| Literature DB >> 30429142 |
Michelle Odlum1, Nicole Davis2, Otis Owens3, Michael Preston4, Russell Brewer5, Danielle Black1,6.
Abstract
OBJECTIVE: To understand the gender-specific factors that uniquely contribute to successful ageing in a US population of men and women, 57-85 years of age. This was achieved through the examination of the correlates of subjective well-being defined by health-related quality of life (HRQoL), across several biological and psychosocial determinants of health.Entities:
Keywords: aging; gender differences; health-related quality of life; well-being
Year: 2018 PMID: 30429142 PMCID: PMC6252705 DOI: 10.1136/bmjopen-2017-020962
Source DB: PubMed Journal: BMJ Open ISSN: 2044-6055 Impact factor: 2.692
Figure 1Operationalised Wilson and Cleary model with study-specific biopsychosocial measures. BMI, body mass index.
Characteristics of the developmental and validation models Wilson and Cleary model construct-specific variables
| Construct-specific variables | Developmental cohort (n=1689) | Validation cohort (n=1688) | |||||
| Descriptives | β | 95% CI | Descriptives | β | 95% CI | ||
| Symptom status | Depression (CESD total) | 1.9 ±0.34 | −0.111* | −0.537 to −0.061 | 1.9 ±0.35 | −0.099** | −0.447 to −0.094 |
| Anxiety (HADS total) | 1.8 ±0.45 | −0.201** | −0.499 to −0.291 | 1.8 ±0.45 | −0.212** | −0.563 to −0.270 | |
| Urinary incontinence | 0.42 | −0.070* | −0.112 to 0.076 | 0.43 | −0.059* | −0.238 to 0.028 | |
| Functional status | No physical function difficulty | 0.72 | −0.102** | −0.288 to −0.118 | 0.72 | −0.107** | −0.181 to −0.045 |
| Companionship | 0.39 | −0.168** | −0.238 to −0.075 | 0.40 | −0.166** | −0.207 to −0.129 | |
| Feel isolated | 0.27 | −0.146** | −0.240 to −0.060 | 0.26 | −0.148** | −0.229 to −0.113 | |
| General health perceptions | Self-rated physical health | 3.22±1.05 | 0.121* | 0.021 to 0.175 | 3.19±1.07 | 0.123** | 0.061 to 0. 110 |
| Self-rated mental health | 3.62 ±0.96 | 0.244** | 0.126 to 0.283 | 3.62 ±0.99 | 0.240** | 0.153 to 0.272 | |
| Individual characteristics | Education (>high school) | 0.58 | 0.074* | −0.003 to 0.281 | 0.58 | 0.068* | −0.025 to 0.180 |
| Seen the doctor in last year | 3.06±1.5 | −0.099** | −0.093 to −0.027 | 2.97±1.5 | −0.105** | −0.081 to −0.042 | |
| Environmental characteristics | Has close family/relatives | 0.98 | 0.122** | 0.059 to 0.150 | 0.98 | 0.123** | 0.061 to 0.110 |
| Has friends | 0.97 | 0.079* | −0.001 to 0.105 | 0.97 | 0.066* | −0.010 to 0.136 | |
| Rely on spouse/partner | 0.96 | 0.130** | 0.094 to 0.357 | 0.97 | 0.134* | 0.138 to 0.330 | |
*P<0.05, **P<0.01.
CESD, Center for Epidemiological Studies Depression; HADS, Hospital Anxiety and Depression Scale.
Independent samples t-tests and X2 for Wilson and Cleary model construct-specific variables with men and women (n=3377)
| Men | Women | X2/t-test | df | |
| Biological/physiological function | ||||
| BMI (normal) | 36.5% | 63.5% | 29.0** | 2 |
| Diastolic average | 79.0±12.0 | 81.0±11.5 | −6.4** | 3255 |
| Systolic average | 138.0±0.20.7 | 137.0±21.0 | 1.6 | 3255 |
| Pulse average | 67.7±12.1 | 69.8±11.2 | −5.1** | 3035 |
| Symptom status | ||||
| Pain | 43.8% | 56.2% | 8.9** | 1 |
| Pain: level (no pain) | 50.0% | 50.0% | 11.2 | 6 |
| Depression (CESD total)† | 1.8±0.3 | 2.0±0.4 | −6.6** | 3312 |
| Anxiety (HADS total)† | 1.8±0.5 | 1.8±0.4 | −0.8 | 2627 |
| Fatigue | 54.7% | 45.3% | 3.1 | 3 |
| Urinary incontinence† | 30.2% | 69.8% | 94.7** | 1 |
| Stool incontinence | 30.4% | 69.6% | 15.5** | 1 |
| Functional status | ||||
| No physical function difficulty† | 46.1% | 53.9% | 27.1 | 16 |
| Perceptions of control | 2.3±0.5 | 2.2±0.6 | 2.7** | 2665 |
| Companionship | 49.8% | 50.2% | 21.0** | 3 |
| Feel left out | 54.0% | 46.0% | 3.1 | 3 |
| Feel isolated | 55.8% | 44.2% | 1.5 | 3 |
| General health perceptions | ||||
| Self-rated physical health† | 3.2±1.1 | 3.2±1.0 | −0.7 | 3370 |
| Self-rated mental health† | 3.7±1.0 | 3.6±1.0 | 3.2** | 3372 |
| Individual characteristics | ||||
| Insurance | 96.4% | 95.2% | 10.95** | 1 |
| Age category (≥70) | 62% | 55.8% | 14.1** | 1 |
| Education (> high school) | 57.5% | 55.2% | 1.78 | 1 |
| Race/ethnicity (non-black non-Hispanic) | 74.6% | 73.2% | 3.39 | 1 |
| Seen the doctor in last year† | 3.0±1.5 | 3.04±1.5 | −1.28 | 3367 |
| Environmental characteristics | ||||
| Rely on family | 36.9% | 63.1% | 42.14** | 3 |
| Has close family/relatives† | 38.6% | 61.4% | 52.05** | 5 |
| Rely on friends | 44.3% | 55.7% | 71.78** | 3 |
| Has friends† | 44.9% | 55.1% | 13.12* | 5 |
| Rely on spouse/partner† | 63.3% | 36.70% | 26.92** | 3 |
*P<0.05, **P<0.01.
