Literature DB >> 30603642

Unstable angina: trends and characteristics associated with length of hospitalization in the face of diminishing frequency-an evidence of a paradigm shift.

Aaqib H Malik1, Nauman Siddiqui2, Wilbert S Aronow1.   

Abstract

BACKGROUND: Unstable angina (UA) has been one of the most common presentations of acute coronary syndrome. The numbers of admitted UA patients have been diminishing in the recent past. However, we are seeing higher costs and higher length of inpatient stay. We attempt to identify the trends and characteristics of length of hospitalization in patients admitted with UA using a nationally representative dataset.
METHODS: We used the nationwide inpatient sample (NIS) from 2002-2014 to assess the factors associated with length of stay in patients admitted with unstable angina using ICD-9-CM primary diagnosis codes (411.1, 411.81, and 411.89). All variables pertaining to hospitalization were compared across the 3 groups based on varied length of hospital stay.
RESULTS: A total of 131,601 patients were admitted with the diagnosis of UA. The length of inpatient stay was ≤1 day, 2-6 days, and ≥7 days in 60,309 (45.83%), 67,291 (51.13%), and 4,001 (3.05%) patients, respectively. In a multivariate adjusted model, the percentage increased odds of ≥2 days of inpatient stay was noted as follows: age ≥65 years (29%), female gender(24%), African-American race (28%), obesity (14%), diabetes mellitus (15%), chronic lung disease (33%), congestive heart failure (529%), renal failure (26%), coagulopathy (68%), alcohol abuse (21%), peripheral vascular disease (22%), myocardial infarction (17%), deep vein thrombosis (119%), sepsis (105%), pneumonia (171%), stroke (164%), urinary tract infection (112%), blood loss (95%), cardiac catheterization (86%), percutaneous transluminal coronary angioplasty (24%), and blood transfusion (206%). The percentage of UA patients with ≥2 days of hospital stay has decreased from 15% to 3.7%, whereas the average costs of managing a UA patient in the hospital have increased by 175%.
CONCLUSIONS: More than half of patients admitted with UA stay in the hospital for ≥2 days, with the most important determinants being pre-existing medical comorbidities and inpatient complications.

Entities:  

Keywords:  Unstable angina; acute coronary syndrome (ACS); length of stay

Year:  2018        PMID: 30603642      PMCID: PMC6312815          DOI: 10.21037/atm.2018.11.10

Source DB:  PubMed          Journal:  Ann Transl Med        ISSN: 2305-5839


  20 in total

1.  ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: executive summary and recommendations. A report of the American College of Cardiology/American Heart Association task force on practice guidelines (committee on the management of patients with unstable angina).

Authors:  E Braunwald; E M Antman; J W Beasley; R M Califf; M D Cheitlin; J S Hochman; R H Jones; D Kereiakes; J Kupersmith; T N Levin; C J Pepine; J W Schaeffer; E E Smith; D E Steward; P Theroux; R J Gibbons; J S Alpert; K A Eagle; D P Faxon; V Fuster; T J Gardner; G Gregoratos; R O Russell; S C Smith
Journal:  Circulation       Date:  2000-09-05       Impact factor: 29.690

2.  Length of stay, admission types, psychiatric diagnoses, and the implications of stigma in African Americans in the nationwide inpatient sample.

Authors:  Lois Bolden; Mona Newsome Wicks
Journal:  Issues Ment Health Nurs       Date:  2005-12       Impact factor: 1.835

3.  Ability of minor elevations of troponins I and T to predict benefit from an early invasive strategy in patients with unstable angina and non-ST elevation myocardial infarction: results from a randomized trial.

Authors:  D A Morrow; C P Cannon; N Rifai; M J Frey; R Vicari; N Lakkis; D H Robertson; D A Hille; P T DeLucca; P M DiBattiste; L A Demopoulos; W S Weintraub; E Braunwald
Journal:  JAMA       Date:  2001-11-21       Impact factor: 56.272

4.  Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein IIb/IIIa inhibitor tirofiban.

Authors:  C P Cannon; W S Weintraub; L A Demopoulos; R Vicari; M J Frey; N Lakkis; F J Neumann; D H Robertson; P T DeLucca; P M DiBattiste; C M Gibson; E Braunwald
Journal:  N Engl J Med       Date:  2001-06-21       Impact factor: 91.245

5.  Value of first day angiography/angioplasty in evolving Non-ST segment elevation myocardial infarction: an open multicenter randomized trial. The VINO Study.

Authors:  R Spacek; P Widimský; Z Straka; E Jiresová; J Dvorák; R Polásek; I Karel; R Jirmár; L Lisa; T Budesínský; F Málek; P Stanka
Journal:  Eur Heart J       Date:  2002-02       Impact factor: 29.983

6.  Effect on survival of acute myocardial infarction in Killip classes II or III patients undergoing invasive coronary procedures.

Authors:  D Rott; S Behar; J Leor; H Hod; V Boyko; L Mandelzweig; S Gottlieb
Journal:  Am J Cardiol       Date:  2001-09-15       Impact factor: 2.778

7.  Early invasive versus selectively invasive management for acute coronary syndromes.

Authors:  Robbert J de Winter; Fons Windhausen; Jan Hein Cornel; Peter H J M Dunselman; Charles L Janus; Peter E F Bendermacher; H Rolf Michels; Gerard T Sanders; Jan G P Tijssen; Freek W A Verheugt
Journal:  N Engl J Med       Date:  2005-09-15       Impact factor: 91.245

8.  Invasive compared with non-invasive treatment in unstable coronary-artery disease: FRISC II prospective randomised multicentre study. FRagmin and Fast Revascularisation during InStability in Coronary artery disease Investigators.

Authors: 
Journal:  Lancet       Date:  1999-08-28       Impact factor: 79.321

9.  Interventional versus conservative treatment for patients with unstable angina or non-ST-elevation myocardial infarction: the British Heart Foundation RITA 3 randomised trial. Randomized Intervention Trial of unstable Angina.

Authors:  K A A Fox; P A Poole-Wilson; R A Henderson; T C Clayton; D A Chamberlain; T R D Shaw; D J Wheatley; S J Pocock
Journal:  Lancet       Date:  2002-09-07       Impact factor: 79.321

10.  Determinants of costs and the length of stay in acute coronary syndromes: a real life analysis of more than 10,000 patients.

Authors:  Matthias Bramkamp; Dragana Radovanovic; Paul Erne; Thomas D Szucs
Journal:  Cardiovasc Drugs Ther       Date:  2007-10       Impact factor: 3.727

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  1 in total

1.  Efficacy of Shexiang Baoxin Pills for the treatment of unstable angina pectoris: Protocol of systemic review and meta-analysis.

Authors:  Huadong Chen; Qianqian Dong; Xiang Zheng
Journal:  Medicine (Baltimore)       Date:  2019-09       Impact factor: 1.817

  1 in total

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