Ahmed Abdel Khalek Abdel Razek1. 1. Department of Diagnostic Radiology, Faculty of Medicine, Mansoura University, 203 Elgomheryia Street, Mansoura, 13551, Egypt. arazek@mans.edu.eg.
Abstract
OBJECTIVE: This study was performed to predict malignancy of submandibular gland tumors using the apparent diffusion coefficient (ADC). METHODS: In total, 31 patients (19 male, 12 female; age, 16-71 years) with solid submandibular gland tumors were retrospectively analyzed. All patients underwent single-shot echo-planar diffusion-weighted magnetic resonance imaging of the submandibular gland region. ADC maps of the submandibular gland were reconstructed. The ADC value of the submandibular gland tumors was calculated. A freehand region of interest encompassing the homogenous tumor and solid part of the heterogeneous tumor was established. RESULTS: The mean ADC for submandibular gland malignancy (1.15 ± 0.09 × 10-3 mm2/s) was significantly lower than that for benignancy (1.55 ± 0.25 × 10-3 mm2/s, P = 0.001). An ADC of 1.26 × 10-3 mm2/s could predict malignancy of submandibular gland tumors with an area under the curve of 0.869, accuracy of 84%, sensitivity of 88%, and specificity of 81%. CONCLUSION: The ADC is a noninvasive imaging parameter that can be used for prediction of malignancy of submandibular gland tumors.
OBJECTIVE: This study was performed to predict malignancy of submandibular gland tumors using the apparent diffusion coefficient (ADC). METHODS: In total, 31 patients (19 male, 12 female; age, 16-71 years) with solid submandibular gland tumors were retrospectively analyzed. All patients underwent single-shot echo-planar diffusion-weighted magnetic resonance imaging of the submandibular gland region. ADC maps of the submandibular gland were reconstructed. The ADC value of the submandibular gland tumors was calculated. A freehand region of interest encompassing the homogenous tumor and solid part of the heterogeneous tumor was established. RESULTS: The mean ADC for submandibular gland malignancy (1.15 ± 0.09 × 10-3 mm2/s) was significantly lower than that for benignancy (1.55 ± 0.25 × 10-3 mm2/s, P = 0.001). An ADC of 1.26 × 10-3 mm2/s could predict malignancy of submandibular gland tumors with an area under the curve of 0.869, accuracy of 84%, sensitivity of 88%, and specificity of 81%. CONCLUSION: The ADC is a noninvasive imaging parameter that can be used for prediction of malignancy of submandibular gland tumors.
Entities:
Keywords:
Diffusion; Magnetic resonance imaging; Submandibular; Tumor
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