Kelly K Anderson1, Suzanne Archie2, Richard G Booth3, Chiachen Cheng4, Daniel Lizotte5, Arlene G MacDougall6, Ross M G Norman7, Bridget L Ryan8, Amanda L Terry8, Rebecca Rodrigues9. 1. Assistant Professor, Department of Epidemiology & Biostatistics, Schulich School of Medicine & Dentistry, The University of Western Ontario and Department of Psychiatry, Schulich School of Medicine & Dentistry, The University of Western Ontario and Mental Health and Addictions Group, Institute for Clinical Evaluative Sciences, Canada. 2. Associate Professor, Department of Psychiatry and Behavioural Neurosciences, McMaster University, Canada. 3. Assistant Professor, Arthur Labatt Family School of Nursing, The University of Western Ontario, Canada. 4. Assistant Professor, Department of Psychiatry, Northern Ontario School of Medicine, Canada. 5. Assistant Professor, Department of Epidemiology & Biostatistics, Schulich School of Medicine & Dentistry, The University of Western Ontario and Department of Computer Science, The University of Western Ontario, Canada. 6. Assistant Professor, Department of Epidemiology & Biostatistics, Schulich School of Medicine & Dentistry, The University of Western Ontario and Department of Psychiatry, Schulich School of Medicine & Dentistry, The University of Western Ontario, Canada. 7. Professor Emeritus, Department of Epidemiology & Biostatistics, Schulich School of Medicine & Dentistry, The University of Western Ontario and Department of Psychiatry, Schulich School of Medicine & Dentistry, The University of Western Ontario, Canada. 8. Assistant Professor, Department of Epidemiology & Biostatistics, Schulich School of Medicine & Dentistry, The University of Western Ontario and Centre for Studies in Family Medicine, Schulich School of Medicine & Dentistry, The University of Western Ontario, Canada. 9. Project Coordinator, Department of Epidemiology & Biostatistics, Schulich School of Medicine & Dentistry, The University of Western Ontario, Canada.
Abstract
BACKGROUND: The family physician is key to facilitating access to psychiatric treatment for young people with first-episode psychosis, and this involvement can reduce aversive events in pathways to care. Those who seek help from primary care tend to have longer intervals to psychiatric care, and some people receive ongoing psychiatric treatment from the family physician. AIMS: Our objective is to understand the role of the family physician in help-seeking, recognition and ongoing management of first-episode psychosis. METHOD: We will use a mixed-methods approach, incorporating health administrative data, electronic medical records (EMRs) and qualitative methodologies to study the role of the family physician at three points on the pathway to care. First, help-seeking: we will use health administrative data to examine access to a family physician and patterns of primary care use preceding the first diagnosis of psychosis; second, recognition: we will identify first-onset cases of psychosis in health administrative data, and look back at linked EMRs from primary care to define a risk profile for undetected cases; and third, management: we will examine service provision to identified patients through EMR data, including patterns of contacts, prescriptions and referrals to specialised care. We will then conduct qualitative interviews and focus groups with key stakeholders to better understand the trends observed in the quantitative data. DISCUSSION: These findings will provide an in-depth description of first-episode psychosis in primary care, informing strategies to build linkages between family physicians and psychiatric services to improve transitions of care during the crucial early stages of psychosis. DECLARATION OF INTEREST: None.
BACKGROUND: The family physician is key to facilitating access to psychiatric treatment for young people with first-episode psychosis, and this involvement can reduce aversive events in pathways to care. Those who seek help from primary care tend to have longer intervals to psychiatric care, and some people receive ongoing psychiatric treatment from the family physician. AIMS: Our objective is to understand the role of the family physician in help-seeking, recognition and ongoing management of first-episode psychosis. METHOD: We will use a mixed-methods approach, incorporating health administrative data, electronic medical records (EMRs) and qualitative methodologies to study the role of the family physician at three points on the pathway to care. First, help-seeking: we will use health administrative data to examine access to a family physician and patterns of primary care use preceding the first diagnosis of psychosis; second, recognition: we will identify first-onset cases of psychosis in health administrative data, and look back at linked EMRs from primary care to define a risk profile for undetected cases; and third, management: we will examine service provision to identified patients through EMR data, including patterns of contacts, prescriptions and referrals to specialised care. We will then conduct qualitative interviews and focus groups with key stakeholders to better understand the trends observed in the quantitative data. DISCUSSION: These findings will provide an in-depth description of first-episode psychosis in primary care, informing strategies to build linkages between family physicians and psychiatric services to improve transitions of care during the crucial early stages of psychosis. DECLARATION OF INTEREST: None.
