Literature DB >> 22195738

T cell Myc-tabolism.

Jeffrey C Rathmell1.   

Abstract

T cell activation leads to a dramatic demand for energy and biosynthetic precursors that is met by increased glucose and glutamine metabolism. In this issue of Immunity, Wang et al. (2011) show that Myc is essential in T cell metabolic reprogramming.
Copyright © 2011 Elsevier Inc. All rights reserved.

Entities:  

Year:  2011        PMID： 22195738      PMCID： PMC3267318          DOI： 10.1016/j.immuni.2011.12.001

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  10 in total

1.  Defining the specific physiological requirements for c-Myc in T cell development.

Authors:  N C Douglas; H Jacobs; A L Bothwell; A C Hayday
Journal:  Nat Immunol       Date:  2001-04       Impact factor: 25.606

2.  Manipulating the bioenergetics of alloreactive T cells causes their selective apoptosis and arrests graft-versus-host disease.

Authors:  Erin Gatza; Daniel R Wahl; Anthony W Opipari; Thomas B Sundberg; Pavan Reddy; Chen Liu; Gary D Glick; James L M Ferrara
Journal:  Sci Transl Med       Date:  2011-01-26       Impact factor: 17.956

3.  Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation.

Authors:  Ryan D Michalek; Valerie A Gerriets; Amanda G Nichols; Makoto Inoue; Dmitri Kazmin; Ching-Yi Chang; Mary A Dwyer; Erik R Nelson; Kristen N Pollizzi; Olga Ilkayeva; Vincent Giguere; William J Zuercher; Jonathan D Powell; Mari L Shinohara; Donald P McDonnell; Jeffrey C Rathmell
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-31       Impact factor: 11.205

4.  Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.

Authors:  Ryan D Michalek; Valerie A Gerriets; Sarah R Jacobs; Andrew N Macintyre; Nancie J MacIver; Emily F Mason; Sarah A Sullivan; Amanda G Nichols; Jeffrey C Rathmell
Journal:  J Immunol       Date:  2011-02-11       Impact factor: 5.422

5.  The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.

Authors:  Ruoning Wang; Christopher P Dillon; Lewis Zhichang Shi; Sandra Milasta; Robert Carter; David Finkelstein; Laura L McCormick; Patrick Fitzgerald; Hongbo Chi; Joshua Munger; Douglas R Green
Journal:  Immunity       Date:  2011-12-23       Impact factor: 31.745

6.  Targeting ornithine decarboxylase in Myc-induced lymphomagenesis prevents tumor formation.

Authors:  Jonas A Nilsson; Ulrich B Keller; Troy A Baudino; Chunying Yang; Sara Norton; Jennifer A Old; Lisa M Nilsson; Geoffrey Neale; Debora L Kramer; Carl W Porter; John L Cleveland
Journal:  Cancer Cell       Date:  2005-05       Impact factor: 31.743

7.  Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways.

Authors:  Sarah R Jacobs; Catherine E Herman; Nancie J Maciver; Jessica A Wofford; Heather L Wieman; Jeremy J Hammen; Jeffrey C Rathmell
Journal:  J Immunol       Date:  2008-04-01       Impact factor: 5.422

8.  Enhancing CD8 T-cell memory by modulating fatty acid metabolism.

Authors:  Erika L Pearce; Matthew C Walsh; Pedro J Cejas; Gretchen M Harms; Hao Shen; Li-San Wang; Russell G Jones; Yongwon Choi
Journal:  Nature       Date:  2009-06-03       Impact factor: 49.962

Review 9.  MYC-induced cancer cell energy metabolism and therapeutic opportunities.

Authors:  Chi V Dang; Anne Le; Ping Gao
Journal:  Clin Cancer Res       Date:  2009-10-27       Impact factor: 12.531

10.  HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.

Authors:  Lewis Z Shi; Ruoning Wang; Gonghua Huang; Peter Vogel; Geoffrey Neale; Douglas R Green; Hongbo Chi
Journal:  J Exp Med       Date:  2011-06-27       Impact factor: 14.307
  10 in total
  12 in total

1.  Peeking under the Hood of Naive T Cells.

Authors:  Wei Xu; Jonathan D Powell
Journal:  Cell Metab       Date:  2018-12-04       Impact factor: 27.287

2.  Protective Effects of Glutamine Antagonist 6-Diazo-5-Oxo-l-Norleucine in Mice with Alphavirus Encephalomyelitis.

Authors:  Sivabalan Manivannan; Victoria K Baxter; Kimberly L W Schultz; Barbara S Slusher; Diane E Griffin
Journal:  J Virol       Date:  2016-09-29       Impact factor: 5.103

Review 3.  Regulation and function of mTOR signalling in T cell fate decisions.

Authors:  Hongbo Chi
Journal:  Nat Rev Immunol       Date:  2012-04-20       Impact factor: 53.106

Review 4.  Sensing the immune microenvironment to coordinate T cell metabolism, differentiation & function.

Authors:  Emily B Heikamp; Jonathan D Powell
Journal:  Semin Immunol       Date:  2013-01-14       Impact factor: 11.130

Review 5.  Fueling the flame: bioenergy couples metabolism and inflammation.

Authors:  Tie Fu Liu; Candice M Brown; Mohamed El Gazzar; Linda McPhail; Patrick Millet; Anuradha Rao; Vidula T Vachharajani; Barbara K Yoza; Charles E McCall
Journal:  J Leukoc Biol       Date:  2012-05-09       Impact factor: 4.962

6.  BCG Vaccinations Upregulate Myc, a Central Switch for Improved Glucose Metabolism in Diabetes.

Authors:  Willem M Kühtreiber; Hiroyuki Takahashi; Ryan C Keefe; Yaerin Song; Lisa Tran; Trevor G Luck; Gabriella Shpilsky; Louisa Moore; Sarah M Sinton; Jessica C Graham; Denise L Faustman
Journal:  iScience       Date:  2020-04-21

7.  Epstein-Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection.

Authors:  Paulina Mrozek-Gorska; Alexander Buschle; Dagmar Pich; Thomas Schwarzmayr; Ron Fechtner; Antonio Scialdone; Wolfgang Hammerschmidt
Journal:  Proc Natl Acad Sci U S A       Date:  2019-07-24       Impact factor: 11.205

8.  MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages.

Authors:  Seyeon Bae; Peter Sang Uk Park; Yeji Lee; Se Hwan Mun; Eugenia Giannopoulou; Takayuki Fujii; Kelvin P Lee; Sara Nunes Violante; Justin R Cross; Kyung-Hyun Park-Min
Journal:  Cell Rep       Date:  2021-06-15       Impact factor: 9.423

9.  Molecular phenotyping of immune cells from young NOD mice reveals abnormal metabolic pathways in the early induction phase of autoimmune diabetes.

Authors:  Jian Wu; Dorothy N Kakoola; Nataliya I Lenchik; Dominic M Desiderio; Dana R Marshall; Ivan C Gerling
Journal:  PLoS One       Date:  2012-10-11       Impact factor: 3.240

10.  Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.

Authors:  Michael L Schulte; Allie Fu; Ping Zhao; Jun Li; Ling Geng; Shannon T Smith; Jumpei Kondo; Robert J Coffey; Marc O Johnson; Jeffrey C Rathmell; Joe T Sharick; Melissa C Skala; Jarrod A Smith; Jordan Berlin; M Kay Washington; Michael L Nickels; H Charles Manning
Journal:  Nat Med       Date:  2018-01-15       Impact factor: 53.440
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.