| Literature DB >> 30612654 |
Zuokai Wang1, Liu Wu1, Yawei Wang1, Meng Zhang1, Ziyang Zhao1, Caiyun Liu2, Qingxia Duan1, Pan Jia1, Baocun Zhu3.
Abstract
In this work, taking full advantage of the intramolecular charge transfer (ICT) mechanism, a hydroxynaphthalimide-based ratiometric two-photon fluorescent probe RTP-PN was synthesized to detect ONOO-. Probe RTP-PN could accurately detect ONOO- in the range of 1.4 nM-1.4 μM with the detection limit of 1.4 nM by a ratiometric fluorescence spectroscopy method. Additionally, probe RTP-PN exhibited an ultrafast response for ONOO- than other various species including H2O2 and ClO-. Finally, probe RTP-PN was successfully adopted to detect intracellular ONOO- by the two-photon excitation microscopy.Entities:
Keywords: Fluorescent probe; Hydroxynaphthalimide; Peroxynitrite (ONOO(−)); Ratiometric detection; Two-photon bioimaging
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Year: 2018 PMID： 30612654 DOI： 10.1016/j.aca.2018.05.064
Source DB: PubMed Journal: Anal Chim Acta ISSN： 0003-2670 Impact factor: 6.558