Literature DB >> 30409057

Automatic prediction of intelligible speaking rate for individuals with ALS from speech acoustic and articulatory samples.

Jun Wang1,2, Prasanna V Kothalkar1, Myungjong Kim1, Andrea Bandini3, Beiming Cao1, Yana Yunusova3, Thomas F Campbell2, Daragh Heitzman4, Jordan R Green5.   

Abstract

Purpose: This research aimed to automatically predict intelligible speaking rate for individuals with Amyotrophic Lateral Sclerosis (ALS) based on speech acoustic and articulatory samples. Method: Twelve participants with ALS and two normal subjects produced a total of 1831 phrases. NDI Wave system was used to collect tongue and lip movement and acoustic data synchronously. A machine learning algorithm (i.e. support vector machine) was used to predict intelligible speaking rate (speech intelligibility × speaking rate) from acoustic and articulatory features of the recorded samples. Result: Acoustic, lip movement, and tongue movement information separately, yielded a R2 of 0.652, 0.660, and 0.678 and a Root Mean Squared Error (RMSE) of 41.096, 41.166, and 39.855 words per minute (WPM) between the predicted and actual values, respectively. Combining acoustic, lip and tongue information we obtained the highest R2 (0.712) and the lowest RMSE (37.562 WPM).
Conclusion: The results revealed that our proposed analyses predicted the intelligible speaking rate of the participant with reasonably high accuracy by extracting the acoustic and/or articulatory features from one short speech sample. With further development, the analyses may be well-suited for clinical applications that require automatic speech severity prediction.

Entities:  

Keywords:  amyotrophic lateral sclerosis; dysarthria; intelligible speaking rate; machine learning; speech kinematics; support vector machine

Mesh:

Year:  2018        PMID: 30409057      PMCID: PMC6506394          DOI: 10.1080/17549507.2018.1508499

Source DB:  PubMed          Journal:  Int J Speech Lang Pathol        ISSN: 1754-9507            Impact factor:   2.484


  26 in total

1.  An Optimal Set of Flesh Points on Tongue and Lips for Speech-Movement Classification.

Authors:  Jun Wang; Ashok Samal; Panying Rong; Jordan R Green
Journal:  J Speech Lang Hear Res       Date:  2016-02       Impact factor: 2.297

Review 2.  The epidemiology of ALS and the role of population-based registries.

Authors:  Ettore Beghi; Giancarlo Logroscino; Adriano Chiò; Orla Hardiman; Douglas Mitchell; Robert Swingler; Bryan J Traynor
Journal:  Biochim Biophys Acta       Date:  2006-09-29

3.  Regularized Speaker Adaptation of KL-HMM for Dysarthric Speech Recognition.

Authors:  Myungjong Kim; Younggwan Kim; Joohong Yoo; Jun Wang; Hoirin Kim
Journal:  IEEE Trans Neural Syst Rehabil Eng       Date:  2017-03-13       Impact factor: 3.802

Review 4.  Amyotrophic lateral sclerosis.

Authors:  Matthew C Kiernan; Steve Vucic; Benjamin C Cheah; Martin R Turner; Andrew Eisen; Orla Hardiman; James R Burrell; Margaret C Zoing
Journal:  Lancet       Date:  2011-02-04       Impact factor: 79.321

Review 5.  Amyotrophic lateral sclerosis: a review of current concepts.

Authors:  Michael Strong; Jeffrey Rosenfeld
Journal:  Amyotroph Lateral Scler Other Motor Neuron Disord       Date:  2003-09

6.  Physiologic deficits in the orofacial system underlying dysarthria in amyotrophic lateral sclerosis.

Authors:  S E Langmore; M E Lehman
Journal:  J Speech Hear Res       Date:  1994-02

7.  Communication Support for People with ALS.

Authors:  David Beukelman; Susan Fager; Amy Nordness
Journal:  Neurol Res Int       Date:  2011-04-14

8.  On the Acoustics of Emotion in Audio: What Speech, Music, and Sound have in Common.

Authors:  Felix Weninger; Florian Eyben; Björn W Schuller; Marcello Mortillaro; Klaus R Scherer
Journal:  Front Psychol       Date:  2013-05-27

9.  Bulbar and speech motor assessment in ALS: challenges and future directions.

Authors:  Jordan R Green; Yana Yunusova; Mili S Kuruvilla; Jun Wang; Gary L Pattee; Lori Synhorst; Lorne Zinman; James D Berry
Journal:  Amyotroph Lateral Scler Frontotemporal Degener       Date:  2013-07-30       Impact factor: 4.092

10.  Predicting Speech Intelligibility Decline in Amyotrophic Lateral Sclerosis Based on the Deterioration of Individual Speech Subsystems.

Authors:  Panying Rong; Yana Yunusova; Jun Wang; Lorne Zinman; Gary L Pattee; James D Berry; Bridget Perry; Jordan R Green
Journal:  PLoS One       Date:  2016-05-05       Impact factor: 3.240

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  6 in total

1.  Reliability and validity of speech & pause measures during passage reading in ALS.

Authors:  Carolina Barnett; Jordan R Green; Reeman Marzouqah; Kaila L Stipancic; James D Berry; Lawrence Korngut; Angela Genge; Christen Shoesmith; Hannah Briemberg; Agessandro Abrahao; Sanjay Kalra; Lorne Zinman; Yana Yunusova
Journal:  Amyotroph Lateral Scler Frontotemporal Degener       Date:  2019-12-06       Impact factor: 4.092

2.  "You Say Severe, I Say Mild": Toward an Empirical Classification of Dysarthria Severity.

Authors:  Kaila L Stipancic; Kira M Palmer; Hannah P Rowe; Yana Yunusova; James D Berry; Jordan R Green
Journal:  J Speech Lang Hear Res       Date:  2021-11-11       Impact factor: 2.674

3.  The Effects of Symptom Onset Location on Automatic Amyotrophic Lateral Sclerosis Detection Using the Correlation Structure of Articulatory Movements.

Authors:  Alan Wisler; Kristin Teplansky; Daragh Heitzman; Jun Wang
Journal:  J Speech Lang Hear Res       Date:  2021-03-01       Impact factor: 2.297

4.  Detection of Bulbar Involvement in Patients With Amyotrophic Lateral Sclerosis by Machine Learning Voice Analysis: Diagnostic Decision Support Development Study.

Authors:  Francesc Solsona; Alberto Tena; Francec Claria; Einar Meister; Monica Povedano
Journal:  JMIR Med Inform       Date:  2021-03-10

Review 5.  Addressing heterogeneity in amyotrophic lateral sclerosis CLINICAL TRIALS.

Authors:  Namita A Goyal; James D Berry; Anthony Windebank; Nathan P Staff; Nicholas J Maragakis; Leonard H van den Berg; Angela Genge; Robert Miller; Robert H Baloh; Ralph Kern; Yael Gothelf; Chaim Lebovits; Merit Cudkowicz
Journal:  Muscle Nerve       Date:  2020-01-22       Impact factor: 3.217

Review 6.  Biomedical signals and machine learning in amyotrophic lateral sclerosis: a systematic review.

Authors:  Felipe Fernandes; Ingridy Barbalho; Daniele Barros; Ricardo Valentim; César Teixeira; Jorge Henriques; Paulo Gil; Mário Dourado Júnior
Journal:  Biomed Eng Online       Date:  2021-06-15       Impact factor: 2.819

  6 in total

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