Literature DB >> 3061868

A resolution of the ascertainment sampling problem: IV. Continuous phenotypes.

W J Ewens1, R M Green.   

Abstract

This paper considers ascertainment corrections for continuous phenotypes. Two main points are considered. The first is a discussion of what ascertainment corrections can be devised to ensure asymptotically unbiased parameter estimates when the nature of the ascertainment procedure is not known. The second is an analysis of the properties of various forms of ascertainment correction possible when the nature of the ascertainment procedure is known. Some ascertainment corrections are thus shown to be valid and others invalid.

Mesh:

Year:  1988        PMID: 3061868     DOI: 10.1002/gepi.1370050607

Source DB:  PubMed          Journal:  Genet Epidemiol        ISSN: 0741-0395            Impact factor:   2.135


  3 in total

1.  A cooperative binomial ascertainment model.

Authors:  E Kh Ginsburg; T I Axenovich
Journal:  Am J Hum Genet       Date:  1992-11       Impact factor: 11.025

2.  The essence of single ascertainment.

Authors:  S E Hodge; V J Vieland
Journal:  Genetics       Date:  1996-11       Impact factor: 4.562

3.  Genetic investigation of quantitative traits related to autism: use of multivariate polygenic models with ascertainment adjustment.

Authors:  Yun Ju Sung; Geraldine Dawson; Jeffrey Munson; Annette Estes; Gerard D Schellenberg; Ellen M Wijsman
Journal:  Am J Hum Genet       Date:  2004-11-16       Impact factor: 11.025

  3 in total

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