Literature DB >> 30473228

Proximal Femoral Allograft-Prosthetic Composites: Do They Really Restore Bone? A Retrospective Review of Revision Allograft-Prosthetic Composites.

Benjamin K Wilke1, Matthew T Houdek1, Peter S Rose1, Franklin H Sim1.   

Abstract

BACKGROUND: Large bone deficiencies are a challenging problem, historically treated with an allograft-prosthetic composite (APC) or megaprosthesis. There were several advantages of the APC compared with early megaprostheses, including the theoretical benefit of restoring bone stock. To our knowledge, there are no studies that have evaluated this claim. Our purpose was to review our institution's experience with APCs of the proximal femur that underwent revision for an aseptic cause and determine if the allograft bone was retained or removed during the revision procedure.
METHODS: We identified 203 proximal femoral allograft prosthetic composites placed from 1988 through 2014. Twenty-seven of these patients underwent a revision because of an aseptic cause. Three categories were devised to classify the amount of allograft retention: type A, complete allograft retention; type B, partial retention; and type C, no allograft retention.
RESULTS: The mean time from the initial APC to revision surgery was 5 years. The most common indication for revision included failure of the allograft (loosening or fracture). At the time of revision, there were 3 type A cases (11%), 4 type B cases (15%), and 20 type C cases (74%). Three of the 4 type B cases used the retained allograft as a strut graft around a newly inserted megaprosthesis.
CONCLUSION: The results of this study are contradictory to previous literature that suggests APCs restore bone stock. In this series, the allograft was retained in only a small percentage of cases when the APC was revised for an aseptic cause. LEVEL OF EVIDENCE: IV.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  allograft-prosthetic composites; arthroplasty; hip; proximal femur; revision

Mesh:

Year:  2018        PMID: 30473228     DOI: 10.1016/j.arth.2018.10.020

Source DB:  PubMed          Journal:  J Arthroplasty        ISSN: 0883-5403            Impact factor:   4.757


  5 in total

1.  Long-term results of uncemented allograft prosthesis composite reconstruction for the tumor in proximal femur: a minimum follow-up of sixty-five months.

Authors:  Cai Liu; Li Min; Yong Zhou; Yi Luo; Fan Tang; Minxun Lu; Hong Duan; Wenli Zhang; Xinzhu Yu; Chongqi Tu
Journal:  BMC Musculoskelet Disord       Date:  2021-02-01       Impact factor: 2.362

2.  A comparative study of autogenous, allograft and artificial bone substitutes on bone regeneration and immunotoxicity in rat femur defect model.

Authors:  Wen Zou; Xing Li; Na Li; Tianwei Guo; Yongfu Cai; Xiaoqin Yang; Jie Liang; Yong Sun; Yujiang Fan
Journal:  Regen Biomater       Date:  2020-09-30

3.  Proximal femoral replacement for non-neoplastic conditions: a systematic review on current outcomes.

Authors:  Alberto Di Martino; Davide Pederiva; Barbara Bordini; Gabriele Di Carlo; Alessandro Panciera; Giuseppe Geraci; Niccolò Stefanini; Cesare Faldini
Journal:  J Orthop Traumatol       Date:  2022-03-29

4.  Using personalized 3D printed Titanium sleeve-prosthetic composite for reconstruction of severe segmental bone loss of proximal femur in revision total hip arthroplasty: A case report.

Authors:  Xingshan Wang; Hui Xu; Ji Zhang
Journal:  Medicine (Baltimore)       Date:  2020-01       Impact factor: 1.889

5.  New 3-dimensional implant application as an alternative to allograft in limb salvage surgery: a technical note on 10 cases.

Authors:  Jong Woong Park; Hyun Guy Kang; June Hyuk Kim; Han-Soo Kim
Journal:  Acta Orthop       Date:  2020-05-12       Impact factor: 3.717

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.