| Literature DB >> 30616916 |
Andrés E Ortiz-Flores1, Manuel Luque-Ramírez1, Héctor F Escobar-Morreale2.
Abstract
Polycystic ovary syndrome is the most prevalent endocrine-metabolic pathology in pre-menopausal women. Its etiopathogenesis is complex, multifactorial and heterogeneous, including the interaction of genetic, epigenetic and environmental factors. Androgenic excess constitutes the disease's main physiopathological mechanism and results in reproductive, metabolic and cosmetic alterations which negatively impact these patients' quality of life. The criteria established in the Rotterdam consensus and their correct application form the necessary basis for this syndrome's proper diagnosis. In the absence of an aetiological treatment, the aim is to improve the clinical signs and symptoms derived from hyperandrogenism, ovarian dysfunction and existing metabolic complications, and, therefore, they must be chronic and individualised.Entities:
Keywords: Disfunción ovulatoria; Hiperandrogenismo; Hyperandrogenism; Obesidad; Obesity; Ovulatory dysfunction; Subfertilidad; Subfertility
Year: 2019 PMID: 30616916 DOI: 10.1016/j.medcli.2018.11.019
Source DB: PubMed Journal: Med Clin (Barc) ISSN: 0025-7753 Impact factor: 1.725