Literature DB >> 3040709

Phytic acid. A natural antioxidant.

E Graf, K L Empson, J W Eaton.   

Abstract

The catalysis by iron of radical formation and subsequent oxidative damage has been well documented. Although many iron-chelating agents potentiate reactive oxygen formation and lipid peroxidation, phytic acid (abundant in edible legumes, cereals, and seeds) forms an iron chelate which greatly accelerates Fe2+-mediated oxygen reduction yet blocks iron-driven hydroxyl radical generation and suppresses lipid peroxidation. Furthermore, high concentrations of phytic acid prevent browning and putrefaction of various fruits and vegetables by inhibiting polyphenol oxidase. These observations indicate an important antioxidant function for phytate in seeds during dormancy and suggest that phytate may be a substitute for presently employed preservatives, many of which pose potential health hazards.

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Year:  1987        PMID: 3040709

Source DB:  PubMed          Journal:  J Biol Chem        ISSN: 0021-9258            Impact factor:   5.157


  43 in total

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Authors:  Beatriz González; Jose Ignacio Baños-Sanz; Maider Villate; Charles Alistair Brearley; Julia Sanz-Aparicio
Journal:  Proc Natl Acad Sci U S A       Date:  2010-05-07       Impact factor: 11.205

2.  Alkaline phytase activity in nonionic detergent extracts of legume seeds.

Authors:  J J Scott
Journal:  Plant Physiol       Date:  1991-04       Impact factor: 8.340

3.  Inositols prevent and reverse endothelial dysfunction in diabetic rat and rabbit vasculature metabolically and by scavenging superoxide.

Authors:  N R F Nascimento; L M A Lessa; M R Kerntopf; C M Sousa; R S Alves; M G R Queiroz; J Price; D B Heimark; J Larner; X Du; M Brownlee; A Gow; C Davis; M C Fonteles
Journal:  Proc Natl Acad Sci U S A       Date:  2005-12-22       Impact factor: 11.205

4.  Photoreduction and incorporation of iron into ferritins.

Authors:  J P Laulhère; A M Labouré; J F Briat
Journal:  Biochem J       Date:  1990-07-01       Impact factor: 3.857

5.  A simple and rapid colorimetric method for determination of phytate in urine.

Authors:  Antonia Costa-Bauza; F Grases; I Gomila; A Rodriguez; R M Prieto; F Tur
Journal:  Urol Res       Date:  2012-04-05

6.  Comparison of autoclave, microwave, IR and UV-C stabilization of whole wheat flour branny fractions upon the nutritional properties of whole wheat bread.

Authors:  Mustafa Kürşat Demir; Adem Elgün
Journal:  J Food Sci Technol       Date:  2011-08-02       Impact factor: 2.701

7.  Prooxidant and antioxidant effects of Trolox on ferric ion-induced oxidation of erythrocyte membrane lipids.

Authors:  K M Ko; P K Yick; M K Poon; S P Ip
Journal:  Mol Cell Biochem       Date:  1994-12-07       Impact factor: 3.396

8.  Ferric ion-induced lipid peroxidation in erythrocyte membranes: effects of phytic acid and butylated hydroxytoluene.

Authors:  K M Ko; D V Godin
Journal:  Mol Cell Biochem       Date:  1990-06-25       Impact factor: 3.396

9.  Do mammals make all their own inositol hexakisphosphate?

Authors:  Andrew J Letcher; Michael J Schell; Robin F Irvine
Journal:  Biochem J       Date:  2008-12-01       Impact factor: 3.857

10.  Advances in maize genomics and their value for enhancing genetic gains from breeding.

Authors:  Yunbi Xu; Debra J Skinner; Huixia Wu; Natalia Palacios-Rojas; Jose Luis Araus; Jianbing Yan; Shibin Gao; Marilyn L Warburton; Jonathan H Crouch
Journal:  Int J Plant Genomics       Date:  2009-08-12
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