Literature DB >> 30517891

Peeking under the Hood of Naive T Cells.

Wei Xu1, Jonathan D Powell2.   

Abstract

Signaling and transcriptional regulation of metabolic reprogramming upon T cell activation has been studied intensively. In this issue of Cell Metabolism, Ricciardi et al. (2018) show that translational regulation of key metabolic enzymes GLUT1 and ACC1 plays a novel role in human naive CD4 T cell activation and subset differentiation.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Year:  2018        PMID： 30517891      PMCID： PMC8291339          DOI： 10.1016/j.cmet.2018.11.008

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  11 in total

1.  The liver kinase B1 is a central regulator of T cell development, activation, and metabolism.

Authors:  Nancie J MacIver; Julianna Blagih; Donte C Saucillo; Luciana Tonelli; Takla Griss; Jeffrey C Rathmell; Russell G Jones
Journal:  J Immunol       Date:  2011-09-19       Impact factor: 5.422

2.  The CD28 signaling pathway regulates glucose metabolism.

Authors:  Kenneth A Frauwirth; James L Riley; Marian H Harris; Richard V Parry; Jeffrey C Rathmell; David R Plas; Rebecca L Elstrom; Carl H June; Craig B Thompson
Journal:  Immunity       Date:  2002-06       Impact factor: 31.745

Review 3.  The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism.

Authors:  Jonathan D Powell; Greg M Delgoffe
Journal:  Immunity       Date:  2010-09-24       Impact factor: 31.745

4.  The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment.

Authors:  Greg M Delgoffe; Thomas P Kole; Yan Zheng; Paul E Zarek; Krystal L Matthews; Bo Xiao; Paul F Worley; Sara C Kozma; Jonathan D Powell
Journal:  Immunity       Date:  2009-06-19       Impact factor: 31.745

Review 5.  Fueling immunity: insights into metabolism and lymphocyte function.

Authors:  Erika L Pearce; Maya C Poffenberger; Chih-Hao Chang; Russell G Jones
Journal:  Science       Date:  2013-10-11       Impact factor: 47.728

Review 6.  Metabolic regulation of T lymphocytes.

Authors:  Nancie J MacIver; Ryan D Michalek; Jeffrey C Rathmell
Journal:  Annu Rev Immunol       Date:  2013-01-03       Impact factor: 28.527

7.  T cell Myc-tabolism.

Authors:  Jeffrey C Rathmell
Journal:  Immunity       Date:  2011-12-23       Impact factor: 31.745

8.  Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways.

Authors:  Sarah R Jacobs; Catherine E Herman; Nancie J Maciver; Jessica A Wofford; Heather L Wieman; Jeremy J Hammen; Jeffrey C Rathmell
Journal:  J Immunol       Date:  2008-04-01       Impact factor: 5.422

Review 9.  Malonyl-CoA, a key signaling molecule in mammalian cells.

Authors:  David Saggerson
Journal:  Annu Rev Nutr       Date:  2008       Impact factor: 11.848

10.  The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling.

Authors:  Sara Ricciardi; Nicola Manfrini; Roberta Alfieri; Piera Calamita; Maria Cristina Crosti; Simone Gallo; Rolf Müller; Massimiliano Pagani; Sergio Abrignani; Stefano Biffo
Journal:  Cell Metab       Date:  2018-09-06       Impact factor: 27.287
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