Literature DB >> 30509493

LncRNA LCPAT1 is involved in DNA damage induced by CSE.

Sumeng Gao1, Hongyan Lin1, Wang Yu1, Fangfang Zhang1, Ruoyang Wang1, Herbert Yu2, Biyun Qian3.   

Abstract

Cigarette smoking plays an important role in the process of lung cancer, during which DNA damage is proved to be involved. Non-coding RNAs are found to be involved in the DNA damage and repair processes induced by cigarette smoke. In the present study, we investigated the role of lncRNA LCPAT1 in DNA damage caused by CSE in Beas-2B cells. Our results indicate that LCPAT1, through RCC2 is involved in the CSE-induced DNA damage providing new insight into the lung carcinogenesis related to cigarette smoking.
Copyright © 2018. Published by Elsevier Inc.

Entities:  

Keywords:  Cigarette smoke; DNA damage; LCAPT1; Lung carcinogenesis

Mesh:

Substances:

Year:  2018        PMID: 30509493     DOI: 10.1016/j.bbrc.2018.11.171

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  9 in total

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Review 8.  The role of cigarette smoke-induced epigenetic alterations in inflammation.

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Journal:  Epigenetics Chromatin       Date:  2019-11-11       Impact factor: 4.954

9.  lncRNA LCPAT1 Upregulation Promotes Breast Cancer Progression via Enhancing MFAP2 Transcription.

Authors:  Xue Gong; Tuozhou Dong; Ming Niu; Xiaoshuan Liang; Shanshan Sun; Youxue Zhang; Yue Li; Dalin Li
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  9 in total

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