Entities:
Keywords:
First-episode psychosis; early intervention; family physician; pathways to care; primary care
Evidence suggests that timely and adequate management of the first episode of psychosis is a
clinical imperative. Providing rapid access to psychiatric treatment can prevent unnecessary
suffering of patients and their family members, as well as prevent the negative social,
educational and occupational consequences associated with untreated psychosis. Evidence from
systematic reviews suggest that delays in the treatment of psychosis are associated with poor
clinical and functional outcomes,, and
outcome trajectories are typically determined in the 2-year period following the first
episode, making the early stages of
psychotic disorder a critical period for detection and intervention. This evidence has led to
the widespread implementation of early psychosis intervention (EPI) services, reflecting
optimism about prospects for recovery if comprehensive services are offered early in the
course of illness.The emphasis on early detection and reduction of treatment delay in first-episode psychosis
has led to an increased interest in pathways to care. The Goldberg and Huxley model has been proposed as a framework to
describe the process of seeking mental healthcare. This model proposes that there are four
‘filters’ between five levels of care, and patient characteristics, clinical features,
physician attributes and systemic barriers influence whether a person will progress from one
level to the next. The first level of the
model is the community, where a considerable number of people suffer from psychiatric symptoms
or psychological distress. At the second
level are the subset of symptomatic people who seek help from a family physician. When symptomatic people do seek healthcare,
the family physician may only identify psychiatric illness in a subset of patients, which
comprises the third level. The fourth level consists of people who are diagnosed as having a
psychiatric disorder and are referred to mental health services, and the fifth level includes
people who present to mental health services and are subsequently admitted to hospital for
more intensive in-patient care.
The family physician and pathways to care
Research on the pathways to care of young people with first-episode psychosis presents a
more complex picture of the types and sequence of contacts than the model proposed by
Goldberg and Huxley, with circuitous routes to care, cycling within and between services
and heavy use of the emergency department and in-patient admissions.,–
Within this complexity, the family physician continues to be a key player in these
pathways to mental healthcare. More specifically, approximately 30% of young people with
first-episode psychosis in Ontario (Canada) receive their first diagnosis of psychosis
from a family physician. An additional 30% who were diagnosed in secondary or tertiary
care had mental health contacts with a family physician in the 6-month period before the
first diagnosis of psychosis. This
indicates that the majority of young people with early psychosis are making help-seeking
contacts for mental health problems in primary care.Additionally, young people with the early signs of psychosis who initiate their own
help-seeking (as opposed to family or friends on their behalf) are more likely to seek
help from a family physician than from psychiatric or emergency services. This indicates that family physicians
may see these young people when they are at an earlier stage of illness and motivated by a
subjective need for help, and thus more amenable to engaging in treatment.Involvement of a family physician on the pathway to care also reduces the likelihood of
negative and aversive pathways to care, such as via police, ambulance and the emergency
department,,, and reduces the likelihood of subsequent in-patient
admission. Increasing family
physician involvement in the identification and management of young people with early
psychosis would be beneficial for improving service-related outcomes.Moreover, young people with first-episode psychosis who seek help from a family physician
tend to have a longer period of time before first contact with a psychiatrist and a
greater number of help-seeking contacts, relative to young people with psychosis who
present to services elsewhere.,
This may indicate problems with referrals and wait times, or may indicate that family
physicians are having difficulty recognising and responding to these patients.Finally, a substantial proportion of young people with psychosis in Ontario are not
accessing EPI services and are receiving ongoing psychiatric treatment in primary
care. We do not have information
on the care being provided to these patients – this could indicate gaps in EPI service
provision or may suggest that a subset of patients do well in primary care and do not need
the more intensive and specialised care offered by EPI programmes.