†Variables that comprise the validated regression model and retained for subsequent gender-related regression analysis.
BMI, body mass index; CESD, Center for Epidemiological Studies Depression; HADS, Hospital Anxiety and Depression Scale.
Wilson and Cleary Model constructs and health-related quality of life outcomes
| Partial R2 | Partial R2 rank | Effect size | Average R2 ranks | Average effect sizes (t values) | |
| Men | |||||
| General health perceptions | 0.24, 1.8 | 1, 3 | 8.3, 5.9 | 2 | 7.1 |
| Functional status | 0.21, 0.07 | 2, 6 | 7.2, 2.2 | 4 | 4.7 |
| Symptom status | 0.14 | 4 | 4.8 | 4 | 4.8 |
| Environmental characteristics | 0.09 | 5 | 3.0 | 5 | 3.0 |
| Women | |||||
| General health perceptions | 0.39 | 1 | 9.4 | 1 | 9.4 |
| Functional status | 0.33 | 2 | 7.9 | 2 | 7.9 |
| Symptom status | 0.03 | 5 | 0.68 | 5 | 0.68 |
| Environmental characteristics | 0.16, 0.12 | 3, 4 | 3.6, 2.6 | 3.5 | 3.09 |
Hierarchy of health-related quality of life contributors based on average effect sizes
| Rank | Item descriptions | |
| Men | ||
| 1st | General health perceptions | Self-rated: mental health and physical health |
| 2nd | Symptom status | Depression |
| 3rd | Functional status | Lack companionship, physical function difficulty |
| 4th | Environmental characteristics | No of close friends |
| Women | ||
| 1st | General health perceptions | Self-rated: mental health |
| 2nd | Functional status | Lack companionship |
| 3rd | Environmental characteristics | Rely on spouse/partner and no of close family |
| 4th | Symptom status | Urinary incontinence |
Demographic characteristics of participants (n=3377)
| N | (%) | |
| Gender | ||
| Men | 1538 | 45.5 |
| 69 or under | 585 | 38.0 |
| 70–79 | 610 | 39.7 |
| 80 or older | 343 | 22.3 |
| Women | 1839 | 54.5 |
| 69 or under | 812 | 44.2 |
| 70–79 | 633 | 34.4 |
| 80 or older | 394 | 21.4 |
| Race | ||
| Men | ||
| Non-black, non-Hispanic | 1147 | 74.6 |
| Black or African-American | 217 | 14.1 |
| Non-black Hispanics | 174 | 11.3 |
| Women | ||
| Non-black, non-Hispanic | 1346 | 73.2 |
| Black or African-American | 300 | 16.3 |
| Non-black Hispanics | 193 | 10.5 |
| Education | ||
| Men | ||
| More than high school | 884 | 57.5 |
| High school or less | 654 | 42.5 |
| Women | ||
| More than high school | 1015 | 55.2 |
| High School or less | 824 | 44.8 |
| Insurance coverage | ||
| Men | ||
| Medicaid–Medicare | 1080 | 83.9 |
| Private | 161 | 12.5 |
| None | 46 | 3.6 |
| Women | ||
| Medicaid–Medicare | 1227 | 79.1 |
| Private | 250 | 16.1 |
| None | 75 | 4.8 |
| Marital status | ||
| Men | ||
| Married | 1201 | 78.1 |
| Not currently married | 337 | 21.9 |
| Women | ||
| Married | 1085 | 59.0 |
| Not currently married | 754 | 41.0 |
| Partnership if non-married | ||
| Men | ||
| No | 231 | 77.5 |
| Women | ||
| No | 659 | 93.1 |