| Literature DB >> 30454767 |
Tony L Yaksh1, Matthew A Hunt2, Gilson G Dos Santos2.
Abstract
Management of pain is a fundamental imperative in medicine. Current analgesics suffer from limitations related to efficacy and adverse events of which abuse potential has assumed an important role. Here we highlight the factors that drive the development of novel analgesics and the advances made in the field.Entities:
Keywords: analgesics; dependence; drug abuse; tolerance
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Year: 2018 PMID： 30454767 DOI： 10.1016/j.tips.2018.10.003
Source DB: PubMed Journal: Trends Pharmacol Sci ISSN： 0165-6147 Impact factor: 14.819