The family physician and early psychosis
Although these findings highlight the importance of the family physician in pathways to
care, they are unable to provide explanations for the observed trends. Surveyed family
physicians estimate that they see one or two patients per year with the signs of early
psychosis,– and physicians with poor knowledge of
the core signs of first-episode psychosis are more likely to report that they did not see
any patients in the previous year suspected to be in the early phases of a psychotic
disorder. Many primary care
clinicians report lacking confidence in their diagnostic skills for first-episode
psychosis because of the fluctuating nature of symptoms and the high prevalence of
subthreshold psychosis in the community. Indeed, international research using health administrative data
has shown increased use of primary care services up to 6 years before a first diagnosis of
psychosis. These help-seeking
contacts may have occurred during the putative ‘prodromal phase’ that precedes
first-episode psychosis, which is characterised by a heterogeneous pattern of symptoms,
including depressed mood, anxiety, sleep disturbance, social withdrawal, deterioration in
functioning and irritability. When
the signs of early psychosis are recognised by family physicians, there may be uncertainty
regarding how to proceed, and some report they lack the requisite skills and knowledge for
dealing with people with serious mental illness and perceive these patients as too
specialised for primary care. Family
physicians report that they rarely initiate antipsychotic treatment in a suspected case of
first-episode psychosis, and instead prefer a psychiatric referral or consultation to
confirm the diagnosis.,
Organising a prompt referral to specialised services may not always be straightforward:
nearly half of family physicians in a large survey reported only referring suspected cases
when the referral is requested or accepted by the patient or when the diagnostic picture
becomes clear, and family physicians
report that the delay that arises from convincing reluctant patients to accept a referral
can be longer than a month for nearly half of all cases. Family physicians also report delays obtaining a rapid referral
because of inaccessibility of mental health services and a lack of communication with
psychiatrists,, and even when referrals are
successfully initiated, many family physicians report that a substantial number of
patients are lost to follow-up between primary and secondary services. Finally, less than half of young people
with psychotic disorders who are receiving care from specialised services have ongoing
contact with primary care services.
This concurrent contact is needed to monitor risk factors associated with psychotic
disorders and antipsychotic treatment, such as smoking and obesity, and to manage medical
comorbidities.
Rationale
Because first-episode psychosis is a relatively rare occurrence in primary care, the
importance of the family physician in early detection and intervention has been
underestimated; further, it has been argued that EPI services need to more actively engage
with the primary care sector to ensure success. However, there is a notable lack of literature on patterns of
primary care use for young people with first-episode psychosis. Most prior research has
used surveys of family physicians, which are unable to provide an accurate picture of
clinical activities, service provision and the factors leading to patients who go
undiagnosed in the primary care system. Of exception, two prior studies have used health
administrative data to look at help-seeking from a family physician before the first
diagnosis of psychosis,,
but health administrative data alone does not yield information on the reasons behind
observed trends.It is evident that there is a need to support family physicians in the important role
that they play in the help-seeking process of young people with first-episode psychosis. A
number of studies have attempted to intervene at the level of primary care to improve
detection and referral rates, and the results of these interventions have been equivocal:
some studies,,, but not all, have found that family physician education increases referrals
to secondary care, but other evidence suggests that education alone is unlikely to
substantially improve detection and referral rates. Recent evidence from the UK has found that an intensive liaison
between primary and secondary care is both effective and cost-effective for improving
detection rates of early psychosis.
To more effectively design and implement initiatives to support family physicians in this
role, we need a thorough understanding of the underlying reasons for the trends currently
observed in primary care.
Method
The overall goal of this study is to understand the role of the family physician and
primary care services in the help-seeking process, recognition and ongoing management of
young people with first-episode psychosis. This project will use a mixed-methods approach,
specifically a sequential explanatory design that uses qualitative data to help explain or
expand upon significant or anomalous trends observed in quantitative findings. For each of the proposed objectives, we
will use population-based health administrative data and/or electronic medical records
(EMRs) to provide quantitative information. Following analyses of these data, we will
conduct qualitative interviews and focus groups with key stakeholders to better understand
the trends we observe in the quantitative data.
Ethics approval and consent to participate
The Institute for Clinical Evaluative Sciences (ICES) is a prescribed entity under
section 45 of Ontario's Personal Health Information Protection Act. Section 45 is the
provision that enables analysis and compilation of statistical information related to the
management, evaluation and monitoring of, allocation of resources to, and planning for the
health system. Section 45 authorizes health information custodians to disclose personal
health information to a prescribed entity, like ICES, without consent for such purposes.
The portions of this protocol that involve health administrative and EMR data do not
require review by a research ethics board. Ethics approval for the qualitative portion of
the study will be sought in the final year of the project.
