Alex Presciutti1, Evie Sobczak1, Jennifer A Sumner2, David J Roh1, Soojin Park1, Jan Claassen1, Ian Kronish2, Sachin Agarwal3. 1. Department of Neurology, Columbia University Medical Center, New York, NY, United States. 2. Center for Behavioral Cardiovascular Health, Columbia University Medical Center, New York, NY, United States. 3. Department of Neurology, Columbia University Medical Center, New York, NY, United States. Electronic address: sa2512@columbia.edu.
Abstract
PURPOSE: To determine the association of depressive and PTSD symptoms with cardiac arrest survivors' long-term recovery perceptions, after accounting for cognitive status, functional independence, and medical comorbidities. METHODS: Perceived recovery of 78 cardiac arrest survivors at 6-months post-hospital discharge was assessed through the question, "Do you feel that you have made a complete recovery from your arrest?" Psychological symptoms were measured using the Center for Epidemiological Studies-Depression scale (CES-D) and the PTSD Checklist-Specific (PCLS). Logistic regression was utilized to assess the association between psychological symptoms with positive and negative recovery perceptions, adjusting for demographics, cognitive impairment, functional dependence, and medical comorbidities. RESULTS: At 6 months, 53% of patients (n = 41) had negative recovery perceptions. 32.1% (n = 25) of patients screened for depression and 28.2% (n = 22) for PTSD. Patients with higher CES-D scores were significantly more likely to have negative recovery perceptions in both unadjusted and adjusted analyses (OR: 1.10, 95% CI [1.03, 1.16], p < .01). PCL-S scores were significantly associated with negative recovery perceptions in an unadjusted model (OR: 1.05, 95% CI [1.01, 1.10], p < .01), but not after adjustment of covariates. CONCLUSIONS: In contrast with cognitive and functional measures, depressive symptoms were strongly associated with cardiac arrest survivors' negative recovery perceptions at 6-months post-discharge.
PURPOSE: To determine the association of depressive and PTSD symptoms with cardiac arrest survivors' long-term recovery perceptions, after accounting for cognitive status, functional independence, and medical comorbidities. METHODS: Perceived recovery of 78 cardiac arrest survivors at 6-months post-hospital discharge was assessed through the question, "Do you feel that you have made a complete recovery from your arrest?" Psychological symptoms were measured using the Center for Epidemiological Studies-Depression scale (CES-D) and the PTSD Checklist-Specific (PCLS). Logistic regression was utilized to assess the association between psychological symptoms with positive and negative recovery perceptions, adjusting for demographics, cognitive impairment, functional dependence, and medical comorbidities. RESULTS: At 6 months, 53% of patients (n = 41) had negative recovery perceptions. 32.1% (n = 25) of patients screened for depression and 28.2% (n = 22) for PTSD. Patients with higher CES-D scores were significantly more likely to have negative recovery perceptions in both unadjusted and adjusted analyses (OR: 1.10, 95% CI [1.03, 1.16], p < .01). PCL-S scores were significantly associated with negative recovery perceptions in an unadjusted model (OR: 1.05, 95% CI [1.01, 1.10], p < .01), but not after adjustment of covariates. CONCLUSIONS: In contrast with cognitive and functional measures, depressive symptoms were strongly associated with cardiac arrest survivors' negative recovery perceptions at 6-months post-discharge.
Keywords:
Cardiac arrest; Cognitive dysfunction; Depression; Neuropsychological tests; Patient report outcome measures; Perception; Posttraumatic stress disorder; Value based health care
Authors: Karina W Davidson; Matthew M Burg; Ian M Kronish; Daichi Shimbo; Lucia Dettenborn; Roxana Mehran; David Vorchheimer; Lynn Clemow; Joseph E Schwartz; Francois Lespérance; Nina Rieckmann Journal: Arch Gen Psychiatry Date: 2010-05
Authors: E W Ely; R Margolin; J Francis; L May; B Truman; R Dittus; T Speroff; S Gautam; G R Bernard; S K Inouye Journal: Crit Care Med Date: 2001-07 Impact factor: 7.598
Authors: S A Mayer; K T Kreiter; D Copeland; G L Bernardini; J E Bates; S Peery; J Claassen; Y E Du; E S Connolly Journal: Neurology Date: 2002-12-10 Impact factor: 9.910
Authors: G Lilja; G Nilsson; N Nielsen; H Friberg; C Hassager; M Koopmans; M Kuiper; A Martini; J Mellinghoff; P Pelosi; M Wanscher; M P Wise; I Östman; T Cronberg Journal: Resuscitation Date: 2015-10-09 Impact factor: 5.262
Authors: Tim A Ahles; John H Wasson; Janette L Seville; Deborah J Johnson; Bernard F Cole; Brett Hanscom; Therese A Stukel; Elizabeth McKinstry Journal: Ann Fam Med Date: 2006 Jul-Aug Impact factor: 5.166
Authors: Véronique R M P Moulaert; Jeanine A Verbunt; Caroline M van Heugten; Derick T Wade Journal: Resuscitation Date: 2008-12-30 Impact factor: 5.262
Authors: Sachin Agarwal; Jeffrey L Birk; Sabine L Abukhadra; Danielle A Rojas; Talea M Cornelius; Maja Bergman; Bernard P Chang; Donald E Edmondson; Ian M Kronish Journal: Curr Cardiol Rep Date: 2022-08-03 Impact factor: 3.955
Authors: Alex Presciutti; Jonathan Shaffer; Jennifer A Sumner; Mitchell S V Elkind; David J Roh; Soojin Park; Jan Claassen; Donald Edmondson; Sachin Agarwal Journal: Ann Behav Med Date: 2020-05-25
Authors: Jerry P Nolan; Claudio Sandroni; Bernd W Böttiger; Alain Cariou; Tobias Cronberg; Hans Friberg; Cornelia Genbrugge; Kirstie Haywood; Gisela Lilja; Véronique R M Moulaert; Nikolaos Nikolaou; Theresa Mariero Olasveengen; Markus B Skrifvars; Fabio Taccone; Jasmeet Soar Journal: Intensive Care Med Date: 2021-03-25 Impact factor: 17.440
Authors: Alex Presciutti; Mary M Newman; Kelly N Sawyer; Sachin Agarwal; Sarah M Perman Journal: Ther Hypothermia Temp Manag Date: 2021-05-11 Impact factor: 1.369
Authors: Felipe Teran; Shaun K McGovern; Katie N Dainty; Kelly N Sawyer; Audrey L Blewer; Michael C Kurz; Joshua C Reynolds; Jon C Rittenberger; Marina Del Rios Rivera; Marion Leary Journal: J Am Heart Assoc Date: 2019-05-07 Impact factor: 5.501