Literature DB >> 30585579

Who Should Regulate Preimplantation Genetic Diagnosis in the United States?

Michelle Bayefsky.   

Abstract

Unlike in many European countries, preimplantation genetic diagnosis (PGD) is not regulated in the United States. As a result, PGD may be used for any condition for which genetic testing is available, at the discretion of fertility specialists and their patients. This essay explores the question of who should be responsible for regulating PGD in the United States. Federal or state regulation of PGD in the United States is likely to be challenging and problematic for several reasons, including the proximity of PGD to the abortion debate. I propose that PGD regulation in the United States can be most appropriately performed by health professionals using professional society guidelines that set standards for clinical practice.
© 2018 American Medical Association. All Rights Reserved.

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Year:  2018        PMID: 30585579     DOI: 10.1001/amajethics.2018.1160

Source DB:  PubMed          Journal:  AMA J Ethics


  9 in total

1.  Screening Human Embryos for Polygenic Traits Has Limited Utility.

Authors:  Ehud Karavani; Or Zuk; Danny Zeevi; Nir Barzilai; Nikos C Stefanis; Alex Hatzimanolis; Nikolaos Smyrnis; Dimitrios Avramopoulos; Leonid Kruglyak; Gil Atzmon; Max Lam; Todd Lencz; Shai Carmi
Journal:  Cell       Date:  2019-11-21       Impact factor: 41.582

2.  Preimplantation Genetic Testing for Genetic Kidney Disease: Addressing Moral Uncertainties and Access Inequity.

Authors:  Wylie Burke; Kathleen M West
Journal:  Clin J Am Soc Nephrol       Date:  2020-08-27       Impact factor: 8.237

3.  Polygenic risk scoring of human embryos: a qualitative study of media coverage.

Authors:  Tiny Pagnaer; Maria Siermann; Pascal Borry; Olga Tšuiko
Journal:  BMC Med Ethics       Date:  2021-09-18       Impact factor: 2.834

4.  Evaluating standards for 'serious' disease for preimplantation genetic testing: a multi-case study on regulatory frameworks in Japan, the UK, and Western Australia.

Authors:  Kate Nakasato; Beverley Anne Yamamoto; Kazuto Kato
Journal:  Hum Genomics       Date:  2022-05-18       Impact factor: 6.481

5.  Problems with Using Polygenic Scores to Select Embryos.

Authors:  Patrick Turley; Michelle N Meyer; Nancy Wang; David Cesarini; Evelynn Hammonds; Alicia R Martin; Benjamin M Neale; Heidi L Rehm; Louise Wilkins-Haug; Daniel J Benjamin; Steven Hyman; David Laibson; Peter M Visscher
Journal:  N Engl J Med       Date:  2021-07-01       Impact factor: 91.245

6.  ART with PGD: Risky heredity and stratified reproduction.

Authors:  Ilana Löwy
Journal:  Reprod Biomed Soc Online       Date:  2020-11-05

7.  Predictive Prenatal Diagnosis for Infantile-onset Inflammatory Bowel Disease Because of Interleukin-10 Signalling Defects.

Authors:  Ziqing Ye; Wenhui Hu; Bingbing Wu; Yueping Zhang; Caixia Lei; Isabelle Williams; Dror S Shouval; Hirokazu Kanegane; Kyung Mo Kim; Lissy de Ridder; Neil Shah; Galina Ling; Baruch Yerushalmi; Daniel Kotlarz; Scott Snapper; Ruth Horn; Christoph Klein; Aleixo M Muise; Ying Huang; Holm H Uhlig
Journal:  J Pediatr Gastroenterol Nutr       Date:  2021-02-01       Impact factor: 3.288

8.  Preimplantation Genetic Testing of Multiple Endocrine Neoplasia Type 2A.

Authors:  Anders Würgler Hansen; Laura Kirstine Sønderberg Roos; Kristine Løssl; Christian Godballe; Jes Sloth Mathiesen
Journal:  Front Endocrinol (Lausanne)       Date:  2020-10-14       Impact factor: 5.555

9.  Three models for the regulation of polygenic scores in reproduction.

Authors:  Sarah Munday; Julian Savulescu
Journal:  J Med Ethics       Date:  2021-01-18       Impact factor: 2.903

  9 in total

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