Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Engineering microbial membranes to increase stress tolerance of industrial strains.

Literature DB >> 30605774

Engineering microbial membranes to increase stress tolerance of industrial strains.

Yanli Qi¹, Hui Liu¹, Xiulai Chen¹, Liming Liu².

Abstract

The microbial membrane serves as a biological barrier that separates the interior of cells from the external environment, thus playing an important role in tolerance to stress conditions during industrial bioprocessing. Accordingly, engineering or regulation of membrane functions provides a great opportunity to improve the robustness of industrial strains and may enable increased titers, yield, and production of the targeted metabolites. In this review, we summarize the recent progress in metabolic engineering strategies to enhance membrane integrity, regulate membrane fluidity, and tune membrane permeability.

Keywords: Membrane fluidity; Membrane integrity; Membrane permeability; Metabolic engineering strategy; Microbial membrane

Mesh：

Year: 2018 PMID： 30605774 DOI： 10.1016/j.ymben.2018.12.010

Source DB: PubMed Journal: Metab Eng ISSN： 1096-7176 Impact factor: 9.783

Keyword Cloud
Cited

23 in total

Review 1. Recent advances of pH homeostasis mechanisms in Corynebacterium glutamicum.

Authors: Jing Guo; Zhenping Ma; Jinshan Gao; Jinhua Zhao; Liang Wei; Jun Liu; Ning Xu
Journal: World J Microbiol Biotechnol Date: 2019-11-26 Impact factor: 3.312

Review 2. The emergence of adaptive laboratory evolution as an efficient tool for biological discovery and industrial biotechnology.

Authors: Troy E Sandberg; Michael J Salazar; Liam L Weng; Bernhard O Palsson; Adam M Feist
Journal: Metab Eng Date: 2019-08-08 Impact factor: 9.783

3. Reverse engineering of fatty acid-tolerant Escherichia coli identifies design strategies for robust microbial cell factories.

Authors: Yingxi Chen; Erin E Boggess; Efrain Rodriguez Ocasio; Aric Warner; Lucas Kerns; Victoria Drapal; Chloe Gossling; Wilma Ross; Richard L Gourse; Zengyi Shao; Julie Dickerson; Thomas J Mansell; Laura R Jarboe
Journal: Metab Eng Date: 2020-05-28 Impact factor: 9.783

4. Mediator Engineering of Saccharomyces cerevisiae To Improve Multidimensional Stress Tolerance.

Authors: Yanli Qi; Nan Xu; Zehong Li; Jiaping Wang; Xin Meng; Cong Gao; Jian Chen; Wei Chen; Xiulai Chen; Liming Liu
Journal: Appl Environ Microbiol Date: 2022-04-04 Impact factor: 5.005

5. High production of triterpenoids in Yarrowia lipolytica through manipulation of lipid components.

Authors: Jin-Lai Zhang; Qiu-Yan Bai; Yang-Zi Peng; Jie Fan; Cong-Cong Jin; Ying-Xiu Cao; Ying-Jin Yuan
Journal: Biotechnol Biofuels Date: 2020-07-29 Impact factor: 6.040

Review 6. Stress modulation as a means to improve yeasts for lignocellulose bioconversion.

Authors: B A Brandt; T Jansen; H Volschenk; J F Görgens; W H Van Zyl; R Den Haan
Journal: Appl Microbiol Biotechnol Date: 2021-06-07 Impact factor: 4.813

7. Adaptive Laboratory Evolution of Halomonas bluephagenesis Enhances Acetate Tolerance and Utilization to Produce Poly(3-hydroxybutyrate).

Authors: Jing Zhang; Biao Jin; Jing Fu; Zhiwen Wang; Tao Chen
Journal: Molecules Date: 2022-05-08 Impact factor: 4.411