Literature DB >> 30574180

Rheumatologists' knowledge of contraception, teratogens, and pregnancy risks.

Megan Eb Clowse1, Amanda M Eudy1, Jessica Revels2, Gillian D Sanders3,4,5, Lisa Criscione-Schreiber1.   

Abstract

INTRODUCTION: Rheumatologists are essential partners in planning and managing pregnancies in women with lupus. Whether they know the essentials of contraceptive and medical treatment in pregnancy, however, is unknown.
METHOD: Anonymous in-lecture surveys were completed by 270 rheumatologists to assess knowledge of contraceptive effectiveness, emergency contraception, medication teratogenicity, and lupus pregnancy risk assessment.
RESULTS: Rheumatologists knew the high effectiveness of the intrauterine device, but over-estimated the effectiveness of injectable medroxyprogesterone and condoms. Almost all identified methotrexate as a teratogen, but only 69% identified cyclophosphamide and 37% mycophenolate. Most rheumatologists knew that lupus activity in pregnancy is the main predictor of pregnancy outcomes, but underestimated the risks of hypertension and race.
CONCLUSION: To improve lupus pregnancy planning and management, rheumatologists would benefit from improved knowledge about contraceptive effectiveness, teratogens, and the risks from non-lupus factors for pregnancy complications.

Entities:  

Keywords:  Rheumatology; contraception; high-risk pregnancy; medical education

Year:  2018        PMID: 30574180      PMCID: PMC6295764          DOI: 10.1177/1753495X18771266

Source DB:  PubMed          Journal:  Obstet Med        ISSN: 1753-495X


  10 in total

1.  Leflunomide - A human teratogen? A still not answered question. An evaluation of the German Embryotox pharmacovigilance database.

Authors:  Corinna Weber-Schoendorfer; Evelin Beck; Tatjana Tissen-Diabaté; Christof Schaefer
Journal:  Reprod Toxicol       Date:  2017-05-03       Impact factor: 3.143

2.  Pregnancy outcomes in solid organ transplant recipients with exposure to mycophenolate mofetil or sirolimus.

Authors:  Nicole M Sifontis; Lisa A Coscia; Serban Constantinescu; Antonella F Lavelanet; Michael J Moritz; Vincent T Armenti
Journal:  Transplantation       Date:  2006-12-27       Impact factor: 4.939

3.  Pregnancy complicating systemic lupus erythematosus: a series of 86 cases.

Authors:  Qiang Wei; Yunwei Ouyang; Weiyue Zeng; Lijun Duan; Junli Ge; Hua Liao
Journal:  Arch Gynecol Obstet       Date:  2010-12-07       Impact factor: 2.344

4.  Predictors of Pregnancy Outcomes in Patients With Lupus: A Cohort Study.

Authors:  Jill P Buyon; Mimi Y Kim; Marta M Guerra; Carl A Laskin; Michelle Petri; Michael D Lockshin; Lisa Sammaritano; D Ware Branch; T Flint Porter; Allen Sawitzke; Joan T Merrill; Mary D Stephenson; Elisabeth Cohn; Lamya Garabet; Jane E Salmon
Journal:  Ann Intern Med       Date:  2015-08-04       Impact factor: 25.391

5.  Birth outcomes in women who have taken leflunomide during pregnancy.

Authors:  Christina D Chambers; Diana L Johnson; Luther K Robinson; Stephen R Braddock; Ronghui Xu; Janina Lopez-Jimenez; Nicole Mirrasoul; Elizabeth Salas; Yunjun J Luo; Shelia Jin; Kenneth Lyons Jones
Journal:  Arthritis Rheum       Date:  2010-05

6.  The impact of increased lupus activity on obstetric outcomes.

Authors:  Megan E B Clowse; Laurence S Magder; Frank Witter; Michelle Petri
Journal:  Arthritis Rheum       Date:  2005-02

