Literature DB >> 3056926

Two cellular components, PrlA and SecB, that recognize different sequence determinants are required for efficient protein export.

N J Trun1, J Stader, A Lupas, C Kumamoto, T J Silhavy.   

Abstract

We exploited the conditional-lethal phenotype of secB null mutations to demonstrate that SecB function was required for PrlA-mediated suppression of signal sequence mutations. The results of these experiments provide information about the functions performed and the sequence determinants recognized by each of these components of the protein export machinery of Escherichia coli.

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Year:  1988        PMID: 3056926      PMCID: PMC211706          DOI: 10.1128/jb.170.12.5928-5930.1988

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  6 in total

1.  Biochemical evidence for the secY24 defect in Escherichia coli protein translocation and its suppression by soluble cytoplasmic factors.

Authors:  J P Fandl; P C Tai
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

2.  A signal sequence receptor in the endoplasmic reticulum membrane.

Authors:  M Wiedmann; T V Kurzchalia; E Hartmann; T A Rapoport
Journal:  Nature       Date:  1987 Aug 27-Sep 2       Impact factor: 49.962

3.  Evidence for specificity at an early step in protein export in Escherichia coli.

Authors:  C A Kumamoto; J Beckwith
Journal:  J Bacteriol       Date:  1985-07       Impact factor: 3.490

4.  The antifolding activity of SecB promotes the export of the E. coli maltose-binding protein.

Authors:  D N Collier; V A Bankaitis; J B Weiss; P J Bassford
Journal:  Cell       Date:  1988-04-22       Impact factor: 41.582

5.  The spc ribosomal protein operon of Escherichia coli: sequence and cotranscription of the ribosomal protein genes and a protein export gene.

Authors:  D P Cerretti; D Dean; G R Davis; D M Bedwell; M Nomura
Journal:  Nucleic Acids Res       Date:  1983-05-11       Impact factor: 16.971

6.  Suppressor mutations that restore export of a protein with a defective signal sequence.

Authors:  S D Emr; S Hanley-Way; T J Silhavy
Journal:  Cell       Date:  1981-01       Impact factor: 41.582

  6 in total
  15 in total

1.  Escherichia coli SecB protein associates with exported protein precursors in vivo.

Authors:  C A Kumamoto
Journal:  Proc Natl Acad Sci U S A       Date:  1989-07       Impact factor: 11.205

2.  Modeling the effects of prl mutations on the Escherichia coli SecY complex.

Authors:  Margaret A Smith; William M Clemons; Cathrine J DeMars; Ann M Flower
Journal:  J Bacteriol       Date:  2005-09       Impact factor: 3.490

3.  Involvement of SecB, a chaperone, in the export of ribose-binding protein.

Authors:  J Kim; Y Lee; C Kim; C Park
Journal:  J Bacteriol       Date:  1992-08       Impact factor: 3.490

4.  Escherichia coli SecB stimulates export without maintaining export competence of ribose-binding protein signal sequence mutants.

Authors:  O Francetic; C A Kumamoto
Journal:  J Bacteriol       Date:  1996-10       Impact factor: 3.490

Review 5.  Insertion of proteins into bacterial membranes: mechanism, characteristics, and comparisons with the eucaryotic process.

Authors:  M H Saier; P K Werner; M Müller
Journal:  Microbiol Rev       Date:  1989-09

6.  A mutation of Escherichia coli SecA protein that partially compensates for the absence of SecB.

Authors:  L McFarland; O Francetić; C A Kumamoto
Journal:  J Bacteriol       Date:  1993-04       Impact factor: 3.490

7.  prlA suppression of defective export of maltose-binding protein in secB mutants of Escherichia coli.

Authors:  O Francetić; M P Hanson; C A Kumamoto
Journal:  J Bacteriol       Date:  1993-07       Impact factor: 3.490

Review 8.  The complete general secretory pathway in gram-negative bacteria.

Authors:  A P Pugsley
Journal:  Microbiol Rev       Date:  1993-03

Review 9.  SecB protein: a cytosolic export factor that associates with nascent exported proteins.

Authors:  C A Kumamoto
Journal:  J Bioenerg Biomembr       Date:  1990-06       Impact factor: 2.945

10.  A new suppressor of a lamB signal sequence mutation, prlZ1, maps to 69 minutes on the Escherichia coli chromosome.

Authors:  S Q Wei; J Stader
Journal:  J Bacteriol       Date:  1994-09       Impact factor: 3.490

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