Literature DB >> 20383202

100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future.

Hugo J Bellen1, Chao Tong, Hiroshi Tsuda.   

Abstract

Discoveries in fruit flies have greatly contributed to our understanding of neuroscience. The use of an unparalleled wealth of tools, many of which originated between 1910–1960, has enabled milestone discoveries in nervous system development and function. Such findings have triggered and guided many research efforts in vertebrate neuroscience. After 100 years, fruit flies continue to be the choice model system for many neuroscientists. The combinational use of powerful research tools will ensure that this model organism will continue to lead to key discoveries that will impact vertebrate neuroscience.

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Year:  2010        PMID: 20383202      PMCID: PMC4022039          DOI: 10.1038/nrn2839

Source DB:  PubMed          Journal:  Nat Rev Neurosci        ISSN: 1471-003X            Impact factor:   34.870


  215 in total

1.  Molecular characterization of Shaker, a Drosophila gene that encodes a potassium channel.

Authors:  A Kamb; L E Iverson; M A Tanouye
Journal:  Cell       Date:  1987-07-31       Impact factor: 41.582

2.  Mutation in the alpha-synuclein gene identified in families with Parkinson's disease.

Authors:  M H Polymeropoulos; C Lavedan; E Leroy; S E Ide; A Dehejia; A Dutra; B Pike; H Root; J Rubenstein; R Boyer; E S Stenroos; S Chandrasekharappa; A Athanassiadou; T Papapetropoulos; W G Johnson; A M Lazzarini; R C Duvoisin; G Di Iorio; L I Golbe; R L Nussbaum
Journal:  Science       Date:  1997-06-27       Impact factor: 47.728

3.  P[acman]: a BAC transgenic platform for targeted insertion of large DNA fragments in D. melanogaster.

Authors:  Koen J T Venken; Yuchun He; Roger A Hoskins; Hugo J Bellen
Journal:  Science       Date:  2006-11-30       Impact factor: 47.728

4.  Synaptic vesicle size and number are regulated by a clathrin adaptor protein required for endocytosis.

Authors:  B Zhang; Y H Koh; R B Beckstead; V Budnik; B Ganetzky; H J Bellen
Journal:  Neuron       Date:  1998-12       Impact factor: 17.173

Review 5.  WNTs tune up the neuromuscular junction.

Authors:  Ceren Korkut; Vivian Budnik
Journal:  Nat Rev Neurosci       Date:  2009-09       Impact factor: 34.870

6.  Electrophysiological correlates of rest and activity in Drosophila melanogaster.

Authors:  Douglas A Nitz; Bruno van Swinderen; Giulio Tononi; Ralph J Greenspan
Journal:  Curr Biol       Date:  2002-11-19       Impact factor: 10.834

7.  Targeted mutagenesis by homologous recombination in D. melanogaster.

Authors:  Yikang S Rong; Simon W Titen; Heng B Xie; Mary M Golic; Michael Bastiani; Pradip Bandyopadhyay; Baldomero M Olivera; Michael Brodsky; Gerald M Rubin; Kent G Golic
Journal:  Genes Dev       Date:  2002-06-15       Impact factor: 11.361

Review 8.  The genetics of mammalian circadian order and disorder: implications for physiology and disease.

Authors:  Joseph S Takahashi; Hee-Kyung Hong; Caroline H Ko; Erin L McDearmon
Journal:  Nat Rev Genet       Date:  2008-10       Impact factor: 53.242

9.  The neurogenic gene Delta of Drosophila melanogaster is expressed in neurogenic territories and encodes a putative transmembrane protein with EGF-like repeats.

Authors:  H Vässin; K A Bremer; E Knust; J A Campos-Ortega
Journal:  EMBO J       Date:  1987-11       Impact factor: 11.598

10.  Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis.

Authors:  Alexandra Van Keymeulen; Guilhem Mascre; Khalil Kass Youseff; Itamar Harel; Cindy Michaux; Natalie De Geest; Caroline Szpalski; Younes Achouri; Wilhelm Bloch; Bassem A Hassan; Cédric Blanpain
Journal:  J Cell Biol       Date:  2009-09-28       Impact factor: 10.539

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  143 in total

Review 1.  Genetic studies in intellectual disability and related disorders.

Authors:  Lisenka E L M Vissers; Christian Gilissen; Joris A Veltman
Journal:  Nat Rev Genet       Date:  2015-10-27       Impact factor: 53.242

Review 2.  New approaches for studying synaptic development, function, and plasticity using Drosophila as a model system.

Authors:  C Andrew Frank; Xinnan Wang; Catherine A Collins; Avital A Rodal; Quan Yuan; Patrik Verstreken; Dion K Dickman
Journal:  J Neurosci       Date:  2013-11-06       Impact factor: 6.167

3.  Effects of light at night on laboratory animals and research outcomes.

Authors:  Kathryn M Emmer; Kathryn L G Russart; William H Walker; Randy J Nelson; A Courtney DeVries
Journal:  Behav Neurosci       Date:  2018-06-28       Impact factor: 1.912

4.  Miles to go (mtgo) encodes FNDC3 proteins that interact with the chaperonin subunit CCT3 and are required for NMJ branching and growth in Drosophila.

Authors:  Adeela Syed; Tamás Lukacsovich; Miles Pomeroy; A Jane Bardwell; Gentry Thomas Decker; Katrina G Waymire; Judith Purcell; Weijian Huang; James Gui; Emily M Padilla; Cindy Park; Antor Paul; Thai Bin T Pham; Yanete Rodriguez; Stephen Wei; Shane Worthge; Ronak Zebarjedi; Bing Zhang; Lee Bardwell; J Lawrence Marsh; Grant R MacGregor
Journal:  Dev Biol       Date:  2018-10-25       Impact factor: 3.582

Review 5.  Extracellular matrix and its receptors in Drosophila neural development.

Authors:  Kendal Broadie; Stefan Baumgartner; Andreas Prokop
Journal:  Dev Neurobiol       Date:  2011-11       Impact factor: 3.964

6.  Differential centrifugation-based biochemical fractionation of the Drosophila adult CNS.

Authors:  Harald Depner; Janine Lützkendorf; Husam A Babkir; Stephan J Sigrist; Matthew G Holt
Journal:  Nat Protoc       Date:  2014-11-13       Impact factor: 13.491

7.  Live imaging of axonal transport in Drosophila pupal brain explants.

Authors:  Caroline Medioni; Anne Ephrussi; Florence Besse
Journal:  Nat Protoc       Date:  2015-03-12       Impact factor: 13.491

8.  A rapid introduction to neurological biochemistry using Drosophila melanogaster.

Authors:  Setareh S Chong; Anthony J Wilkinson; Sangeeta Chawla
Journal:  Invert Neurosci       Date:  2018-11-08

Review 9.  Comparative approaches to the study of physiology: Drosophila as a physiological tool.

Authors:  Wendi S Neckameyer; Kathryn J Argue
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2012-12-05       Impact factor: 3.619

Review 10.  I Believe I Can Fly!: Use of Drosophila as a Model Organism in Neuropsychopharmacology Research.

Authors:  Anjana S Narayanan; Adrian Rothenfluh
Journal:  Neuropsychopharmacology       Date:  2015-10-30       Impact factor: 7.853

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