Availability of data and materials
The data-set from this study will be held securely in coded form at ICES and the ICES
analyst will have full access to study data. Although data-sharing agreements prohibit
ICES from making the data-set publicly available, access can be granted to those who meet
prespecified criteria for confidential access, available at www.ices.on.ca/DAS. The
full data-set creation plan is available from the authors upon request.
Study objectives
The objectives addressed in this study will be guided by the first three filters that
involve primary care in Goldberg and Huxley's pathways-to-care framework:Pathway filter 1: help-seeking in primary
care. Our first objective is to describe help-seeking from primary care for young
people with early psychosis, specifically the proportion of people with
first-episode psychosis who have access to a regular family physician, and whether
these people have distinct patterns of help-seeking in primary care before a first
episode of psychosis.Pathway filter 2: recognition by
primary care. Our second objective is to identify people with first-episode
psychosis who were diagnosed in secondary and tertiary care but had prior
help-seeking contacts in primary care, with an aim of identifying a risk profile for
prodromal or early cases in primary care.Pathway
filter 3: management by primary care. Our third objective is to describe the
practise patterns and ongoing care provided to young people with first-episode
psychosis in primary care.Following these quantitative analyses, we will conduct a series of qualitative interviews
with various stakeholders, to describe (i) the experiences of young people with
first-episode psychosis when seeking help from primary care for their early symptoms of
psychosis, including facilitators or barriers to help-seeking from a family physician;
(ii) the experiences of family physicians in recognising and diagnosing early psychosis in
primary care, and any additional supports that may be needed to manage cases of
first-episode psychosis in primary care and (iii) the perceptions of clinicians at EPI
programmes on barriers and opportunities for providing collaborative care with family
physicians.
Source of quantitative data
Each of the three phases of the study will involve analyses of the data holdings at ICES,
which has an extensive repository of linked health administrative data from the publicly
funded Ontario Health Insurance Plan (OHIP), with access to data from physician billings,
hospital admissions and ambulatory care visits. There are also data derived from the EMRs
of more than 350 family physicians from across Ontario, representing over 500 000 patients
in urban, suburban and rural areas of the province. This database is fully linkable to the
health administrative data by encrypted health insurance numbers. The ICES data holdings
include the entire population of Ontario with valid OHIP coverage, with information dating
as far back as 1988.
Pathway filter 1: help-seeking in primary care
Research questions
Our first research question is, what proportion of young people with first-episode
psychosis have access to a regular family physician, and what sociodemographic and
clinical factors are associated with a lack of access? Our second research question is,
do people with first-episode psychosis have distinctive patterns of help-seeking within
primary care preceding the first diagnosis, relative to the general population?
Hypotheses
We hypothesize that young people with first-episode psychosis will be less likely to
have access to a regular family physician, and that access will vary by sociodemographic
and clinical factors. We also hypothesize that, among people who do have access to a
regular family physician, those with first-episode psychosis will demonstrate elevated
and increasing help-seeking attempts in the 6-year period preceding the index diagnosis
of psychosis, and have a greater proportion of help-seeking attempts for mental health
reasons, relative to the general population.
Study design
We will construct a retrospective cohort composed of Ontario residents aged 14–35 years
between 2005 and 2015. This age group is considered a priority population by the Ontario
Ministry of Health and Long-Term Care, and this time period corresponds to the rollout of EPI programmes
across the province.
Case status
New cases of psychotic disorder will be identified by a primary discharge diagnosis of
non-affective psychosis (e.g. schizophrenia, schizoaffective disorder, schizophreniform
disorder, psychosis not otherwise specified) from a hospital bed, or at least two OHIP
billing claims or emergency department visits with a diagnostic code for non-affective
psychosis in any 12-month period. This algorithm has been previously validated at ICES,
using medical charts. People with
a history of service contact for psychosis before 2005 will be considered prevalent
cases and will be removed.
Assignment of family physicians
Each person in the cohort will be assigned to a family physician with the Client Agency
Program Enrolment tables at ICES, which is a database of patients rostered to each
family physician practising in a patient enrolment model. For family physicians not
practising in these models, a ‘virtual roster’ method will be used, which assigns
non-rostered patients to the family physician who had the highest value of billings for
18 core primary care OHIP fee codes in the previous 2 years. This method has been shown
to have high levels of concordance (>80%) with self-report measures of access to
primary care. All remaining people
will be considered to have no regular family physician.
