| Literature DB >> 30440657 |
Steve J A Majerus, Thomas Knauss, Soumyajit Mandal, Geoff Vince, Margot S Damaser.
Abstract
Subjective analysis of bruits has long been an element of vascular access physical exams. Digital recordings of blood flow bruits-phonoangiograms (PAGs)-may provide an objective, non-imaging measure of vascular access stenosis. We have analyzed the long-term stability in PAGs from typical dialysis patients with arteriovenous fistulas and grafts and found that typical patients have correlated PAG spectra. PAGs can be analyzed using nonlinear, sub-band frequency-domain linear prediction to produce both bruit-enhanced recordings and a bruit-enhanced power envelope. This approach is novel over prior methods because it adaptively predicts signal envelopes based on physiologic properties of blood flow determined from chronic dialysis recipients. Our results indicate that a generalized bruit-enhancing filter can be developed for dialysis vascular access. Outputs from this filter may be analyzed to determine vascular physiology, including re-stenosis risk.Entities:
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Year: 2018 PMID: 30440657 PMCID: PMC6699173 DOI: 10.1109/EMBC.2018.8512588
Source DB: PubMed Journal: Annu Int Conf IEEE Eng Med Biol Soc ISSN: 2375-7477