Literature DB >> 304826

Reduction in peripheral blood K cells and activated T cells in primary biliary cirrhosis.

G P Sandilands, R N Macsween, K G Gray, R J Holden, P Mills, F M Reid, M A Thomas, G Watkinson.   

Abstract

Lymphocyte subpopulations were measured in the peripheral blood of 13 patients with primary biliary cirrhosis (PBC), 13 with chronic active hepatitis (CAH), and 16 age- and sex-matched normal subjects. A significant, relative and absolute, reduction in activated T cells and K cells, compared with that in normal subjects, was found in PBC but not in CAH. The reduction in K cells observed in PBC was found to be accompanied by a parallel decrease in lymphocyte-mediated antibody-dependent cytotoxicity.

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Year:  1977        PMID： 304826      PMCID： PMC1411832          DOI： 10.1136/gut.18.12.1017

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  15 in total

1.  Enumeration of absolute numbers of T and B lymphocytes in human blood.

Authors:  G Brown; M F Greaves
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2.  In vitro and in vivo studies of cellular immunity in alcoholic cirrhosis.

Authors:  M R Berenyi; B Straus; D Cruz
Journal:  Am J Dig Dis       Date:  1974-03

3.  T and B lymphocytes in acute and chronic hepatitis.

Authors:  R J DeHoratius; R G Strickland; R C Williams
Journal:  Clin Immunol Immunopathol       Date:  1974-04

4.  Antibody in the induction and inhibition of lymphocyte cytotoxicity.

Authors:  I C MacLennan
Journal:  Transplant Rev       Date:  1972

Review 5.  Cell-mediated cytotoxicity, allograft rejection, and tumor immunity.

Authors:  J C Cerottini; K T Brunner
Journal:  Adv Immunol       Date:  1974       Impact factor: 3.543

6.  Antibody-dependent cell-mediated (K cell) cytotoxicity against isolated hepatocytes in chronic active hepatitis.

Authors:  A M Cochrane; A Moussouros; A D Thomsom; A L Eddleston; R Wiiliams
Journal:  Lancet       Date:  1976-02-28       Impact factor: 79.321

7.  Immunological studies in patients with chronic active hepatitis. Cytotoxic activity of lymphocytes to autochthonous liver cells grown in tissue culture.

Authors:  F Paronetto; S Vernace
Journal:  Clin Exp Immunol       Date:  1975-01       Impact factor: 4.330

8.  Lymphocyte populations in liver biopsy specimens from patients with chronic liver disease.

Authors:  J Sanchez-Tapias; H C Thomas; S Sherlock
Journal:  Gut       Date:  1977-06       Impact factor: 23.059

9.  Immunosuppressive consequences of radiotherapy and chemotherapy in patients with acute lymphoblastic leukaemia.

Authors:  A C Campbell; P Hersey; I C MacLennan; H E Kay; M C Pike
Journal:  Br Med J       Date:  1973-05-19

10.  Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells.

Authors:  M Jondal; G Holm; H Wigzell
Journal:  J Exp Med       Date:  1972-08-01       Impact factor: 14.307
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  3 in total

1.  Familial primary biliary cirrhosis associated with impaired concanavalin A-induced lymphocyte transformation in relatives. Two family studies.

Authors:  H Tsuji; K Murai; K Akagi; M Fujishima
Journal:  Dig Dis Sci       Date:  1992-03       Impact factor: 3.199

2.  Deficient natural killer cell activity in alcoholic cirrhosis.

Authors:  B Charpentier; D Franco; L Paci; M Charra; B Martin; D Vuitton; D Fries
Journal:  Clin Exp Immunol       Date:  1984-10       Impact factor: 4.330

3.  Lymphocytotoxic antibodies in primary biliary cirrhosis.

Authors:  A Parés; J Martorell; J Caballería; J Vives; M Bruguera; J Rodés
Journal:  Dig Dis Sci       Date:  1985-09       Impact factor: 3.199
  3 in total

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