Literature DB >> 30416549

Antiplatelet Therapy in Acute Coronary Syndrome.

Kerry Layne1, Albert Ferro1.   

Abstract

Antiplatelet agents have for decades been used to improve outcomes in patients with acute coronary syndromes and have become increasingly valued, not only for their antithrombotic properties but also for their anti-inflammatory effects. The drug class continues to evolve as novel agents with increasingly efficacious antiplatelet actions are identified. This review will discuss antiplatelet agents, including aspirin, the P2Y12 receptor antagonists and the glycoprotein IIb/IIIa inhibitors, that are currently used to treat patients with unstable angina and myocardial infarction, focusing on their pharmacological properties and the clinical evidence supporting their use.

Entities:  

Keywords:  Antiplatelet agent; IIb/IIIa inhibitors; P2Y12 receptor antagonist; acute coronary syndromes; anti-inflammatory; antithrombotic; aspirin; glycoprotein

Year:  2017        PMID: 30416549      PMCID: PMC6206448          DOI: 10.15420/ecr.2016:34:2

Source DB:  PubMed          Journal:  Eur Cardiol        ISSN: 1758-3756


  68 in total

Review 1.  Prasugrel.

Authors:  Stephen D Wiviott; Elliott M Antman; Eugene Braunwald
Journal:  Circulation       Date:  2010-07-27       Impact factor: 29.690

2.  Glycoprotein IIb-IIIa inhibitors - do we still need them?

Authors:  Vijayakumar Subban; K Sarat Chandra
Journal:  Indian Heart J       Date:  2013-04-25

Review 3.  Switching of platelet P2Y12 receptor inhibitors in patients with acute coronary syndromes undergoing percutaneous coronary intervention: Review of the literature and practical considerations.

Authors:  Leonardo De Luca; Piera Capranzano; Giuseppe Patti; Guido Parodi
Journal:  Am Heart J       Date:  2016-03-17       Impact factor: 4.749

4.  Impaired platelet-connective-tissue reaction in man after aspirin ingestion.

Authors:  H J Weiss; L M Aledort
Journal:  Lancet       Date:  1967-09-02       Impact factor: 79.321

5.  McKittrick-Wheelock syndrome: a rare cause of diarrhoea.

Authors:  Dragan Lepur; Igor Klinar; Branko Mise; Josip Himbele; Zoran Vranjican; Bruno Barsić
Journal:  Eur J Gastroenterol Hepatol       Date:  2006-05       Impact factor: 2.566

6.  A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee.

Authors: 
Journal:  Lancet       Date:  1996-11-16       Impact factor: 79.321

7.  Safety, tolerability, and initial efficacy of AZD6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-ST-segment elevation acute coronary syndrome: primary results of the DISPERSE-2 trial.

Authors:  Christopher P Cannon; Steen Husted; Robert A Harrington; Benjamin M Scirica; Håkan Emanuelsson; Gary Peters; Robert F Storey
Journal:  J Am Coll Cardiol       Date:  2007-10-23       Impact factor: 24.094

8.  Intravenous platelet blockade with cangrelor during PCI.

Authors:  Deepak L Bhatt; A Michael Lincoff; C Michael Gibson; Gregg W Stone; Steven McNulty; Gilles Montalescot; Neal S Kleiman; Shaun G Goodman; Harvey D White; Kenneth W Mahaffey; Charles V Pollack; Steven V Manoukian; Petr Widimsky; Derek P Chew; Fernando Cura; Ivan Manukov; Frantisek Tousek; M Zubair Jafar; Jaspal Arneja; Simona Skerjanec; Robert A Harrington
Journal:  N Engl J Med       Date:  2009-12-10       Impact factor: 91.245

9.  A prospective, blinded determination of the natural history of aspirin resistance among stable patients with cardiovascular disease.

Authors:  Patricia A Gum; Kandice Kottke-Marchant; Patricia A Welsh; Jennifer White; Eric J Topol
Journal:  J Am Coll Cardiol       Date:  2003-03-19       Impact factor: 24.094

Review 10.  Anti-platelet therapy: ADP receptor antagonists.

Authors:  Yanushi Dullewe Wijeyeratne; Stan Heptinstall
Journal:  Br J Clin Pharmacol       Date:  2011-10       Impact factor: 4.335

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  3 in total

1.  New perspectives on treatment strategies for patient with acute myeloid leukemia and complex karyotype abnormalities after percutaneous coronary intervention: A case report.

Authors:  Jie Wang; Rong Chen; Xiaoqi Lin; Yubo Wang; Jian-Hua Wang; Yun Wu
Journal:  Medicine (Baltimore)       Date:  2019-07       Impact factor: 1.817

2.  Adherence to prophylactic dual antiplatelet therapy in patients with acute coronary syndrome - A study conducted at a Saudi university hospital.

Authors:  Ziyad Alrabiah; Syed Wajid; Ibrahim Alsulaihim; Sultan Alghadeer; Abdulaziz Alhossan; Salmeen D Babelghaith; Mohamed Al-Arifi
Journal:  Saudi Pharm J       Date:  2020-02-03       Impact factor: 4.330

Review 3.  Factors Affecting the Formation and Treatment of Thrombosis by Natural and Synthetic Compounds.

Authors:  Anna Lichota; Eligia M Szewczyk; Krzysztof Gwozdzinski
Journal:  Int J Mol Sci       Date:  2020-10-27       Impact factor: 5.923

  3 in total

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