Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Novel Roles for SUMOylation in Cellular Plasticity.

Literature DB >> 30463679

Novel Roles for SUMOylation in Cellular Plasticity.

Bruno Di Stefano¹, Konrad Hochedlinger².

Abstract

Cell fate transitions involve rapid changes in gene expression patterns, yet the role of post-translational modifications in these processes remains underexplored. A recent study identifies SUMOylation as a guardian of cell identity that acts during differentiation and reprogramming by reinforcing active enhancers and maintaining silenced heterochromatin in a context-specific manner.

Entities: Disease Gene Species

Mesh：

Substances：
Chromatin

Year: 2018 PMID： 30463679 PMCID： PMC6456908 DOI： 10.1016/j.tcb.2018.10.001

Source DB: PubMed Journal: Trends Cell Biol ISSN： 0962-8924 Impact factor: 20.808

10 in total

Review 1. Post-translational modifications in signal integration.

Authors: Yonathan Lissanu Deribe; Tony Pawson; Ivan Dikic
Journal: Nat Struct Mol Biol Date: 2010-05-23 Impact factor: 15.369

Review 2. Sumoylation: a regulatory protein modification in health and disease.

Authors: Annette Flotho; Frauke Melchior
Journal: Annu Rev Biochem Date: 2013 Impact factor: 23.643

3. SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States.

Authors: Jack-Christophe Cossec; Ilan Theurillat; Claudia Chica; Sabela Búa Aguín; Xavier Gaume; Alexandra Andrieux; Ane Iturbide; Gregory Jouvion; Han Li; Guillaume Bossis; Jacob-Sebastian Seeler; Maria-Elena Torres-Padilla; Anne Dejean
Journal: Cell Stem Cell Date: 2018-10-25 Impact factor: 24.633

Review 4. CRISPR/Cas9 in Genome Editing and Beyond.

Authors: Haifeng Wang; Marie La Russa; Lei S Qi
Journal: Annu Rev Biochem Date: 2016-04-25 Impact factor: 23.643

5. Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency.

Authors: Nofar Mor; Yoach Rais; Daoud Sheban; Shani Peles; Alejandro Aguilera-Castrejon; Asaf Zviran; Dalia Elinger; Sergey Viukov; Shay Geula; Vladislav Krupalnik; Mirie Zerbib; Elad Chomsky; Lior Lasman; Tom Shani; Jonathan Bayerl; Ohad Gafni; Suhair Hanna; Jason D Buenrostro; Tzachi Hagai; Hagit Masika; Gintautas Vainorius; Yehudit Bergman; William J Greenleaf; Miguel A Esteban; Ulrich Elling; Yishai Levin; Rada Massarwa; Yifat Merbl; Noa Novershtern; Jacob H Hanna
Journal: Cell Stem Cell Date: 2018-08-16 Impact factor: 24.633

Review 6. Complexity of CEBPA dysregulation in human acute myeloid leukemia.

Authors: Thomas Pabst; Beatrice U Mueller
Journal: Clin Cancer Res Date: 2009-08-25 Impact factor: 12.531

7. SUMO2 is essential while SUMO3 is dispensable for mouse embryonic development.

Authors: Liangli Wang; Carolien Wansleeben; Shengli Zhao; Pei Miao; Wulf Paschen; Wei Yang
Journal: EMBO Rep Date: 2014-06-02 Impact factor: 8.807

8. Detecting endogenous SUMO targets in mammalian cells and tissues.

Authors: Janina Becker; Sina V Barysch; Samir Karaca; Claudia Dittner; He-Hsuan Hsiao; Mauricio Berriel Diaz; Stephan Herzig; Henning Urlaub; Frauke Melchior
Journal: Nat Struct Mol Biol Date: 2013-03-17 Impact factor: 15.369

9. The histone chaperone CAF-1 safeguards somatic cell identity.

Authors: Sihem Cheloufi; Ulrich Elling; Barbara Hopfgartner; Youngsook L Jung; Jernej Murn; Maria Ninova; Maria Hubmann; Aimee I Badeaux; Cheen Euong Ang; Danielle Tenen; Daniel J Wesche; Nadezhda Abazova; Max Hogue; Nilgun Tasdemir; Justin Brumbaugh; Philipp Rathert; Julian Jude; Francesco Ferrari; Andres Blanco; Michaela Fellner; Daniel Wenzel; Marietta Zinner; Simon E Vidal; Oliver Bell; Matthias Stadtfeld; Howard Y Chang; Genevieve Almouzni; Scott W Lowe; John Rinn; Marius Wernig; Alexei Aravin; Yang Shi; Peter J Park; Josef M Penninger; Johannes Zuber; Konrad Hochedlinger
Journal: Nature Date: 2015-12-10 Impact factor: 49.962

10. A Serial shRNA Screen for Roadblocks to Reprogramming Identifies the Protein Modifier SUMO2.

Authors: Marti Borkent; Brian D Bennett; Brad Lackford; Ori Bar-Nur; Justin Brumbaugh; Li Wang; Ying Du; David C Fargo; Effie Apostolou; Sihem Cheloufi; Nimet Maherali; Stephen J Elledge; Guang Hu; Konrad Hochedlinger
Journal: Stem Cell Reports Date: 2016-03-03 Impact factor: 7.765

10 in total

1 in total

1. p53 SUMOylation Mediates AOPP-Induced Endothelial Senescence and Apoptosis Evasion.

Authors: Yanjia Chen; Zhuanhua Liu; Hongyu Chen; Xingfu Huang; Xiaoxia Huang; Yang Lei; Qing Liang; Jiayi Wei; Qin Zhang; Xiaohua Guo; Qiaobing Huang
Journal: Front Cardiovasc Med Date: 2022-02-03

1 in total