Literature DB >> 30450631

Changing trends in management of vestibular schwannoma: A National Cancer Database study.

Bassel Bashjawish1, Suat Kılıç1, Soly Baredes1,2, Jean Anderson Eloy1,3,4,5, James K Liu4, Yu-Lan Mary Ying1.   

Abstract

OBJECTIVE: To describe changes in management trends of vestibular schwannoma (VS) and the effects of median income, education level, insurance status, and tumor size on receipt of treatment.
METHODS: Cross-sectional analysis using the National Cancer Database from 2004 to 2014. All patients with a diagnosis of VS were identified between 2004 and 2014. Trends in treatment modality over time were analyzed. Correlation between demographics, institution type, median income, education level, and insurance status were assessed using univariate and multivariate logistic regressions.
RESULTS: Of the 22,290 VS patients identified, 16,011 (71.8%) received treatment, whereas 6,279 (28.2%) received observation. Management trend analysis over the 11-year period revealed patients with tumor size < 1 cm are more frequently observed (34.6% of cases in 2004 vs. 60.8% of cases in 2014) and less frequently received surgery (34.6% vs. 16.8%). Multivariate analysis showed observation was more frequently used in patients ≥ 65 years; black patients; and those on Medicaid, Medicare, and noninsured (P < 0.0001). All tumors > 2 cm were more likely to be treated with surgery, specifically subtotal resections (P < 0.0001). Patients treated at nonacademic centers were more likely to receive linear accelerator, or LINAC (Accuray Incorporated, Sunnyvale, CA) therapy than Gamma Knife (Elekta, Stockholm, Sweden) (P < 0.0001).
CONCLUSION: Management of VS is shifting toward increased observation, most significantly in tumors size < 1 cm. Insurance provider plays a significant role on receipt of treatment and modality, whereas income and education do not. LEVEL OF EVIDENCE: NA Laryngoscope, 129:1197-1205, 2019.
© 2018 The American Laryngological, Rhinological and Otological Society, Inc.

Entities:  

Keywords:  National Cancer Database; Vestibular schwannoma; microsurgery; stereotactic radiosurgery

Mesh:

Year:  2018        PMID: 30450631     DOI: 10.1002/lary.27568

Source DB:  PubMed          Journal:  Laryngoscope        ISSN: 0023-852X            Impact factor:   3.325


  4 in total

Review 1.  Assessing the long-term safety and efficacy of gamma knife and linear accelerator radiosurgery for vestibular schwannoma: A systematic review and meta-analysis.

Authors:  Sergio W Guadix; Alice J Tao; Anjile An; Michelle Demetres; Umberto Tosi; Swathi Chidambaram; Jonathan P S Knisely; Rohan Ramakrishna; Susan C Pannullo
Journal:  Neurooncol Pract       Date:  2021-08-13

2.  Treatment Analysis and Overall Survival Outcomes of Patients With Bilateral Vestibular Schwannoma.

Authors:  Khodayar Goshtasbi; Mehdi Abouzari; Tyler M Yasaka; Sina Soltanzadeh-Zarandi; Brooke Sarna; Harrison W Lin; Hamid R Djalilian
Journal:  Otol Neurotol       Date:  2021-04-01       Impact factor: 2.619

3.  Underreporting of Vestibular Schwannoma Incidence Within National Brain Tumor and Cancer Registries in the United States.

Authors:  John P Marinelli; Ashley M Nassiri; Elizabeth B Habermann; Christine M Lohse; Sara J Holton; Matthew L Carlson
Journal:  Otol Neurotol       Date:  2021-07-01       Impact factor: 2.619

4.  Middle-ear cholesteatoma co-existing with labyrinthine fistula and vestibular schwannoma.

Authors:  Aleksander Zwierz; K Masna; P Burduk
Journal:  Eur Arch Otorhinolaryngol       Date:  2020-01-23       Impact factor: 2.503

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.