Literature DB >> 3040634

Production of gallium-66, a short-lived, positron emitting radionuclide.

J Zweit, H Sharma, S Downey.   

Abstract

The excitation functions for the production of 66Ga and some other radionuclides produced by the 4He-particle bombardment of a natural copper target have been measured up to 31 MeV incident energy. The radiochemical separation of 66Ga from the irradiated copper target as well as from the other radionuclides formed is described. The yield of 66Ga at 18 MeV incident energy is 708 microCi/microAh at end of bombardment and the contamination of 67Ga is 0.25%. The intended use of the 66Ga produced is to label monoclonal antibodies for PET scanning.

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Year:  1987        PMID: 3040634     DOI: 10.1016/0883-2889(87)90194-8

Source DB:  PubMed          Journal:  Int J Rad Appl Instrum A        ISSN: 0883-2889


  3 in total

1.  Production of carrier-free 66Ga and labeling of antimyosin antibody for positron imaging of acute myocardial infarction.

Authors:  P Goethals; M Coene; G Slegers; D Vogelaers; J Everaert; I Lemahieu; F Colardyn; G R Heyndrickx
Journal:  Eur J Nucl Med       Date:  1990

Review 2.  Radioimmunoimaging with longer-lived positron-emitting radionuclides: potentials and challenges.

Authors:  Tapan K Nayak; Martin W Brechbiel
Journal:  Bioconjug Chem       Date:  2009-05-20       Impact factor: 4.774

3.  66Ga: A Novelty or a Valuable Preclinical Screening Tool for the Design of Targeted Radiopharmaceuticals?

Authors:  Alejandro Amor-Coarasa; James M Kelly; Shashikanth Ponnala; Anastasia Nikolopoulou; Clarence Williams; John W Babich
Journal:  Molecules       Date:  2018-10-09       Impact factor: 4.411

  3 in total

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