Hsin-Yun Liu1, Wen-Che Tsai2, Ming-Jang Chiu3,4,5,6,7, Li-Yu Tang8, Huey-Jane Lee8, Yea-Ing L Shyu9,10,11,12, Woan-Shyuan Wang9. 1. 1 Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan. 2. 2 Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan. 3. 3 Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan. 4. 4 Graduate Institute of Brain and Mind Sciences, National Taiwan University, Taipei, Taiwan. 5. 5 Graduate Institute of Psychology, National Taiwan University, Taipei, Taiwan. 6. 6 Graduate Institute of Biomedical Engineering and Bioinformatics, National Taiwan University, Taipei, Taiwan. 7. 7 College of Medicine, National Taiwan University, Taipei, Taiwan. 8. 8 Taiwan Alzheimer's Disease Association, Taipei, Taiwan. 9. 9 School of Nursing, College of Medicine, Chang Gung University, Taoyuan, Taiwan. 10. 10 Department of Orthopedic Surgery, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan. 11. 11 Department of Nursing, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan. 12. 12 Department of Gerontology and Health Care Management, Chang Gung University of Science and Technology, Taoyuan, Taiwan.
Abstract
BACKGROUND: To examine the relationships between cognitive dysfunction status and quality of life. METHODS: Secondary analysis of a nationwide population-based survey (≥65 years) in Taiwan. The 5-dimension EuroQoL questionnaire (EQ-5D) was completed by 10 013 participants. RESULTS: Participants with mild cognitive impairment (MCI; odds ratio = 4.88), very mild dementia (VMD; 7.96), or dementia (32.85) were more likely than those with normal cognition to report self-care problems. Participants with MCI (3.86), VMD (9.26), or dementia (31.61) were more likely to have usual-activity problems, and those with MCI (3.04), VMD (3.82), or dementia (9.23) were more likely to have mobility problems. Participants with MCI (2.10 and 2.14), VMD (2.77 and 2.18), or dementia (3.04 and 3.02) were more likely to report pain/discomfort and anxiety/depression. CONCLUSION: Dementia was negatively associated with EQ-5D, especially self-care, usual activities, and mobility. Mild cognitive impairment or VMD was also negatively associated, with VMD more negatively associated. Developing interventions for patients with specific cognitive dysfunctions is critical.
BACKGROUND: To examine the relationships between cognitive dysfunction status and quality of life. METHODS: Secondary analysis of a nationwide population-based survey (≥65 years) in Taiwan. The 5-dimension EuroQoL questionnaire (EQ-5D) was completed by 10 013 participants. RESULTS:Participants with mild cognitive impairment (MCI; odds ratio = 4.88), very mild dementia (VMD; 7.96), or dementia (32.85) were more likely than those with normal cognition to report self-care problems. Participants with MCI (3.86), VMD (9.26), or dementia (31.61) were more likely to have usual-activity problems, and those with MCI (3.04), VMD (3.82), or dementia (9.23) were more likely to have mobility problems. Participants with MCI (2.10 and 2.14), VMD (2.77 and 2.18), or dementia (3.04 and 3.02) were more likely to report pain/discomfort and anxiety/depression. CONCLUSION:Dementia was negatively associated with EQ-5D, especially self-care, usual activities, and mobility. Mild cognitive impairment or VMD was also negatively associated, with VMD more negatively associated. Developing interventions for patients with specific cognitive dysfunctions is critical.
Entities:
Keywords:
cognitive dysfunction; dementia; health-related quality of life; mild cognitive impairment; very mild dementia
Authors: Violeta Clement-Carbonell; Rosario Ferrer-Cascales; Nicolás Ruiz-Robledillo; María Rubio-Aparicio; Irene Portilla-Tamarit; María José Cabañero-Martínez Journal: Int J Environ Res Public Health Date: 2019-06-30 Impact factor: 3.390
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