Literature DB >> 30498625

Treatment of multiple system atrophy - the past, present and future.

Haiyan Yu1, Xiaoling Yuan1, Lifeng Liu1, Tian Wang2, Dianrong Gong1.   

Abstract

Multiple system atrophy is a sporadic progressive degenerative disease which is characterized by multiple central nervous systems involved. So far, there is no effective medicine to cure MSA. The main research direction of treatment includes immunization transplantation and cytotherapy. Human umbilical cord blood is the residue of blood in the placenta and umbilical cord after fetal delivery. It is the most abundant cell bank and its usage is not limited to treat hematological diseases. The researches about hUCB-MNC treatment on MSA are increasing gradually. The potential of other MSC is also discussed. Lateral atlanto-occipital space puncture is an ingenious way created by Professor Dianrong Gong. More than 30 cases of MSA have been treated by this method with fine clinical effect and without serious complications. It indicates that stem cells treatment is a valid method for refractory nerve system diseases.

Entities:  

Keywords:  Multiple system atrophy; human umbilical cord blood-mononuclear cell; lateral atlanto-occipital space puncture; stem cells

Year:  2018        PMID: 30498625      PMCID: PMC6261842     

Source DB:  PubMed          Journal:  Am J Clin Exp Immunol


  57 in total

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Authors:  Tetsutaro Ozawa
Journal:  Acta Neuropathol       Date:  2006-07-20       Impact factor: 17.088

2.  Proposed neuropathological criteria for the post mortem diagnosis of multiple system atrophy.

Authors:  J Q Trojanowski; T Revesz
Journal:  Neuropathol Appl Neurobiol       Date:  2007-12       Impact factor: 8.090

3.  Human umbilical cord blood-derived mesenchymal stem cells improve neuropathology and cognitive impairment in an Alzheimer's disease mouse model through modulation of neuroinflammation.

Authors:  Hyun Ju Lee; Jong Kil Lee; Hyun Lee; Janet E Carter; Jong Wook Chang; Wonil Oh; Yoon Sun Yang; Jun-Gyo Suh; Byoung-Hee Lee; Hee Kyung Jin; Jae-Sung Bae
Journal:  Neurobiol Aging       Date:  2010-05-14       Impact factor: 4.673

4.  Human umbilical cord blood cells express neurotrophic factors.

Authors:  Cun-Gang Fan; Qing-Jun Zhang; Feng-Wu Tang; Zhi-Bo Han; Ge-Sheng Wang; Zhong-Chao Han
Journal:  Neurosci Lett       Date:  2005-02-12       Impact factor: 3.046

5.  Repetitive hyperbaric oxygen therapy provides better effects on brain inflammation and oxidative damage in rats with focal cerebral ischemia.

Authors:  Li-Fan Chen; Yu-Feng Tian; Cheng-Hsien Lin; Lian-Yu Huang; Ko-Chi Niu; Mao-Tsun Lin
Journal:  J Formos Med Assoc       Date:  2014-04-29       Impact factor: 3.282

6.  Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome).

Authors:  M I Papp; J E Kahn; P L Lantos
Journal:  J Neurol Sci       Date:  1989-12       Impact factor: 3.181

7.  Biodistribution of bone marrow mononuclear cells after intra-arterial or intravenous transplantation in subacute stroke patients.

Authors:  Paulo Henrique Rosado-de-Castro; Felipe da Rocha Schmidt; Valeria Battistella; Sergio Augusto Lopes de Souza; Bianca Gutfilen; Regina Coeli dos Santos Goldenberg; Tais Hanae Kasai-Brunswick; Leandro Vairo; Rafaella Monteiro Silva; Eduardo Wajnberg; Pedro Emmanuel Alvarenga Americano do Brasil; Emerson Leandro Gasparetto; Angelo Maiolino; Soniza Vieira Alves-Leon; Charles Andre; Rosalia Mendez-Otero; Gabriel Rodriguez de Freitas; Lea Mirian Barbosa da Fonseca
Journal:  Regen Med       Date:  2013-03       Impact factor: 3.806

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Authors:  Gregor K Wenning; Nadia Stefanova
Journal:  J Neurol       Date:  2009-05-27       Impact factor: 4.849

9.  Second consensus statement on the diagnosis of multiple system atrophy.

Authors:  S Gilman; G K Wenning; P A Low; D J Brooks; C J Mathias; J Q Trojanowski; N W Wood; C Colosimo; A Dürr; C J Fowler; H Kaufmann; T Klockgether; A Lees; W Poewe; N Quinn; T Revesz; D Robertson; P Sandroni; K Seppi; M Vidailhet
Journal:  Neurology       Date:  2008-08-26       Impact factor: 9.910

10.  Human Gingiva-Derived Mesenchymal Stem Cells Modulate Monocytes/Macrophages and Alleviate Atherosclerosis.

Authors:  Ximei Zhang; Feng Huang; Weixuan Li; Jun-Long Dang; Jia Yuan; Julie Wang; Dong-Lan Zeng; Can-Xing Sun; Yan-Ying Liu; Qian Ao; Hongmei Tan; Wenru Su; Xiaoxian Qian; Nancy Olsen; Song Guo Zheng
Journal:  Front Immunol       Date:  2018-04-30       Impact factor: 7.561

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  2 in total

1.  Epigallocatechin gallate in multiple system atrophy (PROMESA).

Authors:  Kurt A Jellinger
Journal:  Ann Transl Med       Date:  2019-12

Review 2.  Characteristics and regulation of mesenchymal stem cell plasticity by the microenvironment - specific factors involved in the regulation of MSC plasticity.

Authors:  Liping Tan; Xuan Liu; Huan Dou; Yayi Hou
Journal:  Genes Dis       Date:  2020-10-27
  2 in total

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