Literature DB >> 30512209

Platelet TLR4 at the crossroads of thrombosis and the innate immune response.

Mirta Schattner1.   

Abstract

Platelet TLR-4 activation by pathogen- or damage-associated molecular pattern molecules triggers pro-thrombotic, proinflammatory, and pro-coagulant effector responses. Moreover, platelet TLR4 has a prominent role as a sensor of high lipopolysaccharide circulating levels during sepsis and in the clearance of pathogens mediated by neutrophils. This review presents evidence pointing to TLR4 as a bridge connecting thrombosis and innate immunity. ©2018 Society for Leukocyte Biology.

Entities:  

Keywords:  HMGB-1; TLRs; lps; nets; platelets; sepsis; thrombosis

Mesh：

Substances：

Year:  2018        PMID： 30512209     DOI： 10.1002/JLB.MR0618-213R

Source DB:  PubMed          Journal:  J Leukoc Biol        ISSN： 0741-5400            Impact factor:   4.962


  30 in total

1.  Targeting AnxA1/Formyl Peptide Receptor 2 Pathway Affords Protection against Pathological Thrombo-Inflammation.

Authors:  Shantel A Vital; Elena Y Senchenkova; Junaid Ansari; Felicity N E Gavins
Journal:  Cells       Date:  2020-11-13       Impact factor: 6.600

Review 2.  Surgical Stress and Cancer Progression: New Findings and Future Perspectives.

Authors:  Yanghanzhao Wang; Mengdi Qu; Zhiyun Qiu; Shuainan Zhu; Wankun Chen; Kefang Guo; Changhong Miao; Hao Zhang
Journal:  Curr Oncol Rep       Date:  2022-06-28       Impact factor: 5.075

Review 3.  The emerging role of neutrophilic extracellular traps in intestinal disease.

Authors:  Feng Chen; Yongqiang Liu; Yajing Shi; Jianmin Zhang; Xin Liu; Zhenzhen Liu; Jipeng Lv; Yufang Leng
Journal:  Gut Pathog       Date:  2022-06-22       Impact factor: 5.324

4.  Human platelets display dysregulated sepsis-associated autophagy, induced by altered LC3 protein-protein interaction of the Vici-protein EPG5.

Authors:  Hansjörg Schwertz; Jesse W Rowley; Irina Portier; Elizabeth A Middleton; Neal D Tolley; Robert A Campbell; Alicia S Eustes; Karin Chen; Matthew T Rondina
Journal:  Autophagy       Date:  2021-11-18       Impact factor: 13.391

5.  Effects of bacterial lipopolysaccharides on platelet function: inhibition of weak platelet activation.

Authors:  Alexey A Martyanov; Aleksandr S Maiorov; Aleksandra A Filkova; Alexander A Ryabykh; Galina S Svidelskaya; Elena O Artemenko; Stepan P Gambaryan; Mikhail A Panteleev; Anastasia N Sveshnikova
Journal:  Sci Rep       Date:  2020-07-23       Impact factor: 4.379

Review 6.  Platelets and Intravascular Immunity: Guardians of the Vascular Space During Bloodstream Infections and Sepsis.

Authors:  Braedon McDonald; Mary Dunbar
Journal:  Front Immunol       Date:  2019-10-11       Impact factor: 7.561

7.  Reduced miR-26b Expression in Megakaryocytes and Platelets Contributes to Elevated Level of Platelet Activation Status in Sepsis.

Authors:  Bernadett Szilágyi; Zsolt Fejes; Szilárd Póliska; Marianna Pócsi; Zsolt Czimmerer; Andreas Patsalos; Ferenc Fenyvesi; Ágnes Rusznyák; György Nagy; György Kerekes; Mariann Berhés; Ildikó Szűcs; Satya P Kunapuli; János Kappelmayer; Béla Nagy
Journal:  Int J Mol Sci       Date:  2020-01-29       Impact factor: 5.923

Review 8.  The gut microbiome and thromboembolism.

Authors:  Rida Abid Hasan; Andrew Y Koh; Ayesha Zia
Journal:  Thromb Res       Date:  2020-03-06       Impact factor: 3.944

9.  Different glycoforms of alpha-1-acid glycoprotein contribute to its functional alterations in platelets and neutrophils.

Authors:  Mosale Seetharam Sumanth; Shancy P Jacob; Kandahalli Venkataranganayaka Abhilasha; Bhanu Kanth Manne; Venkatesha Basrur; Sylvain Lehoux; Robert A Campbell; Christian C Yost; Thomas M McIntyre; Richard D Cummings; Andrew S Weyrich; Matthew T Rondina; Gopal K Marathe
Journal:  J Leukoc Biol       Date:  2020-10-18       Impact factor: 4.962

Review 10.  Platelet-Monocyte Aggregates: Understanding Mechanisms and Functions in Sepsis.

Authors:  Guang Fu; Meihong Deng; Matthew D Neal; Timothy R Billiar; Melanie J Scott
Journal:  Shock       Date:  2021-02-01       Impact factor: 3.533
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.