Literature DB >> 3051381

DNA diagnostics--molecular techniques and automation.

U Landegren1, R Kaiser, C T Caskey, L Hood.   

Abstract

Molecular biology has revolutionized the understanding of many aspects of human disease. Ongoing developments in DNA diagnostics--the analysis of disease at the nucleic acid level--will soon provide automated, rapid, and inexpensive analyses for DNA or RNA sequences associated with genetic, malignant, and infectious diseases. DNA diagnostics will also facilitate the identification of disease-associated genes at birth, thus creating new opportunities for preventive medicine.

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Year:  1988        PMID: 3051381     DOI: 10.1126/science.3051381

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  45 in total

1.  Full flexibility genotyping of single nucleotide polymorphisms by the GOOD assay.

Authors:  S Sauer; D Lechner; K Berlin; C Plançon; A Heuermann; H Lehrach; I G Gut
Journal:  Nucleic Acids Res       Date:  2000-12-01       Impact factor: 16.971

2.  Facile method for automated genotyping of single nucleotide polymorphisms by mass spectrometry.

Authors:  Sascha Sauer; David H Gelfand; Francis Boussicault; Keith Bauer; Fred Reichert; Ivo G Gut
Journal:  Nucleic Acids Res       Date:  2002-03-01       Impact factor: 16.971

3.  DNA amplification fingerprinting: Another diagnostic tool?

Authors:  K Rozee; W Johnson
Journal:  Can J Infect Dis       Date:  1991

4.  Automated DNA diagnostics using an ELISA-based oligonucleotide ligation assay.

Authors:  D A Nickerson; R Kaiser; S Lappin; J Stewart; L Hood; U Landegren
Journal:  Proc Natl Acad Sci U S A       Date:  1990-11       Impact factor: 11.205

5.  Colorimetric detection of specific DNA segments amplified by polymerase chain reactions.

Authors:  D J Kemp; D B Smith; S J Foote; N Samaras; M G Peterson
Journal:  Proc Natl Acad Sci U S A       Date:  1989-04       Impact factor: 11.205

6.  Genetic heterogeneity of the porphobilinogen deaminase gene in Swedish families with acute intermittent porphyria.

Authors:  J S Lee; G Lundin; L Lannfelt; L Forsell; C Picat; B Grandchamp; M Anvret
Journal:  Hum Genet       Date:  1991-08       Impact factor: 4.132

Review 7.  Disease resistance in farm animals.

Authors:  M Müller; G Brem
Journal:  Experientia       Date:  1991-09-15

Review 8.  Prenatal diagnosis of enzyme defects.

Authors:  B Winchester
Journal:  Arch Dis Child       Date:  1990-01       Impact factor: 3.791

9.  DNA polymorphisms amplified by arbitrary primers are useful as genetic markers.

Authors:  J G Williams; A R Kubelik; K J Livak; J A Rafalski; S V Tingey
Journal:  Nucleic Acids Res       Date:  1990-11-25       Impact factor: 16.971

10.  Oligonucleotides, part 5+: synthesis and fluorescence studies of DNA oligomers d(AT)5 containing adenines covalently linked at C-8 with dansyl fluorophore.

Authors:  D Singh; V Kumar; K N Ganesh
Journal:  Nucleic Acids Res       Date:  1990-06-11       Impact factor: 16.971

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