Literature DB >> 30624351

A Dosimetry Study of Portable X-ray Fluorescence in Vivo Metal Measurements.

Aaron J Specht1, Xinxin Zhang2, Benjamin D Goodman3, Ed Maher1, Marc G Weisskopf1, Linda H Nie2.   

Abstract

Portable x-ray fluorescence devices have grown in popularity for possible metal exposure assessment using in vivo measurements of bone and toenail. These measurements are accompanied by a small radiation dose, which is typically assessed by radiation safety committees to be minimal. However, an understanding of precise dose under different instrument conditions is still needed. This study set out to do a thorough investigation of the exact dose measurements using optically stimulated dosimeters, thermoluminescent dosimeters, and simulation with a Monte Carlo N-Particle transport code to assess the skin and total-body effective dose typical of portable x-ray fluorescence devices. We showed normal linear relationships between measurement time, x-ray tube current, and radiation dose with the device, and we showed a second order polynomial relationship with increasing voltage and radiation dose. Dose was quantified using thermoluminescent dosimeters, optically stimulated dosimeters, and simulations, which gave similar dose estimations. Skin dose for a standard 50-kV, 40-μA measurement for bone and toenail in vivo was 48.5 and 28.7 mSv, respectively, according to simulation results. Total-body effective dose was shown as 3.4 and 2.0 μSv for in vivo bone and toenail measurements, respectively, for adults using the portable x-ray fluorescence device.

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Year:  2019        PMID: 30624351      PMCID: PMC6433501          DOI: 10.1097/HP.0000000000000971

Source DB:  PubMed          Journal:  Health Phys        ISSN: 0017-9078            Impact factor:   2.922


  18 in total

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Journal:  Phys Med Biol       Date:  2010-02-24       Impact factor: 3.609

4.  The dose-survival relationship for irradiation of epithelial cells of mouse skin.

Authors:  H R Withers
Journal:  Br J Radiol       Date:  1967-03       Impact factor: 3.039

5.  In vivo quantification of lead in bone with a portable x-ray fluorescence system--methodology and feasibility.

Authors:  L H Nie; S Sanchez; K Newton; L Grodzins; R O Cleveland; M G Weisskopf
Journal:  Phys Med Biol       Date:  2011-01-17       Impact factor: 3.609

6.  Quantification of manganese and mercury in toenail in vivo using portable X-ray fluorescence (XRF).

Authors:  Xinxin Zhang; Aaron J Specht; Marc G Weisskopf; Jennifer Weuve; Linda H Nie
Journal:  Biomarkers       Date:  2017-10-10       Impact factor: 2.658

7.  Basic anatomical and physiological data for use in radiological protection: reference values. A report of age- and gender-related differences in the anatomical and physiological characteristics of reference individuals. ICRP Publication 89.

Authors: 
Journal:  Ann ICRP       Date:  2002

8.  Total body bone area, bone mineral content, and bone mineral density for individuals aged 8 years and over: United States, 1999-2006.

Authors:  Anne C Looker; Lori G Borrud; Jeffery P Hughes; Bo Fan; John A Shepherd; Mary Sherman
Journal:  Vital Health Stat 11       Date:  2013-08

9.  On the Use of Optically Stimulated Luminescent Dosimeter for Surface Dose Measurement during Radiotherapy.

Authors:  Fasihah Hanum Yusof; Ngie Min Ung; Jeannie Hsiu Ding Wong; Wei Loong Jong; Vannyat Ath; Vincent Chee Ee Phua; Siew Ping Heng; Kwan Hoong Ng
Journal:  PLoS One       Date:  2015-06-08       Impact factor: 3.240

10.  Portable XRF Technology to Quantify Pb in Bone In Vivo.

Authors:  Aaron James Specht; Marc Weisskopf; Linda Huiling Nie
Journal:  J Biomark       Date:  2014-11-27
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  2 in total

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Journal:  Pregnancy Hypertens       Date:  2020-07-31       Impact factor: 2.899

2.  Validation of in vivo toenail measurements of manganese and mercury using a portable X-ray fluorescence device.

Authors:  Jennifer Weuve; Linda H Nie; Marc G Weisskopf; Aaron J Specht; Xinxin Zhang; Anna Young; Vy T Nguyen; David C Christiani; Diana M Ceballos; Joseph G Allen
Journal:  J Expo Sci Environ Epidemiol       Date:  2021-07-01       Impact factor: 5.563

  2 in total

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