7.  Receipt of prescription contraception by commercially insured women with chronic medical conditions.

Authors:  Anna E DeNoble; Kelli S Hall; Xiao Xu; Melissa K Zochowski; Kenneth Piehl; Vanessa K Dalton
Journal:  Obstet Gynecol       Date:  2014-06       Impact factor: 7.661

8.  U.S. Medical Eligibility Criteria for Contraceptive Use, 2016.

Authors:  Kathryn M Curtis; Naomi K Tepper; Tara C Jatlaoui; Erin Berry-Bibee; Leah G Horton; Lauren B Zapata; Katharine B Simmons; H Pamela Pagano; Denise J Jamieson; Maura K Whiteman
Journal:  MMWR Recomm Rep       Date:  2016-07-29

9.  Pregnancy outcome after methotrexate treatment for rheumatic disease prior to or during early pregnancy: a prospective multicenter cohort study.

Authors:  Corinna Weber-Schoendorfer; Christina Chambers; Evelin Wacker; Delphine Beghin; Nathalie Bernard; Svetlana Shechtman; Diana Johnson; Benedikte Cuppers-Maarschalkerweerd; Alessandra Pistelli; Maurizio Clementi; Ursula Winterfeld; Georgios Eleftheriou; Anna Pupco; Kelly Kao; Heli Malm; Elisabeth Elefant; Gideon Koren; Thierry Vial; Asher Ornoy; Reinhard Meister; Christof Schaefer
Journal:  Arthritis Rheumatol       Date:  2014-05       Impact factor: 10.995

10.  EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome.

Authors:  L Andreoli; G K Bertsias; N Agmon-Levin; S Brown; R Cervera; N Costedoat-Chalumeau; A Doria; R Fischer-Betz; F Forger; M F Moraes-Fontes; M Khamashta; J King; A Lojacono; F Marchiori; P L Meroni; M Mosca; M Motta; M Ostensen; C Pamfil; L Raio; M Schneider; E Svenungsson; M Tektonidou; S Yavuz; D Boumpas; A Tincani
Journal:  Ann Rheum Dis       Date:  2016-07-25       Impact factor: 19.103

  10 in total
  6 in total

1.  Provider perceptions on the management of lupus during pregnancy: barriers to improved care.

Authors:  M E B Clowse; A M Eudy; J Revels; L Neil; G D Sanders
Journal:  Lupus       Date:  2018-12-06       Impact factor: 2.911

2.  Perspectives of Adult Rheumatologists Regarding Family Planning Counseling and Care: A Qualitative Study.

Authors:  Mehret Birru Talabi; Megan E B Clowse; Susan J Blalock; Megan Hamm; Sonya Borrero
Journal:  Arthritis Care Res (Hoboken)       Date:  2020-03       Impact factor: 4.794

3.  The importance of pregnancy planning in lupus pregnancies.

Authors:  Aardra Rajendran; Amanda M Eudy; Stephen J Balevic; Megan E B Clowse
Journal:  Lupus       Date:  2021-01-28       Impact factor: 2.911

4.  Learning to listen: how empathetic engagement with patients can help overcome reproductive injustice.

Authors:  Megan E B Clowse
Journal:  Lupus Sci Med       Date:  2020-11

5.  Improving Knowledge of Lactation Compatibility of Antirheumatic Medications Among Providers Who Care for Patients With Rheumatic Disease.

Authors:  Brooke S Mills; Bonnie L Bermas
Journal:  ACR Open Rheumatol       Date:  2021-01-04

6.  Pregnancy Intention Screening in Patients With Systemic Rheumatic Diseases: Pilot Testing a Standardized Assessment Tool.

Authors:  Katherine P Pryor; Bill Albert; Sonali Desai; Susan Y Ritter; Laura Tarter; Jonathan Coblyn; Bonnie L Bermas; Leah M Santacroce; Caryn Dutton; Kari P Braaten; Lydia E Pace; Kathryn Rexrode; Elizabeth Janiak; Candace H Feldman
Journal:  ACR Open Rheumatol       Date:  2022-05-31
  6 in total

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