Ieva Zukaite1,2, Kaveeta K Bedi1, Shahnaz Ali3, Mayank A Nanavaty4,5. 1. Sussex Eye Hospital, Brighton & Sussex University Hospitals NHS Trust, Eastern Road, Brighton, BN2 5BF, UK. 2. Medical Faculty, Otto-von-Guericke-University Magdeburg, 39120, Magdeburg, Germany. 3. Brighton & Sussex Medical School, University of Sussex, Falmer, Brighton, BN1 9PX, UK. 4. Sussex Eye Hospital, Brighton & Sussex University Hospitals NHS Trust, Eastern Road, Brighton, BN2 5BF, UK. mayank.nanavaty@bsuh.nhs.uk. 5. Brighton & Sussex Medical School, University of Sussex, Falmer, Brighton, BN1 9PX, UK. mayank.nanavaty@bsuh.nhs.uk.
Abstract
PURPOSE: To assess the effect of peripheral corneal relaxing incisions (PCRI) for astigmatism between 0.75 and 2.5 dioptres during cataract surgery on corneal densitometry (CD). METHODS: In this prospective, randomised study, 80 eyes (80 patients), received either tIOL or PCRI. Assessment at pre-operative and 1, 3, 6, 12 months post-operative visit included uncorrected (UCDVA) and best-corrected distance visual acuity (BCDVA), spherical equivalent (SEQ) (only post-operatively), mean anterior and posterior keratometric astigmatism (KA) and CD with Schiempflug system. CD was analysed in four concentric radial zones from centre to periphery (Zone 1 to 4) and in 3 layers (anterior, mid-stromal and posterior). RESULTS: Comparing tIOLs vs. PCRIs, there was no significant difference in the UCDVA, BCDVA and SEQ. In PCRI group, anterior KA decreased at 1 month and remained stable thereafter. For zones 1, 2 and 3, CD significantly reduced after 3 months with tIOLs whereas with PCRIs, it reduced 1 month onwards. For zone 4, CD reduced only at 12 months with tIOLs compared to 3 months onwards with PCRIs. In both groups CD was higher in the zone 4 and anterior layer. Significant reduction in CD was found in all three layers of cornea after 3 months in tIOL and after first month in PCRI groups, respectively. CONCLUSIONS:Cataract surgery alone reduces the CD. Reducing keratometric astigmatism with PCRIs shows significant differences in CD from early post-operative period for central and anterior corneal layer.
RCT Entities:
PURPOSE: To assess the effect of peripheral corneal relaxing incisions (PCRI) for astigmatism between 0.75 and 2.5 dioptres during cataract surgery on corneal densitometry (CD). METHODS: In this prospective, randomised study, 80 eyes (80 patients), received either tIOL or PCRI. Assessment at pre-operative and 1, 3, 6, 12 months post-operative visit included uncorrected (UCDVA) and best-corrected distance visual acuity (BCDVA), spherical equivalent (SEQ) (only post-operatively), mean anterior and posterior keratometric astigmatism (KA) and CD with Schiempflug system. CD was analysed in four concentric radial zones from centre to periphery (Zone 1 to 4) and in 3 layers (anterior, mid-stromal and posterior). RESULTS: Comparing tIOLs vs. PCRIs, there was no significant difference in the UCDVA, BCDVA and SEQ. In PCRI group, anterior KA decreased at 1 month and remained stable thereafter. For zones 1, 2 and 3, CD significantly reduced after 3 months with tIOLs whereas with PCRIs, it reduced 1 month onwards. For zone 4, CD reduced only at 12 months with tIOLs compared to 3 months onwards with PCRIs. In both groups CD was higher in the zone 4 and anterior layer. Significant reduction in CD was found in all three layers of cornea after 3 months in tIOL and after first month in PCRI groups, respectively. CONCLUSIONS:Cataract surgery alone reduces the CD. Reducing keratometric astigmatism with PCRIs shows significant differences in CD from early post-operative period for central and anterior corneal layer.
Authors: F Poyales; N Garzón; J Mendicute; I Illarramendi; P Caro; O Jáñez; F Argüeso; A López Journal: Eye (Lond) Date: 2017-06-16 Impact factor: 3.775
Authors: Nuria Garzón; Francisco Poyales; Igor Illarramendi; Javier Mendicute; Óscar Jáñez; Pedro Caro; Alfredo López; Francisco Argüeso Journal: Int Ophthalmol Date: 2016-11-11 Impact factor: 2.031
Authors: Jonathan C Lake; Gustavo Victor; Gerry Clare; Gustavo Jm Porfírio; Ashleigh Kernohan; Jennifer R Evans Journal: Cochrane Database Syst Rev Date: 2019-12-17