Covariates
Available sociodemographic variables include age, gender, income quintile,
marginalisation index, rural place of residence, ethnicity and immigrant status. We will
also construct indicator variables to reflect the presence of other psychiatric or
medical comorbidities that may affect access to primary care, such as history of
diagnosis of a substance-related disorder or diabetes.
Analysis 1
We will estimate the proportion of young people with newly diagnosed psychosis who do
not have regular access to a family physician, and compare this with young people in the
general population. We will use multivariate logistic regression to model whether
subgroups of young people with psychotic disorder (such as those with rural residence
and ethnic minorities) are less likely to have regular access to a family physician.
Analysis 2
This portion of the analysis will be restricted to young people who are enrolled or
virtually rostered with a family physician. We will conduct a case–control analysis,
using the population-based control group of young people who do not have a psychotic
disorder. Cases will be matched to controls at a ratio of 1:2, based on age (±1 year),
gender and rural residence at the diagnosis date of the corresponding case. We will
compare the pattern of primary care visits between cases and controls for the 6-year
preceding period, using negative binomial regression models with robust variance
estimators to account for the matched design.
Sample size
Our previous 10-year cohort of young people aged 14–35 years in Ontario with a first
diagnosis of psychotic disorder included over 20 000 people, and our proposed matching procedure will give us a
control group of 40 000 people. This sample size is more than sufficient to detect small
differences in parameter estimates between groups (e.g. rate ratios of 1.1 detected with
100% power at a 99% confidence level).
Outputs
These analyses will allow us to determine whether young people with a first episode of
psychotic disorder have differential access to a regular family physician, as has been
found among people with chronic psychotic disorders, and whether this access differs by sociodemographic or
clinical factors. It will also enable an exploration of whether young people with
psychotic disorders show different patterns of help-seeking from primary care in the
period leading up to the first diagnosis, as observed in other jurisdictions.
Pathway filter 2: recognition by primary care
Our first research question is, what proportion of young people with first-episode
psychosis were diagnosed in secondary and tertiary care but had prior help-seeking
contacts in primary care? Our second research question is, can we identify a risk
profile for prodromal or early cases in primary care?We hypothesize that patient characteristics such as age and gender, as well as
physician characteristics such as graduation year and panel size, will be associated
with detection of the early signs of psychosis in primary care. We also hypothesize that
a distinct profile of primary care help-seeking will emerge, based on presenting
symptoms and other characteristics, that will enable us to identify a risk profile to
aid in early detection in the primary care context.We will link the cohort created in the previous analysis to the Electronic Medical
Record Administrative Data Linked Database (EMRALD), which includes EMR data from over
350 family physicians. This linkage will allow us to identify cases of first-episode
psychosis in the health administrative data, using a validated algorithm, and then look back in EMR data for
more detailed information on prior mental health help-seeking attempts from the family
physician. The sample will be restricted to people who are in the EMRALD database with
prior contacts in primary care.
Outcome classification
The sample will be divided into two groups: (i) people who received the index diagnosis
of psychosis in primary care and (ii) people who were diagnosed in secondary or tertiary
care, but who had prior help-seeking attempts in primary care.
Patient-level covariates
Available variables include age, gender, income quintile, marginalisation index, rural
place of residence, ethnicity, immigrant status and psychiatric and medical
comorbidities.
Physician-level covariates
Available variables include age, gender, years since graduation, rurality of practice,
practice model (e.g. fee for service, family health team, etc.) and practice size.Multilevel logistic regression, with physician as the clustering unit, will be used to
model the patient and physician characteristics associated with first diagnosis in
primary care.We will use machine-learning techniques to define a risk profile for people in primary
care who may be experiencing prodromal or early signs of psychotic disorder but go
undiagnosed by the family physician. We will use predictive modelling techniques from
machine learning (such as decision trees), informed by established criterion characterising the prodrome
to psychosis, to look at
presenting symptoms and other visit characteristics to identify subgroups of young
people who are most likely to receive a subsequent diagnosis of psychosis.Using a local EMR database, exploratory pilot analyses suggest primary care physicians
have a mean of 2.4 young people with early psychosis on their roster. Extrapolating to
the EMRALD database, we expect approximately 750 diagnosed cases in primary care. We are
unable to determine the number of undiagnosed cases, but prior research suggests that
approximately 30% of young people with first-episode psychosis are diagnosed by a family
physician and an additional 30% had primary care mental health contacts in the 6 months
preceding the index diagnosis.
