Literature DB >> 30479549

Nicotinic acetylcholine receptor α6 subunit mutation (G275V) found in a spinosad-resistant strain of the flower thrips, Frankliniella intonsa (Thysanoptera: Thripidae).

Emika Hiruta1, Misato Aizawa2, Akio Nakano3, Shoji Sonoda1.   

Abstract

The flower thrips Frankliniella intonsa strain showing resistance to spinosad was established in the laboratory. The resistant strain showed an LC50 value of 1398.7 mg/L in a leaf dipping/contact assay. The LC50 value was ca. 280 times higher than that of the most susceptible strain. An insecticidal assay using synergists suggested no involvement of degradation enzymes, such as cytochrome P450, glutathione S-transferase, and carboxyl esterase, in the resistance. Glycine at amino acid position 275 of the nicotinic acetylcholine receptor (nAChR) α6 subunit was mutated to valine in the resistant strain. These results suggest that spinosad resistance in F. intonsa is conferred by the reduced sensitivity of nAChR.

Entities:  

Keywords:  Thysanoptera; flower thrips; insecticide resistance; nAChR α6 subunit; target insensitivity

Year:  2018        PMID： 30479549      PMCID： PMC6240775          DOI： 10.1584/jpestics.D18-007

Source DB:  PubMed          Journal:  J Pestic Sci        ISSN： 1348-589X            Impact factor:   1.519


  13 in total

Review 1.  Cytochromes P450 and insecticide resistance.

Authors:  J G Scott
Journal:  Insect Biochem Mol Biol       Date:  1999-09       Impact factor: 4.714

Review 2.  The molecular basis of insecticide resistance in mosquitoes.

Authors:  Janet Hemingway; Nicola J Hawkes; Lynn McCarroll; Hilary Ranson
Journal:  Insect Biochem Mol Biol       Date:  2004-07       Impact factor: 4.714

3.  The α6 nicotinic acetylcholine receptor subunit of Frankliniella occidentalis is not involved in resistance to spinosad.

Authors:  Wenjie Hou; Qiulei Liu; Lixia Tian; Qingjun Wu; Youjun Zhang; Wen Xie; Shaoli Wang; Keri San Miguel; Joe Funderburk; Jeffrey G Scott
Journal:  Pestic Biochem Physiol       Date:  2014-03-21       Impact factor: 3.963

4.  Truncated transcripts of nicotinic acetylcholine subunit gene Bdα6 are associated with spinosad resistance in Bactrocera dorsalis.

Authors:  Ju-Chun Hsu; Hai-Tung Feng; Wen-Jer Wu; Scott M Geib; Ching-hua Mao; John Vontas
Journal:  Insect Biochem Mol Biol       Date:  2012-08-05       Impact factor: 4.714

5.  Monitoring and characterization of diamondback moth (Lepidoptera: Plutellidae) resistance to spinosad.

Authors:  J Z Zhao; Y X Li; H L Collins; L Gusukuma-Minuto; R F L Mau; G D Thompson; A M Shelto
Journal:  J Econ Entomol       Date:  2002-04       Impact factor: 2.381

6.  Genetics of spinosad resistance in Frankliniella occidentalis (Thysanoptera: Thripidae).

Authors:  P Bielza; V Quinto; E Fernandez; C Grávalos; J Contreras
Journal:  J Econ Entomol       Date:  2007-06       Impact factor: 2.381

7.  Spinosad resistance of melon thrips, Thrips palmi, is conferred by G275E mutation in α6 subunit of nicotinic acetylcholine receptor and cytochrome P450 detoxification.

Authors:  Wen Xue Bao; Yutaka Narai; Akio Nakano; Takemichi Kaneda; Tamotsu Murai; Shoji Sonoda
Journal:  Pestic Biochem Physiol       Date:  2014-05-09       Impact factor: 3.963

8.  Transcripts of the nicotinic acetylcholine receptor subunit gene Pxylα6 with premature stop codons are associated with spinosad resistance in diamondback moth, Plutella xylostella.

Authors:  Frank D Rinkevich; Mao Chen; Anthony M Shelton; Jeffrey G Scott
Journal:  Invert Neurosci       Date:  2010-05-25

9.  A nicotinic acetylcholine receptor transmembrane point mutation (G275E) associated with resistance to spinosad in Frankliniella occidentalis.

Authors:  Alin M Puinean; Stuart J Lansdell; Toby Collins; Pablo Bielza; Neil S Millar
Journal:  J Neurochem       Date:  2013-01-13       Impact factor: 5.372

10.  A three amino acid deletion in the transmembrane domain of the nicotinic acetylcholine receptor α6 subunit confers high-level resistance to spinosad in Plutella xylostella.

Authors:  Jing Wang; Xingliang Wang; Stuart J Lansdell; Jianheng Zhang; Neil S Millar; Yidong Wu
Journal:  Insect Biochem Mol Biol       Date:  2016-02-06       Impact factor: 4.714
View more
  2 in total

1.  Mutation (G275E) of nAChR subunit Foα6 associated with spinetoram resistance in Australian western flower thrips, Frankliniella occidentalis (Pergande).

Authors:  Yizhou Chen; Duong T Nguyen; Risha Gupta; Grant A Herron
Journal:  Mol Biol Rep       Date:  2021-05-03       Impact factor: 2.316

2.  Increasing Frequency of G275E Mutation in the Nicotinic Acetylcholine Receptor α6 Subunit Conferring Spinetoram Resistance in Invading Populations of Western Flower Thrips in China.

Authors:  Li-Na Sun; Xiu-Jing Shen; Li-Jun Cao; Jin-Cui Chen; Li-Jun Ma; San-An Wu; Ary Anthony Hoffmann; Shu-Jun Wei
Journal:  Insects       Date:  2022-03-28       Impact factor: 2.769
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.