Literature DB >> 3058669

Metabolites of microorganisms. 247. Phenazines from Streptomyces antibioticus, strain Tü 2706.

A Geiger1, W Keller-Schierlein, M Brandl, H Zähner.   

Abstract

From a strain of Streptomyces antibioticus seven yellow phenazines were isolated. The antibacterially most active antibiotic was identified as (-)-saphenamycin, a second one with compound DC-86-Y (saphenic acid). Three compounds were new: Saphenic acid methyl ether, 6-acetylphenazine-1-carboxylic acid and an inseparable mixture of fatty acid esters of saphenic acid. Two simple phenazines were phenazine-1-carboxylic acid (tubermycin B) and unsubstituted phenazine, which was isolated for the first time from a microorganism.

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Year:  1988        PMID： 3058669     DOI： 10.7164/antibiotics.41.1542

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  8 in total

1.  Diastaphenazine, a new dimeric phenazine from an endophytic Streptomyces diastaticus subsp. ardesiacus.

Authors:  Yiqing Li; Li Han; He Rong; Liya Li; Lixing Zhao; Longxia Wu; Lihua Xu; Yi Jiang; Xueshi Huang
Journal:  J Antibiot (Tokyo)       Date:  2014-09-17       Impact factor: 2.649

2.  Refactoring the Cryptic Streptophenazine Biosynthetic Gene Cluster Unites Phenazine, Polyketide, and Nonribosomal Peptide Biochemistry.

Authors:  Katherine D Bauman; Jie Li; Kazuya Murata; Simone M Mantovani; Samira Dahesh; Victor Nizet; Hanna Luhavaya; Bradley S Moore
Journal:  Cell Chem Biol       Date:  2019-03-07       Impact factor: 8.116

3.  Antifungal, Anticancer and Aminopeptidase Inhibitory Potential of a Phenazine Compound Produced by Lactococcus BSN307.

Authors:  Kontham Kulangara Varsha; Gopalan Nishant; Srambikal Mohandas Sneha; Ganesan Shilpa; Leena Devendra; Sulochana Priya; Kesavan Madhavan Nampoothiri
Journal:  Indian J Microbiol       Date:  2016-05-21       Impact factor: 2.461

4.  Ring-Closure Mechanisms Mediated by Laccase to Synthesize Phenothiazines, Phenoxazines, and Phenazines.

Authors:  Veronika Hahn; Annett Mikolasch; Josephine Weitemeyer; Sebastian Petters; Timo Davids; Michael Lalk; Jan-Wilm Lackmann; Frieder Schauer
Journal:  ACS Omega       Date:  2020-06-08

5.  Induction of Antibacterial Metabolites by Co-Cultivation of Two Red-Sea-Sponge-Associated Actinomycetes Micromonospora sp. UR56 and Actinokinespora sp. EG49.

Authors:  Mohamed S Hifnawy; Hossam M Hassan; Rabab Mohammed; Mohamed M Fouda; Ahmed M Sayed; Ahmed A Hamed; Sameh F AbouZid; Mostafa E Rateb; Hani A Alhadrami; Usama Ramadan Abdelmohsen
Journal:  Mar Drugs       Date:  2020-05-05       Impact factor: 5.118

6.  Phenazine Derivatives with Anti-Inflammatory Activity from the Deep-Sea Sediment-Derived Yeast-Like Fungus Cystobasidium laryngis IV17-028.

Authors:  Hwa-Sun Lee; Jong Soon Kang; Byeoung-Kyu Choi; Hyi-Seung Lee; Yeon-Ju Lee; Jihoon Lee; Hee Jae Shin
Journal:  Mar Drugs       Date:  2019-08-19       Impact factor: 5.118

7.  Genomic characterization of a new endophytic Streptomyces kebangsaanensis identifies biosynthetic pathway gene clusters for novel phenazine antibiotic production.

Authors:  Juwairiah Remali; Nurul 'Izzah Mohd Sarmin; Chyan Leong Ng; John J L Tiong; Wan M Aizat; Loke Kok Keong; Noraziah Mohamad Zin
Journal:  PeerJ       Date:  2017-11-29       Impact factor: 2.984

8.  A genetic screen in combination with biochemical analysis in Saccharomyces cerevisiae indicates that phenazine-1-carboxylic acid is harmful to vesicular trafficking and autophagy.

Authors:  Xiaolong Zhu; Yan Zeng; Xiu Zhao; Shenshen Zou; Ya-Wen He; Yongheng Liang
Journal:  Sci Rep       Date:  2017-05-16       Impact factor: 4.379
  8 in total

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