic Acids Res       Date:  1983-08-25       Impact factor: 16.971

6.  Beta-galactosidase gene fusions for analyzing gene expression in escherichia coli and yeast.

Authors:  M J Casadaban; A Martinez-Arias; S K Shapira; J Chou
Journal:  Methods Enzymol       Date:  1983       Impact factor: 1.600

7.  A simple method for displaying the hydropathic character of a protein.

Authors:  J Kyte; R F Doolittle
Journal:  J Mol Biol       Date:  1982-05-05       Impact factor: 5.469

8.  Molecular characterization of cell cycle gene CDC7 from Saccharomyces cerevisiae.

Authors:  M Patterson; R A Sclafani; W L Fangman; J Rosamond
Journal:  Mol Cell Biol       Date:  1986-05       Impact factor: 4.272

9.  Isolation of a second yeast Saccharomyces cerevisiae gene (GPA2) coding for guanine nucleotide-binding regulatory protein: studies on its structure and possible functions.

Authors:  M Nakafuku; T Obara; K Kaibuchi; I Miyajima; A Miyajima; H Itoh; S Nakamura; K Arai; K Matsumoto; Y Kaziro
Journal:  Proc Natl Acad Sci U S A       Date:  1988-03       Impact factor: 11.205

10.  Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces.

Authors:  J V Kilmartin; A E Adams
Journal:  J Cell Biol       Date:  1984-03       Impact factor: 10.539
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  13 in total

1.  Genetic and sequence organization of the mcrBC locus of Escherichia coli K-12.

Authors:  D Dila; E Sutherland; L Moran; B Slatko; E A Raleigh
Journal:  J Bacteriol       Date:  1990-09       Impact factor: 3.490

2.  Temperature-sensitive cdc7 mutations of Saccharomyces cerevisiae are suppressed by the DBF4 gene, which is required for the G1/S cell cycle transition.

Authors:  K Kitada; L H Johnston; T Sugino; A Sugino
Journal:  Genetics       Date:  1992-05       Impact factor: 4.562

3.  Xenopus Cdc6 confers sperm binding competence to oocytes without inducing their maturation.

Authors:  J Tian; G H Thomsen; H Gong; W J Lennarz
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-30       Impact factor: 11.205

Review 4.  Mechanisms and regulation of DNA replication initiation in eukaryotes.

Authors:  Matthew W Parker; Michael R Botchan; James M Berger
Journal:  Crit Rev Biochem Mol Biol       Date:  2017-01-17       Impact factor: 8.250

5.  Addition of extra origins of replication to a minichromosome suppresses its mitotic loss in cdc6 and cdc14 mutants of Saccharomyces cerevisiae.

Authors:  E Hogan; D Koshland
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-01       Impact factor: 11.205

6.  Gene products that promote mRNA turnover in Saccharomyces cerevisiae.

Authors:  P Leeds; J M Wood; B S Lee; M R Culbertson
Journal:  Mol Cell Biol       Date:  1992-05       Impact factor: 4.272

7.  The role of Saccharomyces cerevisiae Cdc40p in DNA replication and mitotic spindle formation and/or maintenance.

Authors:  N Vaisman; A Tsouladze; K Robzyk; S Ben-Yehuda; M Kupiec; Y Kassir
Journal:  Mol Gen Genet       Date:  1995-04-20

Review 8.  Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae.

Authors:  M D Mendenhall; A E Hodge
Journal:  Microbiol Mol Biol Rev       Date:  1998-12       Impact factor: 11.056

9.  Negative regulation of G1 and G2 by S-phase cyclins of Saccharomyces cerevisiae.

Authors:  R D Basco; M D Segal; S I Reed
Journal:  Mol Cell Biol       Date:  1995-09       Impact factor: 4.272

10.  Mutations in subdomain B of the minichromosome maintenance (MCM) helicase affect DNA binding and modulate conformational transitions.

Authors:  Elizabeth R Jenkinson; Alessandro Costa; Andrew P Leech; Ardan Patwardhan; Silvia Onesti; James P J Chong
Journal:  J Biol Chem       Date:  2008-12-30       Impact factor: 5.157
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