Literature DB >> 30406849

A rapid introduction to neurological biochemistry using Drosophila melanogaster.

Setareh S Chong1, Anthony J Wilkinson2, Sangeeta Chawla3.   

Abstract

Short, cost-effective teaching activities are a useful way of providing an integrated view on biological processes. Here we describe a brief, hands-on workshop that allows pre-university students to explore their understanding of a neurological pathway from its chemical bases to phenotype. The workshop effectively introduces the students to data collection and analysis in an enjoyable way and at an appropriate level, determined by an end of session feedback survey. The design of the workshop can be adapted and scaled to generate diverse sessions such as university teaching practicals or summer school training workshops.

Entities:  

Keywords:  Dopamine; LRRK2; Outreach; Parkinson’s disease; Teaching

Mesh:

Year:  2018        PMID: 30406849     DOI: 10.1007/s10158-018-0220-8

Source DB:  PubMed          Journal:  Invert Neurosci        ISSN: 1354-2516


  19 in total

1.  Rapid iterative negative geotaxis (RING): a new method for assessing age-related locomotor decline in Drosophila.

Authors:  Julia Warner Gargano; Ian Martin; Poonam Bhandari; Michael S Grotewiel
Journal:  Exp Gerontol       Date:  2005-03-19       Impact factor: 4.032

2.  Loss of LRRK2/PARK8 induces degeneration of dopaminergic neurons in Drosophila.

Authors:  Sung Bae Lee; Wonho Kim; Sungkyu Lee; Jongkyeong Chung
Journal:  Biochem Biophys Res Commun       Date:  2007-05-04       Impact factor: 3.575

3.  Knockdown transgenic Lrrk Drosophila resists paraquat-induced locomotor impairment and neurodegeneration: A therapeutic strategy for Parkinson's disease.

Authors:  Diana Quintero-Espinosa; Marlene Jimenez-Del-Rio; Carlos Velez-Pardo
Journal:  Brain Res       Date:  2016-12-30       Impact factor: 3.252

Review 4.  What genetics tells us about the causes and mechanisms of Parkinson's disease.

Authors:  Olga Corti; Suzanne Lesage; Alexis Brice
Journal:  Physiol Rev       Date:  2011-10       Impact factor: 37.312

Review 5.  Parkinson's disease.

Authors:  Lorraine V Kalia; Anthony E Lang
Journal:  Lancet       Date:  2015-04-19       Impact factor: 79.321

Review 6.  100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future.

Authors:  Hugo J Bellen; Chao Tong; Hiroshi Tsuda
Journal:  Nat Rev Neurosci       Date:  2010-07       Impact factor: 34.870

7.  Presenting your structures: the CCP4mg molecular-graphics software.

Authors:  S McNicholas; E Potterton; K S Wilson; M E M Noble
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2011-03-18

Review 8.  Taking Stock of the Drosophila Research Ecosystem.

Authors:  David Bilder; Kenneth D Irvine
Journal:  Genetics       Date:  2017-07       Impact factor: 4.562

Review 9.  Maintaining the brain: insight into human neurodegeneration from Drosophila melanogaster mutants.

Authors:  Derek Lessing; Nancy M Bonini
Journal:  Nat Rev Genet       Date:  2009-06       Impact factor: 53.242

10.  Making long-term memories in minutes: a spaced learning pattern from memory research in education.

Authors:  Paul Kelley; Terry Whatson
Journal:  Front Hum Neurosci       Date:  2013-09-25       Impact factor: 3.169

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