Literature DB >> 3060014

Biocatalysis made to order.

G Tripathi1.   

Abstract

Recombinant DNA technology is now being explored to engineer enzyme molecules. It has many far-reaching applications in biocatalytic processes of enzyme engineering. The facts have pursued certain important industrial, biomedical, and environmental problems. These current excitements are mainly focused on the basis of gene cloning and in vitro mutagenesis for overproduction and redesigning of enzymes, as well as their probable implications in industry, antibiotic research, and waste degradation.

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Year:  1988        PMID: 3060014     DOI: 10.1007/bf02921464

Source DB:  PubMed          Journal:  Appl Biochem Biotechnol        ISSN: 0273-2289            Impact factor:   2.926


  58 in total

1.  Aflatoxin B1 metabolism to aflatoxicol and derivatives lethal to Bacillus subtilis GSY 1057 by rainbow trout (Salmo gairdneri) liver.

Authors:  G L Schoenhard; D J Lee; S E Howell; N E Pawlowski; L M Libbey; R O Sinnhuber
Journal:  Cancer Res       Date:  1976-06       Impact factor: 12.701

Review 2.  Tinkering with enzymes: what are we learning?

Authors:  J R Knowles
Journal:  Science       Date:  1987-06-05       Impact factor: 47.728

3.  Five hundredfold overproduction of DNA ligase after induction of a hybrid lambda lysogen constructed in vitro.

Authors:  S M Panasenko; J R Cameron; R W Davis; I R Lehman
Journal:  Science       Date:  1977-04-08       Impact factor: 47.728

4.  Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors.

Authors:  M J Zoller; M Smith
Journal:  Methods Enzymol       Date:  1983       Impact factor: 1.600

5.  Isolation of a thermostable enzyme variant by cloning and selection in a thermophile.

Authors:  H Liao; T McKenzie; R Hageman
Journal:  Proc Natl Acad Sci U S A       Date:  1986-02       Impact factor: 11.205

6.  Metabolic activation and covalent binding of benzo[a]pyrene to deoxyribonucleic acid catalyzed by liver enzymes of marine fish.

Authors:  U Varanasi; D J Gmur
Journal:  Biochem Pharmacol       Date:  1980-03-01       Impact factor: 5.858

7.  Reduction of the toxicity and mutagenicity of alkylating agents in mammalian cells harboring the Escherichia coli alkyltransferase gene.

Authors:  J Brennand; G P Margison
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

8.  Effect of amino acid substitutions on the catalytic and regulatory properties of aspartate transcarbamoylase.

Authors:  E A Robey; S R Wente; D W Markby; A Flint; Y R Yang; H K Schachman
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

9.  Specific-purpose plasmid cloning vectors. I. Low copy number, temperature-sensitive, mobilization-defective pSC101-derived containment vectors.

Authors:  T Hashimoto-Gotoh; F C Franklin; A Nordheim; K N Timmis
Journal:  Gene       Date:  1981-12       Impact factor: 3.688

10.  Broad host range DNA cloning system for gram-negative bacteria: construction of a gene bank of Rhizobium meliloti.

Authors:  G Ditta; S Stanfield; D Corbin; D R Helinski
Journal:  Proc Natl Acad Sci U S A       Date:  1980-12       Impact factor: 11.205

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