Literature DB >> 27845594

Diffusion-weighted MRI for differentiation between sialadenitis and pleomorphic adenoma.

Guilherme T C Terra1, Jefferson X D Oliveira1, Adalsa Hernandez2, Silvia V Lourenço1, Emiko S Arita1, Arthur R G Cortes1.   

Abstract

OBJECTIVES: The aim of this study was to compare apparent diffusion coefficient (ADC) values from diffusion-weighted MRI (DWI) among normal salivary glands, cases with sialadenitis and cases with pleomorphic adenoma of major salivary glands.
METHODS: 22 patients (totalling 44 major salivary glands) diagnosed with either unilateral sialadenitis (on either parotid or submandibular gland) or parotid gland pleomorphic adenoma were selected. Contralateral non-affected glands (normal) were also analyzed. DW images were achieved using a spin-echo pulse sequence with a 1.5-T MRI device. Mean ADC values were compared among the three groups analyzed (contralateral normal glands, sialadenitis and pleomorphic adenoma).
RESULTS: The mean ADC values were significantly higher in cases of parotid sialadenitis (p = 0.001), but not in cases of submandibular sialadenitis (p = 0.466), as compared with the contralateral non-affected glands. Cases of pleomorphic adenoma presented the highest ADC values of the study. In addition, one-way ANOVA test revealed a significant difference among the three groups of parotid glands analyzed.
CONCLUSIONS: Within the limitations of this study, the present results suggest that DWI allows for differentiation between parotid sialadenitis and pleomorphic adenoma.

Entities:  

Keywords:  MRI; diffusion-weighted imaging; pleomorphic adenoma; salivary glands

Mesh:

Year:  2016        PMID: 27845594      PMCID: PMC5595053          DOI: 10.1259/dmfr.20160257

Source DB:  PubMed          Journal:  Dentomaxillofac Radiol        ISSN: 0250-832X            Impact factor:   2.419


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