Based on our estimates for the number of diagnosed cases, we anticipate an additional
750 undiagnosed cases in the EMR data, for a total sample of 1500 people. This sample
size will allow us to detect odds ratios of 1.2–1.3, with 80% power at a 95% confidence
level. This sample size is also sufficient for the machine-learning analyses, where the
general criterion is that at least ten cases are needed per variable considered in the
decision-tree analysis.These analyses will allow us to determine whether patient-, physician- or
practice-level characteristics are associated with diagnosis of early psychosis in
primary care, and to identify a risk profile of early psychosis in primary care to aid
family physicians in identification.
Pathway filter 3: management by primary care
Our first research question is, how do family physicians manage cases of first-episode
psychosis identified in primary care? Our second research question is, what are their
practise patterns with respect to prescription of psychotropic medication, referral to
specialised services and ongoing management?We hypothesize that groups who tend to be underrepresented in EPI programmes, such as women, people who are older
at first onset of symptoms and recent migrant groups, will be more likely to be managed
within primary care. We also expect that among people who are referred to specialised
services, there will be little ongoing management of physical or mental health concerns
in the primary care context.Using the subgroup of patients with first-episode psychosis in the EMRALD database who
are diagnosed in primary care, we will conduct a prospective cohort study of primary
care contacts for the 12-month period after the index diagnosis of psychosis.
Outcome measures
Data will be extracted from the EMRALD database on frequency of contacts, prescription
of psychotropic medication and referral to specialised care.
Analysis
To identify common practise patterns, we will use clustering techniques from the
machine-learning literature to identify management practises that tend to co-occur
within the population of family physicians (e.g. perhaps psychotropic medication and
referral to specialist are often used separately and seldom used together), as well as
practise patterns that are seldom or never used. We will also use a bi-clustering
technique (sometimes called co-clustering or block clustering) to simultaneously identify subgroups of family
physicians who have similar practise patterns based on available data, and subgroups of
patients more likely to be managed in primary care.As described in the previous section, we expect our sample to include approximately 750
cases diagnosed in primary care. This sample size is sufficient for the machine-learning
analyses, where the general criterion is that at least ten cases are needed per variable
considered in the bi-clustering procedure.These analyses will provide information on the practise patterns of family physicians
when managing first-episode psychosis in primary care, whether particular subgroups of
patients are more likely to be receiving ongoing primary care and whether subgroups of
family physicians may require additional supports to manage these patients.
Qualitative methods
The research questions will be driven by the results of the quantitative analyses, and
will seek explanations for observed trends. We will additionally address the following
research questions: What are the experiences of young people with first-episode
psychosis in seeking help from primary care for their early symptoms of psychosis? What
do they identify as facilitators or barriers to help-seeking from their family
physician? What are the experiences of family physicians in recognising and diagnosing
early psychosis in primary care? What supports and resources do family physicians
require to manage cases of first-episode psychosis? What do family physicians see as
their role in caring for patients with first-episode psychosis after they have been
referred and accepted into an EPI programme? And finally, what do intake workers and
clinicians at EPI programmes identify as barriers and opportunities for providing
collaborative care with family physicians?
Qualitative approach
We will use a qualitative descriptive approach, which is aimed at producing a
comprehensive summary of the phenomenon. This approach was chosen for the proposed analysis because it is
particularly suited to mixed-methods designs and is relevant in health services research
for improving the potential utility and uptake of the findings.,
Sampling
Maximum variation sampling will be used to select clients from participating EPI sites
by gender (demographic variation) and whether they were referred by a family physician
(phenomenal variation). For the
family physician interviews, we will approach primary care physicians from the
professional networks of study team members. Maximum variation sampling will again be
used to select family physicians by gender, years since graduation, practice model, and
urban versus rural practice location. Finally, we will conduct one focus group per
participating EPI site (n = 6), consisting of a range of clinicians,
including intake coordinators, case managers and psychiatrists.
