Literature DB >> 33568517

Cell type-specific microRNA therapies for myocardial infarction.

Bohao Liu1,2, Bryan Wang1,2, Xiaokan Zhang1, Roberta Lock2, Trevor Nash1,2, Gordana Vunjak-Novakovic3,2.   

Abstract

Current interventions fail to recover injured myocardium after infarction and prompt the need for development of cardioprotective strategies. Of increasing interest is the therapeutic use of microRNAs to control gene expression through specific targeting of mRNAs. In this Review, we discuss current microRNA-based therapeutic strategies, describing the outcomes and limitations of key microRNAs with a focus on target cell types and molecular pathways. Last, we offer a perspective on the outlook of microRNA therapies for myocardial infarction, highlighting the outstanding challenges and emerging strategies.
Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

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Year:  2021        PMID： 33568517      PMCID： PMC8848299          DOI： 10.1126/scitranslmed.abd0914

Source DB:  PubMed          Journal:  Sci Transl Med        ISSN： 1946-6234            Impact factor:   17.956


  292 in total

1.  APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p.

Authors:  Kun Wang; Cui-Yun Liu; Lu-Yu Zhou; Jian-Xun Wang; Man Wang; Bing Zhao; Wen-Ke Zhao; Shi-Jun Xu; Li-Hua Fan; Xiao-Jie Zhang; Chang Feng; Chao-Qun Wang; Yan-Fang Zhao; Pei-Feng Li
Journal:  Nat Commun       Date:  2015-04-10       Impact factor: 14.919

2.  Taking heart--cardiac transplantation past, present, and future.

Authors:  Sharon A Hunt
Journal:  N Engl J Med       Date:  2006-07-20       Impact factor: 91.245

3.  Long Non-Coding RNA H19 Protects H9c2 Cells against Hypoxia-Induced Injury by Targeting MicroRNA-139.

Authors:  Li-Cheng Gong; Hai-Ming Xu; Gong-Liang Guo; Tao Zhang; Jing-Wei Shi; Chang Chang
Journal:  Cell Physiol Biochem       Date:  2017-11-24

4.  MicroRNA-19a attenuates hypoxia-induced cardiomyocyte apoptosis by downregulating NHE-1 expression and decreasing calcium overload.

Authors:  Jiaqi Ma; Zhangwei Chen; Yuanji Ma; Yan Xia; Kai Hu; You Zhou; Ao Chen; Juying Qian; Junbo Ge
Journal:  J Cell Biochem       Date:  2019-10-21       Impact factor: 4.429

5.  MicroRNA-141 regulates the expression level of ICAM-1 on endothelium to decrease myocardial ischemia-reperfusion injury.

Authors:  Rong Rong Liu; Jun Li; Jiu Yu Gong; Fang Kuang; Jia Yun Liu; Yu Si Zhang; Qian Li Ma; Chao Jun Song; Agnieszka D Truax; Feng Gao; Kun Yang; Bo Quan Jin; Li Hua Chen
Journal:  Am J Physiol Heart Circ Physiol       Date:  2015-09-14       Impact factor: 4.733

6.  MicroRNA-143-3p promotes human cardiac fibrosis via targeting sprouty3 after myocardial infarction.

Authors:  Cong Li; Jing Li; Ke Xue; Jun Zhang; Cong Wang; Qingqing Zhang; Xianlu Chen; Chuanzhou Gao; Xiao Yu; Lei Sun
Journal:  J Mol Cell Cardiol       Date:  2019-03-14       Impact factor: 5.000

7.  MicroRNA-150 targets ELK1 and modulates the apoptosis induced by ox-LDL in endothelial cells.

Authors:  Bing Qin; Yaqing Shu; Li Xiao; Tingting Lu; Yinyao Lin; Huan Yang; Zhengqi Lu
Journal:  Mol Cell Biochem       Date:  2017-01-21       Impact factor: 3.396

8.  Epicardial FSTL1 reconstitution regenerates the adult mammalian heart.

Authors:  Ke Wei; Vahid Serpooshan; Cecilia Hurtado; Marta Diez-Cuñado; Mingming Zhao; Sonomi Maruyama; Wenhong Zhu; Giovanni Fajardo; Michela Noseda; Kazuto Nakamura; Xueying Tian; Qiaozhen Liu; Andrew Wang; Yuka Matsuura; Paul Bushway; Wenqing Cai; Alex Savchenko; Morteza Mahmoudi; Michael D Schneider; Maurice J B van den Hoff; Manish J Butte; Phillip C Yang; Kenneth Walsh; Bin Zhou; Daniel Bernstein; Mark Mercola; Pilar Ruiz-Lozano
Journal:  Nature       Date:  2015-09-16       Impact factor: 49.962

9.  Cardiomyocyte-derived exosomal microRNA-92a mediates post-ischemic myofibroblast activation both in vitro and ex vivo.

Authors:  Xujun Wang; Marco Bruno Morelli; Alessandro Matarese; Celestino Sardu; Gaetano Santulli
Journal:  ESC Heart Fail       Date:  2020-01-25

10.  Mammalian heart renewal by pre-existing cardiomyocytes.

Authors:  Samuel E Senyo; Matthew L Steinhauser; Christie L Pizzimenti; Vicky K Yang; Lei Cai; Mei Wang; Ting-Di Wu; Jean-Luc Guerquin-Kern; Claude P Lechene; Richard T Lee
Journal:  Nature       Date:  2012-12-05       Impact factor: 49.962
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  4 in total

Review 1.  Nanocarrier-Based Targeted Therapies for Myocardial Infarction.

Authors:  Thomashire A George; Chuan-Chih Hsu; Annette Meeson; David J Lundy
Journal:  Pharmaceutics       Date:  2022-04-25       Impact factor: 6.525

Review 2.  MicroRNAs in Acute ST Elevation Myocardial Infarction-A New Tool for Diagnosis and Prognosis: Therapeutic Implications.

Authors:  Alina Ioana Scărlătescu; Miruna Mihaela Micheu; Nicoleta-Monica Popa-Fotea; Maria Dorobanțu
Journal:  Int J Mol Sci       Date:  2021-04-30       Impact factor: 5.923

Review 3.  Harnessing organs-on-a-chip to model tissue regeneration.

Authors:  Daniel Naveed Tavakol; Sharon Fleischer; Gordana Vunjak-Novakovic
Journal:  Cell Stem Cell       Date:  2021-06-03       Impact factor: 25.269

Review 4.  Role of miRNA-1 and miRNA-21 in Acute Myocardial Ischemia-Reperfusion Injury and Their Potential as Therapeutic Strategy.

Authors:  Eranthi Jayawardena; Lejla Medzikovic; Gregoire Ruffenach; Mansoureh Eghbali
Journal:  Int J Mol Sci       Date:  2022-01-28       Impact factor: 6.208
  4 in total

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