| Literature DB >> 30554116 |
Asghar Fallah1, Ali Sadeghinia2, Houman Kahroba3, Amin Samadi4, Hamid Reza Heidari5, Behzad Bradaran6, Sirous Zeinali7, Ommoleila Molavi8.
Abstract
Angiogenesis is a critical step in the progression of almost all human malignancies and some other life-threatening diseases. Anti-angiogenic therapy is a novel and effective approach for treatment of angiogenesis-dependent diseases such as cancer, diabetic retinopathy, and age-related macular degeneration. In this article, we will review the main strategies developed for anti-angiogenic therapies beside their clinical applications, the major challenges, and the latest advances in the development of anti-angiogenesis-based targeted therapies.Entities:
Keywords: Angiogenesis-dependent diseases; Anti-angiogenesis; Anti-angiogenic therapeutics; Cancer; VEGF–VEGFR system receptors
Mesh:
Substances:
Year: 2018 PMID: 30554116 DOI: 10.1016/j.biopha.2018.12.022
Source DB: PubMed Journal: Biomed Pharmacother ISSN: 0753-3322 Impact factor: 6.529