Data collection
Data will be collected by semistructured in-depth interviews, which use an open-ended,
conversational technique that focuses on the participants' experience and understanding
of an event. The main interview
questions will be developed a priori, based on findings from the
quantitative analyses, and incorporated into interview guides that will be used as an
outline and to probe areas of interest. All participants will be asked a set of core questions informed
from the quantitative data to identify recurring themes in qualitative responses to
specific inquiries. Three versions of the interview guide will be developed and tailored
to the stakeholder being interviewed. Interviews will be conducted by telephone for
clients and family physicians, which has been shown to yield similar findings to
face-to-face interviews, and via
focus group for EPI clinicians. All participants will receive a token for their
contribution in the form of gift cards for clients, cash for physicians and lunch for
EPI clinicians.Thematic analysis is the recommended technique for qualitative descriptive studies, as
it is less interpretive and focuses on summarising the findings with data-derived codes
or themes. We will use
conventional content analysis, which involves reducing the data into smaller segments or
codes, based on the concepts that are represented, and then grouping the material based
on shared concepts. Initial coding
will be undertaken individually by three members of the research team. Preliminary
interpretations of the qualitative data will then be compared and contrasted, and
discussed thoroughly until consensus in the coding structure is achieved. The
trustworthiness and validation of preliminary findings will be established through this
process of systematic, team-based data analysis. Further, the emergent codes will also
be refined and modified over the course of the analytic process by the larger research
team as new insights are gained that require re-examination of the data.We expect to recruit 20–30 young people with first-episode psychosis (four or five per
site) and 20–30 physicians, based on previous studies that used a qualitative
descriptive approach. We will
conduct one focus group at each of the six participating sites, and will aim to include
six to ten clinicians per focus group. These are estimated sample sizes, as sampling
will occur until maximum variation has been obtained and until the data reaches
saturation, which is the point when no additional insights are gained from further data
collection efforts.Interviews with clients will provide descriptions of the motivations and experiences of
seeking or not seeking help for psychosis in primary care. Interviews with family
physicians will yield in-depth knowledge of their comfort level in recognising and
diagnosing psychosis in primary care, and the support required to improve capacity and
collaborations with psychiatry. Qualitative focus groups with EPI clinicians will allow
us to identify challenges and opportunities for improving transitions of care and
collaborations between primary care and EPI programmes.
Discussion
There is a lack of research on the role of the family physician in EPI. Individually,
family physicians may only see a small number of cases of early psychosis per year, but
collectively they represent an important access point for psychiatric care. We are proposing
to harness the power of this collective by using population-based health administrative
data, fully linkable to EMRs from primary care. This will allow us to compile a sufficient
sample size to look at actual patterns of health services provision in this population. This
would be infeasible with primary data collection strategies, given the low incidence of
psychosis. Additionally, we are proposing to use a novel application of machine-learning
strategies for data analysis, which will allow us to find complex patterns and trajectories
of service use within the rich clinical data of the EMRs. The proposed study will fill a
crucial gap in knowledge on how young people with first-episode psychosis interact with the
primary care system when seeking help for the early symptoms of psychosis, as well as the
practise patterns of family physicians when treating suspected and confirmed cases.
Importantly, this project will incorporate the perspectives of young people with
first-episode psychosis, family physicians and clinicians at EPI programmes to obtain an
in-depth understanding of the role of primary care in EPI.The primary care system is the most widely used service for mental health problems in
Canada, and young people with
first-episode psychosis would benefit from strengthened collaborations between primary care
and EPI services. This is particularly relevant for people in rural and remote areas, where
a lack of psychiatrists necessitates a greater involvement of family physicians in mental
healthcare. Increased help-seeking
in primary care in the period leading up to the first diagnosis of psychosis presents an opportunity for earlier
detection and initiation of treatment, provided that primary care physicians have the
practical knowledge for case recognition and the health service context allows for rapid
access to specialised treatment, when needed. Clinicians encountering these patients in
primary care need to feel confident in their capacity to screen, identify and refer
suspected cases of first-episode psychosis. The outputs from the proposed project will allow for the development
of interventions aimed at better supporting family physicians in their central role in
pathways to care for first-episode psychosis. This research will provide essential
information on how we can most efficiently use existing resources to build linkages between
primary care and EPI services to improve collaboration and continuity of care for young
people with first-episode psychosis.
Authors: Nicky Reynolds; Philippe Wuyts; Steven Badger; Paolo Fusar-Poli; Philip McGuire; Lucia Valmaggia Journal: Early Interv Psychiatry Date: 2014-03-06 Impact factor: 2.732
Authors: Ronald C Kessler; Patricia Berglund; Olga Demler; Robert Jin; Kathleen R Merikangas; Ellen E Walters Journal: Arch Gen Psychiatry Date: 2005-06