| Literature DB >> 30529326 |
Shuo Zhang1, Jian Zhang1, Ping Gao1, Lin Sun1, Yuning Song2, Dongwei Kang3, Xinyong Liu4, Peng Zhan5.
Abstract
In this review, we provide an overview of recent applications of crystallographic overlay-based molecular structure hybridization of lead compounds as a rational strategy for efficient drug discovery, with selected examples, and briefly discuss its advantages compared with other ligand-based methodologies.Mesh：
Year: 2018 PMID： 30529326 DOI： 10.1016/j.drudis.2018.11.021
Source DB: PubMed Journal: Drug Discov Today ISSN： 1359-6446 Impact factor: 7.851