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Literature DB >> 30606501

Phage Display: An Overview in Context to Drug Discovery.

Selena Mimmi¹, Domenico Maisano¹, Ileana Quinto¹, Enrico Iaccino².

Abstract

Peptides are emerging as a new reliable class of therapeutics and, thanks to their lower cost of production, they are becoming established as perfect drug aspirants. Here, we briefly review the phage display method and its contribution to the identification of peptides of interest for the therapeutic market.

Keywords: drug discovery; peptides; phage display

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Substances：

Year: 2018 PMID： 30606501 DOI： 10.1016/j.tips.2018.12.005

Source DB: PubMed Journal: Trends Pharmacol Sci ISSN： 0165-6147 Impact factor: 14.819

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Cited

19 in total

1. Alternative use of phage display: phage M13 can remain viable in the intestines of poultry without causing damage.

Authors: Fabiana de Almeida Araújo Santos; Edson Campos Valadares Junior; Luiz Ricardo Goulart; Pedro Lucas Figueiredo Nunes; Eliane Pereira Mendonça; Lúcio Vilela Carneiro Girão; Aline Santana da Hora; Thatiana Bragine Ferreira; Luciana Machado Bastos; Alessandra Aparecida Medeiros-Ronchi; Belchiolina Beatriz Fonseca
Journal: AMB Express Date: 2022-06-02 Impact factor: 4.126

Phage Display: An Overview in Context to Drug Discovery.

1. Alternative use of phage display: phage M13 can remain viable in the intestines of poultry without causing damage.

2. Improvements in the production of purified M13 bacteriophage bio-nanoparticle.

3. A screened PirB antagonist peptide antagonizes Aβ₄₂-mediated inhibition of neurite outgrowth in vitro.

4. SARS-CoV-2 neutralizing antibody development strategies.

5. Miniaturised interaction proteomics on a microfluidic platform with ultra-low input requirements.

Review 6. Discovery of Antivirals Using Phage Display.

7. The optimization system for preparation of TG1 competent cells and electrotransformation.

8. A High-Throughput Single-Clone Phage Fluorescence Microwell Immunoassay and Laser-Driven Clonal Retrieval System.

Review 9. Plant/Bacterial Virus-Based Drug Discovery, Drug Delivery, and Therapeutics.

10. Evolution of a Landscape Phage Library in a Mouse Xenograft Model of Human Breast Cancer.